{"instituterec":{"StatusID":1,"InsID":14610,"StandardName":"Laboratory of Immunology and Animal Biotechnology","OrigName":null,"OrigNameLangCode":null,"OrigNameLangID":null,"Acronym":"UGent","HigherInsID":14145,"VlizCoreFlag":1,"AdrID":163597,"Line1":"Coupure Links 653 blok B","Line2":"9000 Gent","Line3":null,"Line4":null,"Phone":null,"GSM":null,"Email":null,"Lat":null,"Lon":null,"OrigNameLang":null,"OrigNameLangNL":null,"AbstractEnglish":"The laboratory for Immunology and Animal Biotechnology conducts research which is clustered among three disciplines: \r\n\r\n\r\nAquaculture is currently the fastest growing food producing sector in the world, due to the increasing demand for seafood. The larval phase of the aquaculture production cycle is however still affected by low and unpredictable survival, high susceptibility to diseases (caused e.g. by Vibrio spp.) and slow growth, all constituting bottlenecks for the sustainable expansion of aquaculture. The laboratory is studying the innate immune system of fish larvae and larvae of shrimp and mussels in order to design immunostimulants and recombinant-, DNA and mRNA vaccines for inducing innate immune memory and decreasing larval dead.","AbstractOtherLang":"Het laboratorium voor Immunologie en Dierlijke Biotechnologie verricht onderzoek dat geclusterd is rond drie disciplines: \r\n\r\n\r\nAquacultuur is momenteel de snelst groeiende voedselproducerende sector ter wereld, als gevolg van de toenemende vraag naar zeevoedsel. De larvale fase van de aquacultuurproductiecyclus wordt echter nog steeds gekenmerkt door een lage en onvoorspelbare overleving, een hoge gevoeligheid voor ziekten (veroorzaakt door bv. Vibrio spp.) en een trage groei, wat allemaal knelpunten vormen voor de duurzame uitbreiding van de aquacultuur. Het laboratorium bestudeert het aangeboren immuunsysteem van vis-, garnaal- en mossellarven om immunostimulanten en recombinant-, DNA- en mRNA-vaccins te ontwerpen voor het induceren van aangeboren immuungeheugen en het verminderen van larvale sterfte.","AbstractLangCode":null,"AbstractLangID":null,"AbstractLang":null,"AbstractLangNL":null,"SuccessorOfInsID":null,"DateLastModified":{"date":"2024-06-04 01:34:19.073000","timezone_type":1,"timezone":"+00:00"},"PrevIns":null,"PrevAcro":null,"PublicFlag":1,"CheckedFlag":0,"ParID":471,"InstituteType":"Scientific","EnvName":"Belgium","ISO3166":"BE","LevelName":null,"ND":"2020-08-19","UD":"2021-10-29","EncAddress":", Coupure Links 653 blok B, 9000 Gent, Belgium"},"parent":{"PublicFlag":1,"InsID":14145,"OrigNameLangCode":"en","OrigNameLangID":15,"FullStandardName":"Universiteit Gent; Faculteit Bio-ingenieurswetenschappen; Vakgroep Dierwetenschappen en Aquatische Ecologie","FullOrigName":"Ghent University; Faculty of Bioscience Engineering; Department of Animal Sciences and Aquatic Ecology","Acronym":"UGent"},"institutes":null,"references":[{"BRefID":437529,"RR":"Kashem, M.A.; Haniswita, H.; Sumon, T.A.; Vandeputte, M.; Drouillon, M.; Declercq, A.; Bossier, P.; Vanrompay, D. (2026). Probiotic Bacillus species to mitigate acute hepatopancreatic necrosis disease (AHPND) in shrimp aquaculture. Aquaculture 614: 743483. https://dx.doi.org/10.1016/j.aquaculture.2025.743483","PeerRev":1},{"BRefID":382713,"RR":"Roy, S.; Wille, M.; Norouzitallab, P.; Vanrompay, D.; Bossier, P. (2024). Parental training with phloroglucinol protects their offspring from biotic and abiotic stressors in Macrobrachium rosenbergii. Aquaculture 581: 740448. https://dx.doi.org/10.1016/j.aquaculture.2023.740448","PeerRev":1},{"BRefID":391358,"RR":"Vandeputte, M.; Coppens, S.; Bossier, P.; Vereecke, N.; Vanrompay, D. (2024). Genomic mining of Vibrio parahaemolyticus highlights prevalence of antimicrobial resistance genes and new genetic markers associated with AHPND and tdh plus /trh plus genotypes. BMC Genom. 25(1): 178. https://dx.doi.org/10.1186/s12864-024-10093-9","PeerRev":1},{"BRefID":391544,"RR":"Roy, S.; Kumar, V.; Bossier, P.; Norouzitallab, P.; Vanrompay, D. (2022). Phloroglucinol treatment of brine shrimp induces transgenerational epigenetic inherited resistance against Vibrio parahaemolyticus. Fish Shellfish Immunol. 131: 1328-1328","PeerRev":1},{"BRefID":362462,"RR":"Roy, S.; Baruah, K.; Bossier, P.; Vanrompay, D.; Norouzitallab, P. (2022). Induction of transgenerational innate immune memory against Vibrio infections in a brine shrimp (Artemia franciscana) model. Aquaculture 557: 738309. https://dx.doi.org/10.1016/j.aquaculture.2022.738309","PeerRev":1},{"BRefID":353271,"RR":"De Vos, S.; Rombauts, S.; Coussement, L.; Dermauw, W.; Vuylsteke, M.; Sorgeloos, P.; Clegg, J.S.; Nambu, Z.; Van Nieuwerburgh, F.; Norouzitallab, P.; Van Leeuwen, T.; De Meyer, T.; Van Stappen, G.; Van de Peer, Y.; Bossier, P. (2021). The genome of the extremophile Artemia provides insight into strategies to cope with extreme environments. BMC Genom. 22(1): 635. https://dx.doi.org/10.1186/s12864-021-07937-z","PeerRev":1},{"BRefID":337846,"RR":"Roy, S.; Bossier, P.; Norouzitallab, P.; Vanrompay, D. (2020). Trained immunity and perspectives for shrimp aquaculture. Reviews in Aquaculture 12(4): 2351-2370. https://hdl.handle.net/10.1111/raq.12438","PeerRev":1},{"BRefID":322727,"RR":"Yaacob, E.N.; Norouzitallab, P.; De Geest, B.G.; Bajek, A.; Dierckens, K.; Bossier, P.; Vanrompay, D. (2020). Recombinant DnaK orally administered protects axenic European sea bass against vibriosis. Frontiers in Immunology 10: 3162. https://dx.doi.org/10.3389/fimmu.2019.03162","PeerRev":1},{"BRefID":338083,"RR":"Junprung, W.; Norouzitallab, P.; De Vos, S.; Tassanakajon, A.; Nguyen, V.D.; Van Stappen, G.; Bossier, P. (2019). Sequence and expression analysis of HSP70 family genes in Artemia franciscana. NPG Scientific Reports 9: 8391. https://hdl.handle.net/10.1038/s41598-019-44884-y","PeerRev":1},{"BRefID":310410,"RR":"Norouzitallab, P.; Baruah, K.; Vanrompay, D.; Bossier, P. (2019). Teaching shrimps self-defense to fight infections. Trends Biotechnol. 37(1): 16-19. https://dx.doi.org/10.1016/j.tibtech.2018.05.007","PeerRev":1},{"BRefID":322846,"RR":"Roy, S.; Kumar, V.; Bossier, P.; Norouzitallab, P.; Vanrompay, D. (2019). Phloroglucinol treatment induces transgenerational epigenetic inherited resistance against Vibrio infections and thermal stress in a brine shrimp (Artemia franciscana) model. Frontiers in Immunology 10: 2745. https://dx.doi.org/10.3389/fimmu.2019.02745","PeerRev":1},{"BRefID":307886,"RR":"Martin-Rodriguez, A.J.; Alvarez-Mendez, S.J.; Overa, C.; Baruah, K.; Lourenço, T.M.; Norouzitallab, P.; Bossier, P.; Martin, V.S.; Fernández, J.J. (2018). The 9H-fluoren vinyl ether derivative SAM461 inhibits bacterial luciferase activity and protects Artemia franciscana from luminescent vibriosis. Frontiers in Cellular and Infection Microbiology 8: 11. https://dx.doi.org/10.3389/fcimb.2018.00368","PeerRev":1},{"BRefID":307904,"RR":"Yaacob, E.N.; De Geest, B.G.; Goethals, J.; Bajek, A.; Dierckens, K.; Bossier, P.; Vanrompay, D. (2018). Recombinant ferritin-H induces immunosuppression in European sea bass larvae (Dicentrarchus labrax) rather than immunostimulation and protection against a Vibrio anguillarum infection. Vet. Immunol. Immunopathol. 204: 19-27. https://dx.doi.org/10.1016/j.vetimm.2018.09.001","PeerRev":1},{"BRefID":293739,"RR":"Baruah, K.; Norouzitallab, P.; Phong, H.P.P.D.; Smagghe, G.; Bossier, P. (2017). Enhanced resistance against Vibrio harveyi infection by carvacrol and its association with the induction of heat shock protein 72 in gnotobiotic Artemia franciscana. Cell Stress Chap. 22(3): 377-387. https://dx.doi.org/10.1007/s12192-017-0775-z","PeerRev":1},{"BRefID":293673,"RR":"Yaacob, E.N.; Goethals, J.; Bajek, A.; Dierckens, K.; Bossier, P.; De Geest, B.G.; Vanrompay, D. (2017). Preparation and characterization of alginate microparticles containing a model protein for oral administration in gnotobiotic European sea bass (Dicentrarchus labrax) larvae. Mar. Biotechnol. 19(4): 391-400. https://dx.doi.org/10.1007/s10126-017-9758-4","PeerRev":1},{"BRefID":256688,"RR":"Nguyen Thi Xuan, H.; Baruah, K.; Vanrompay, D.; Bossier, P. (2016). Characterization of phenotype variations of luminescent and non-luminescent variants of Vibrio harveyi wild type and quorum sensing mutants. J. Fish Dis. 39(3): 317-327. https://dx.doi.org/10.1111/jfd.12365","PeerRev":1},{"BRefID":286156,"RR":"Pestana, J.L.T.; Novais, S.C.; Norouzitallab, P.; Vandegehuchte, M.B.; Bossier, P.; De Schamphelaere, K. (2016). Non-lethal heat shock increases tolerance to metal exposure in brine shrimp. Environ. Res. 151: 663-670. https://dx.doi.org/10.1016/j.envres.2016.08.037","PeerRev":1},{"BRefID":283815,"RR":"Yaacob, E.N.; De Geest, B.G.; Goethals, J.; Bajeck, A.; Dierckens, K.; Bossier, P.; Vanrompay, D. (2016). Recombinant ferritin-H induces immunosupression in European sea bass larvae (Dicentrarchus labrax) rather than immunostmulation and protection against Vibrio anguillarum. Fish Shellfish Immunol. 53: 86-86. https://dx.doi.org/10.1016/j.fsi.2016.03.125","PeerRev":1},{"BRefID":283817,"RR":"Yaacob, E.N.; De Geest, B.G.; Goethals, J.; Bajeck, A.; Dierckens, K.; Bossier, P.; Vanrompay, D. (2016). Administration of bacterial heat shock protein 70 to induce a protective innate immune response in European sea bass larvae (Dicentrarchus labrax) against Vibrio anguillarum. Fish Shellfish Immunol. 53: 95-95. https://dx.doi.org/10.1016/j.fsi.2016.04.033","PeerRev":1},{"BRefID":285460,"RR":"Yaacob, E.N.; Vandenbosch, D.; Coenye, T.; Bajek, A.; Vanrompay, D.; Dierckens, K.; Bossier, P. (2016). Drinking activity and microparticle size selection in early post-hatching axenic European sea bass (Dicentrarchus labrax L.) larvae. Aquaculture 463: 37-42. https://dx.doi.org/10.1016/j.aquaculture.2016.05.025","PeerRev":1}],"conferences":null,"datasets":null,"persons":[{"PersID":44507,"Surname":"Casado Simon","Firstname":"Enrique","Initials":null,"DirectorFlag":null,"MarineSciFlag":1,"SpecializedFlag":null,"Function":null},{"PersID":44705,"Surname":"Rwezawula","Firstname":"Philip","Initials":null,"DirectorFlag":null,"MarineSciFlag":1,"SpecializedFlag":null,"Function":null},{"PersID":44762,"Surname":"Vandeputte","Firstname":"Marieke","Initials":null,"DirectorFlag":null,"MarineSciFlag":1,"SpecializedFlag":null,"Function":null}],"pastpers":[{"PersID":39428,"Surname":"Goethals","Firstname":"Jens","Initials":"J.","DirectorFlag":null,"MarineSciFlag":null,"SpecializedFlag":null,"Function":null}],"subpers":null,"projects":null,"urls":[{"URL":"https://www.ugent.be/bw/asae/en/research/immunoanimalbiot","externalID":null,"URLTypeCode":null,"URLType":null}],"pictures":[],"published":null,"affrefs":null,"collections":null,"thesterms":[{"ThesaurusTerm":"Aquaculture","ThestID":181481,"ThesTypID":29,"ThesType":"MOG Topics"},{"ThesaurusTerm":"Biochemistry","ThestID":181483,"ThesTypID":29,"ThesType":"MOG Topics"},{"ThesaurusTerm":"Biotechnology","ThestID":181487,"ThesTypID":29,"ThesType":"MOG Topics"},{"ThesaurusTerm":"Human health","ThestID":181503,"ThesTypID":29,"ThesType":"MOG Topics"},{"ThesaurusTerm":"Molecular biology","ThestID":181511,"ThesTypID":29,"ThesType":"MOG Topics"},{"ThesaurusTerm":"Nutrition","ThestID":181513,"ThesTypID":29,"ThesType":"MOG Topics"}],"taxterms":null,"geoterms":null,"thestermsFRIS":[{"ThesaurusTerm":"Aquaculture","DutchTerm":"Aquacultuur","ThestID":181481,"ThesTypID":29,"ThesType":"MOG Topics","Code":null},{"ThesaurusTerm":"Biochemistry","DutchTerm":"Biochemie","ThestID":181483,"ThesTypID":29,"ThesType":"MOG Topics","Code":null},{"ThesaurusTerm":"Biotechnology","DutchTerm":"Biotechnologie","ThestID":181487,"ThesTypID":29,"ThesType":"MOG Topics","Code":null},{"ThesaurusTerm":"Human health","DutchTerm":"Menselijke gezondheid","ThestID":181503,"ThesTypID":29,"ThesType":"MOG Topics","Code":null},{"ThesaurusTerm":"Molecular biology","DutchTerm":"Moleculaire biologie","ThestID":181511,"ThesTypID":29,"ThesType":"MOG Topics","Code":null},{"ThesaurusTerm":"Nutrition","DutchTerm":"Voeding","ThestID":181513,"ThesTypID":29,"ThesType":"MOG Topics","Code":null}],"nXtins":null,"previns":null,"spcols":[{"SpColID":99,"SpName":"Marine expertise"},{"SpColID":121,"SpName":"Marine expertise: Type: Flemish university"}],"resmessage":"","complete":1,"participantrec":null,"peerrevs":20,"urlmaps":[]}