{"personrec":{"StatusID":1,"PersStatus":null,"Status":"Valid","PersID":27019,"PersName":"Peigneur, Steve","PublicFlag":1,"CheckedFlag":1,"Surname":"Peigneur","Firstname":"Steve","Initials":"S.","AddressedAs":null,"Function":null,"DateLastModified":{"date":"2024-06-04 01:34:08.417000","timezone_type":1,"timezone":"+00:00"},"PersTitle":null,"PersStatusID":null,"AbstractEnglish":null,"AbstractOtherLang":null,"AbstractLangCode":null,"AbstractLangID":null,"AutID":155255,"ND":"2013-01-22","UD":"2023-05-15","ORCID":"0000-0003-0504-5702"},"loaninfo":null,"pictures":[],"institutes":[{"instituterec":{"OrderNr":1,"Acronym":null,"ENFunction":"Marine researcher","InsIDtmp":492,"OrigNameLangCode":"en","OrigNameLangID":15,"FullOrigName":"University of Leuven; Departement Farmaceutische en Farmacologische Wetenschappen; Laboratory for Toxicology and Pharmacology","InsID":492,"Function":"Marine researcher","BeginDay":null,"BeginMonth":null,"BeginYear":null,"Begindate":"","Enddate":"","PIAdrID":153546,"AdrID":111552,"Line1":null,"Line2":null,"Line3":null,"Line4":null,"Phone":null,"GSM":null,"Email":"steve.peigneur@pharm.kuleuven.be","EnvName":"Belgium","EncAddress":"O. & N.2, Herestraat 49B 922, 3000 Leuven, Belgium","FullStandardName":"KU Leuven; Departement Farmaceutische en Farmacologische Wetenschappen; Laboratorium voor Toxicologie en Farmacologie","DirectorFlag":null,"MarineSciFlag":1,"SpecializedFlag":null},"parent":null,"institutes":null,"references":null,"conferences":null,"datasets":null,"persons":null,"pastpers":null,"subpers":null,"projects":null,"urls":null,"pictures":null,"published":null,"affrefs":null,"collections":null,"thesterms":null,"taxterms":null,"geoterms":null,"thestermsFRIS":null,"nXtins":null,"previns":null,"spcols":null,"resmessage":"no id specified","complete":0,"participantrec":null,"peerrevs":null,"urlmaps":null}],"pastins":[],"projects":[],"datasets":null,"references":{"A1":[{"BRefID":367603,"RR":"<b>Depuydt, A.-S.; Patel, P.A.; Toplak, Ž.; Bhat, C.; Vorácová, M.; Eteläinen, I.; Vitulano, F.; Bruun, T.; Lempinen, A.; Hribernik, N.; Mäki-Lohiluoma, E.; Hendrickx, L.; Pinheiro-Junior, E.L.; Tomašic, T.; Mašic, L.P.; Yli-Kauhaluoma, J.; Kiuru, P.; Tytgat, J.; Peigneur, S.</b> (2023). Structure-function studies of sponge-derived compounds on the cardiac CaV3.1 channel. <i>International Journal of Molecular Sciences 24(4)</i>: 3429. <a href=\"https://dx.doi.org/10.3390/ijms24043429\" target=\"_blank\">https://dx.doi.org/10.3390/ijms24043429</a>","AutID":320746,"MonDate":null,"AnaDate":2023,"PeerRev":1,"outputType":"1_A1","OpenAcc":1},{"BRefID":352760,"RR":"<b>An, D.; Pinheiro-Junior, E.L.; Béress, L.; Gladkikh, I.; Leychenko, E.; Undheim, E.A.B.; Peigneur, S.; Tytgat, J.</b> (2022). AsKC11, a Kunitz peptide from <i>Anemonia sulcata</i>, is a novel activator of G protein-coupled inward-rectifier potassium channels. <i>Mar. Drugs 20(2)</i>: 140. <a href=\"https://dx.doi.org/10.3390/md20020140\" target=\"_blank\">https://dx.doi.org/10.3390/md20020140</a>","AutID":256132,"MonDate":null,"AnaDate":2022,"PeerRev":1,"outputType":"1_A1","OpenAcc":1},{"BRefID":362446,"RR":"<b>Kalina, R.S.; Kasheverov, I.E.; Koshelev, S.G.; Sintsova, O.V.; Peigneur, S.; Pinheiro-Junior, E.L.; Popov, R.S.; Chausova, V.; Monastyrnaya, M.M.; Dmitrenok, P.S.; Isaeva, M.P.; Tytgat, J.; Kozlov, S.A.; Kozlovskaya, E.P.; Leychenko, E.V.; Gladkikh, I.N.</b> (2022). Nicotinic acetylcholine receptors are novel targets of APETx-like toxins from the sea anemone <i>Heteractis magnifica</i>. <i>Toxins 14(10)</i>: 697. <a href=\"https://dx.doi.org/10.3390/toxins14100697\" target=\"_blank\">https://dx.doi.org/10.3390/toxins14100697</a>","AutID":223893,"MonDate":null,"AnaDate":2022,"PeerRev":1,"outputType":"1_A1","OpenAcc":1},{"BRefID":362464,"RR":"<b>Kvetkina, A.; Pislyagin, E.; Menchinskaya, E.; Yurchenko, E.; Kalina, R.; Kozlovskiy, S.; Kaluzhskiy, L.; Kim, N.; Peigneur, S.; Tytgat, J.; Ivanov, A.; Ayvazyan, N.; Leychenko, E.; Aminin, D.</b> (2022). Kunitz-type peptides from sea anemones protect neuronal cells against Parkinson's disease inductors via inhibition of ROS production and ATP-induced P2X7 receptor activation. <i>International Journal of Molecular Sciences 23(9)</i>: 5115. <a href=\"https://dx.doi.org/10.3390/ijms23095115\" target=\"_blank\">https://dx.doi.org/10.3390/ijms23095115</a>","AutID":223893,"MonDate":null,"AnaDate":2022,"PeerRev":1,"outputType":"1_A1","OpenAcc":1},{"BRefID":383001,"RR":"<b>Laborde, Q.; Peigneur, S.; Andersson, H.; Tytgat, J.; Jacobsson, E.; Goransson, U.</b> (2022). The toxicity of <span lang=\"NL-BE\" dir=\"ltr\">α</span>-nemertide 1 peptide alanine-mutants from the marine nemertean worm <i>Lineus longissimus</i>. <i>Journal of Peptide Science 28</i>: P004","AutID":223893,"MonDate":null,"AnaDate":2022,"PeerRev":1,"outputType":"1_A1","OpenAcc":0},{"BRefID":352770,"RR":"<b>Pinheiro-Junior, E.L.; Kalina, R.; Gladkikh, I.; Leychenko, E.; Tytgat, J.; Peigneur, S.</b> (2022). A tale of toxin promiscuity: the versatile pharmacological effects of Hcr 1b-2 sea anemone peptide on voltage-gated ion channels. <i>Mar. Drugs 20(2)</i>: 147. <a href=\"https://dx.doi.org/10.3390/md20020147\" target=\"_blank\">https://dx.doi.org/10.3390/md20020147</a>","AutID":256132,"MonDate":null,"AnaDate":2022,"PeerRev":1,"outputType":"1_A1","OpenAcc":1},{"BRefID":361805,"RR":"<b>Schmidt, C.A.; Cooke, I.; Wilson, D.T.; Miller, D.J.; Peigneur, S.; Tytgat, J.; Field, M.; Takjoo, R.; Smout, M.J.; Loukas, A.; Daly, N.L.</b> (2022). Newly discovered peptides from the coral <i>Heliofungia actiniformis</i> show structural and functional diversity. <i>J. Nat. Prod. 85(7)</i>: 1789-1798. <a href=\"https://dx.doi.org/10.1021/acs.jnatprod.2c00325\" target=\"_blank\">https://dx.doi.org/10.1021/acs.jnatprod.2c00325</a>","AutID":373029,"MonDate":null,"AnaDate":2022,"PeerRev":1,"outputType":"1_A1","OpenAcc":0},{"BRefID":361563,"RR":"<b>Wiere, S.; Sugai, C.; Espiritu, M.J.; Aurelio, V.P.; Reyes, C.D.; Yuzon, N.; Whittal, R.M.; Tytgat, J.; Peigneur, S.; Bingham, J.-P.</b> (2022). Research into the bioengineering of a novel α-conotoxin from the milked venom of <i>Conus obscurus</i>. <i>International Journal of Molecular Sciences 23(20)</i>: 12096. <a href=\"https://dx.doi.org/10.3390/ijms232012096\" target=\"_blank\">https://dx.doi.org/10.3390/ijms232012096</a>","AutID":182911,"MonDate":null,"AnaDate":2022,"PeerRev":1,"outputType":"1_A1","OpenAcc":1},{"BRefID":353299,"RR":"<b>Jacobsson, E.; Peigneur, S.; Andersson, H.S.; Laborde, Q.; Strand, M.; Tytgat, J.; Goransson, U.</b> (2021). Functional characterization of the nemertide α family of peptide toxins. <i>J. Nat. Prod. 84(8)</i>: 2121-2128. <a href=\"https://dx.doi.org/10.1021/acs.jnatprod.1c00104\" target=\"_blank\">https://dx.doi.org/10.1021/acs.jnatprod.1c00104</a>","AutID":194833,"MonDate":null,"AnaDate":2021,"PeerRev":1,"outputType":"1_A1","OpenAcc":1},{"BRefID":391565,"RR":"<b>Mitchell, M.L.; Hossain, M.A.; Lin, F.; Pinheiro-Junior, E.L.; Peigneur, S.; Wai, D.C.C.; Delaine, C.; Blyth, A.J.; Forbes, B.E.; Tytgat, J.; Wade, J.D.; Norton, R.S.</b> (2021). Identification, synthesis, conformation and activity of an insulin-like peptide from a sea anemone. <i>Biomolecules 11(12)</i>: 1785. <a href=\"https://dx.doi.org/10.3390/biom11121785\" target=\"_blank\">https://dx.doi.org/10.3390/biom11121785</a>","AutID":223893,"MonDate":null,"AnaDate":2021,"PeerRev":1,"outputType":"1_A1","OpenAcc":1},{"BRefID":337296,"RR":"<b>Sintsova, O.; Gladkikh, I.; Monastyrnaya, M.; Tabakmakher, V.; Yurchenko, E.; Menchinskaya, E.; Pislyagin, E.; Andreev, Y.; Kozlov, S.; Peigneur, S.; Tytgat, J.; Aminin, D.; Kozlovskaya, E.; Leychenko, E.</b> (2021). Sea anemone Kunitz-type peptides demonstrate neuroprotective activity in the 6-hydroxydopamine induced neurotoxicity model. <i>Biomedicines 9(3)</i>: 283. <a href=\"https://hdl.handle.net/10.3390/biomedicines9030283\" target=\"_blank\">https://hdl.handle.net/10.3390/biomedicines9030283</a>","AutID":223893,"MonDate":null,"AnaDate":2021,"PeerRev":1,"outputType":"1_A1","OpenAcc":1},{"BRefID":337584,"RR":"<b>Gladkikh, I.; Peigneur, S.; Sintsova, O.; Pinheiro-Junior, E.L.; Klimovich, A.; Menshov, A.; Kalinovsky, A.; Isaeva, M.; Monastyrnaya, M.; Kozlovskaya, E.; Tytgat, J.; Leychenko, E.</b> (2020). Kunitz-type peptides from the sea anemone <i>Heteractis crispa</i> demonstrate potassium channel blocking and anti-inflammatory activities. <i>Biomedicines 8(11)</i>: 473. <a href=\"https://hdl.handle.net/10.3390/biomedicines8110473\" target=\"_blank\">https://hdl.handle.net/10.3390/biomedicines8110473</a>","AutID":223893,"MonDate":null,"AnaDate":2020,"PeerRev":1,"outputType":"1_A1","OpenAcc":1},{"BRefID":338045,"RR":"<b>Kalina, R.S.; Peigneur, S.; Zelepuga, E.A.; Dmitrenok, P.S.; Kvetkina, A.N.; Kim, N.Y.; Leychenko, E.V.; Tytgat, J.; Kozlovskaya, E.P.; Monastyrnaya, M.M.; Gladkikh, I.N.</b> (2020). New insights into the type II toxins from the sea anemone <i>Heteractis crispa</i>. <i>Toxins 12(1)</i>: 44. <a href=\"https://hdl.handle.net/10.3390/toxins12010044\" target=\"_blank\">https://hdl.handle.net/10.3390/toxins12010044</a>","AutID":223893,"MonDate":null,"AnaDate":2020,"PeerRev":1,"outputType":"1_A1","OpenAcc":1},{"BRefID":337573,"RR":"<b>Kalina, R.S.; Peigneur, S.; Gladkikh, I.N.; Dmitrenok, P.S.; Kim, N.Y.; Leychenko, E.V.; Monastyrnaya, M.M.; Tytgat, J.; Kozlovskaya, E.P.</b> (2020). New sea anemone toxin RTX-VI selectively modulates voltage-gated sodium channels. <i>Doklady Biochemistry and Biophysics 495(1)</i>: 292-295. <a href=\"https://hdl.handle.net/10.1134/S1607672920060071\" target=\"_blank\">https://hdl.handle.net/10.1134/S1607672920060071</a>","AutID":368527,"MonDate":null,"AnaDate":2020,"PeerRev":1,"outputType":"1_A1","OpenAcc":0},{"BRefID":337946,"RR":"<b>Kvetkina, A.; Leychenko, E.; Chausova, V.; Zelepuga, E.; Chernysheva, N.; Guzev, K.; Pislyagin, E.; Yurchenko, E.; Menchinskaya, E.; Aminin, D.; Kaluzhskiy, L.; Ivanov, A.; Peigneur, S.; Tytgat, J.; Kozlovskaya, E.; Isaeva, M.</b> (2020). A new multigene HCIQ subfamily from the sea anemone <i>Heteractis crispa</i> encodes Kunitz-peptides exhibiting neuroprotective activity against 6-hydroxydopamine. <i>NPG Scientific Reports 10(1)</i>: 4205. <a href=\"https://hdl.handle.net/10.1038/s41598-020-61034-x\" target=\"_blank\">https://hdl.handle.net/10.1038/s41598-020-61034-x</a>","AutID":223893,"MonDate":null,"AnaDate":2020,"PeerRev":1,"outputType":"1_A1","OpenAcc":1},{"BRefID":337540,"RR":"<b>Schmidt, C.A.; Wilson, D.T.; Cooke, I.; Potriquet, J.; Tungatt, K.; Muruganandah, V.; Boote, C.; Kuek, F.; Miles, J.J.; Kupz, A.; Ryan, S.; Loukas, A.; Bansal, P.S.; Takjoo, R.; Miller, D.J.; Peigneur, S.; Tytgat, J.; Daly, N.L.</b> (2020). Identification and characterization of a peptide from the stony coral <i>Heliofungia actiniformis</i>. <i>J. Nat. Prod. 83(11)</i>: 3454-3463. <a href=\"https://hdl.handle.net/10.1021/acs.jnatprod.0c00981\" target=\"_blank\">https://hdl.handle.net/10.1021/acs.jnatprod.0c00981</a>","AutID":373029,"MonDate":null,"AnaDate":2020,"PeerRev":1,"outputType":"1_A1","OpenAcc":0},{"BRefID":338100,"RR":"<b>Andersson, H.S.; Jacobsson, E.; Strand, M.; Peigneur, S.; Lebbe, E.K.M.; Rosengren, K.J.; Goransson, U.; Tytgat, J.</b> (2019). α-nemertides, a novel family of marine peptide neurotoxins from ribbon worms. <i>Toxicon 158(S1)</i>: S38-S39. <a href=\"https://hdl.handle.net/10.1016/j.toxicon.2018.10.136\" target=\"_blank\">https://hdl.handle.net/10.1016/j.toxicon.2018.10.136</a>","AutID":194833,"MonDate":null,"AnaDate":2019,"PeerRev":1,"outputType":"1_A1","OpenAcc":0},{"BRefID":322938,"RR":"<b>Elnahriry, K.A.; Wai, D.C.C.; Krishnarjuna, B.; Badawy, N.N.; Chittoor, B.; MacRaild, C.A.; Williams-Noonan, B.J.; Surm, J.M.; Chalmers, D.K.; Zhang, A.H.; Peigneur, S.; Mobli, M.; Tytgat, J.; Prentis, P.; Norton, R.S.</b> (2019). Structural and functional characterisation of a novel peptide from the Australian sea anemone <i>Actinia tenebrosa</i>. <i>Toxicon 168</i>: 104-112. <a href=\"https://dx.doi.org/10.1016/j.toxicon.2019.07.002\" target=\"_blank\">https://dx.doi.org/10.1016/j.toxicon.2019.07.002</a>","AutID":320746,"MonDate":null,"AnaDate":2019,"PeerRev":1,"outputType":"1_A1","OpenAcc":0},{"BRefID":338101,"RR":"<b>Gladkikh, I.; Kalina, R.; Sinsova, O.; Kvetkina, A.; Peigneur, S.; Koshelev, S.; Kim, N.; Monastyrnaya, M.; Kozlov, S.; Tytgat, J.; Kozlovskaya, E.</b> (2019). New Kv, NAv, and ASIC channel toxins from the sea anemone <i>Heteractis crispa</i>. <i>Toxicon 158(S1)</i>: S48-S48. <a href=\"https://hdl.handle.net/10.1016/j.toxicon.2018.10.168\" target=\"_blank\">https://hdl.handle.net/10.1016/j.toxicon.2018.10.168</a>","AutID":223893,"MonDate":null,"AnaDate":2019,"PeerRev":1,"outputType":"1_A1","OpenAcc":0},{"BRefID":338092,"RR":"<b>Kalina, R.; Gladkikh, I.; Peigneur, S.; Dmitrenok, P.; Zelepuga, E.; Monastyrnaya, M.; Kozlovskaya, E.</b> (2019). Type II toxins from sea anemone <i>Heteractis crispa</i> with various effects on activation and inactivation of voltage-gated sodium channels. <i>Toxicon 159(S1)</i>: S18-S18. <a href=\"https://hdl.handle.net/10.1016/j.toxicon.2018.11.376\" target=\"_blank\">https://hdl.handle.net/10.1016/j.toxicon.2018.11.376</a>","AutID":223893,"MonDate":null,"AnaDate":2019,"PeerRev":1,"outputType":"1_A1","OpenAcc":0},{"BRefID":310368,"RR":"<b>Peigneur, S.; Cheneval, O.; Maiti, M.; Leipold, E.; Heinemann, S.H.; Lescrinier, E.; Herdewijn, P.; de Lima, M.E.; Craik, D.J.; Schroeder, C.I.; Tytgat, J.</b> (2019). Where cone snails and spiders meet: design of small cyclic sodium-channel inhibitors. <i>FASEB J. 33(3)</i>: 3693-3703. <a href=\"https://dx.doi.org/10.1096/fj.201801909R\" target=\"_blank\">https://dx.doi.org/10.1096/fj.201801909R</a>","AutID":373029,"MonDate":null,"AnaDate":2019,"PeerRev":1,"outputType":"1_A1","OpenAcc":0},{"BRefID":322986,"RR":"<b>Peigneur, S.; Devi, P.; Seldeslachts, A.; Ravichandran, S.; Quinton, L.; Tytgat, J.</b> (2019). Structure-function elucidation of a new α-conotoxin, MiIIA, from <i>Conus milneedwardsi</i>. <i>Mar. Drugs 17(9)</i>: 535. <a href=\"https://dx.doi.org/10.3390/md17090535\" target=\"_blank\">https://dx.doi.org/10.3390/md17090535</a>","AutID":256132,"MonDate":null,"AnaDate":2019,"PeerRev":1,"outputType":"1_A1","OpenAcc":1},{"BRefID":322982,"RR":"<b>Sachkova, M.Y.; Singer, S.A.; Macrander, J.; Reitzel, A.M.; Peigneur, S.; Tytgat, J.; Moran, Y.</b> (2019). The birth and death of toxins with distinct functions: a case study in the sea anemone <i>Nematostella</i>. <i>Mol. Biol. Evol. 36(9)</i>: 2001-2012. <a href=\"https://dx.doi.org/10.1093/molbev/msz132\" target=\"_blank\">https://dx.doi.org/10.1093/molbev/msz132</a>","AutID":408828,"MonDate":null,"AnaDate":2019,"PeerRev":1,"outputType":"1_A1","OpenAcc":1},{"BRefID":322918,"RR":"<b>Sintsova, O.; Kalinovskii, A.; Gladkikh, I.; Zelepuga, E.; Monastyrnaya, M.; Kim, N.; Shevchenko, L.; Peigneur, S.; Tytgat, J.; Kozlovskaya, E.; Leychenko, E.</b> (2019). Magnificamide, a β-defensin-like peptide from the mucus of the sea anemone <i>Heteractis magnifica</i>, is a strong inhibitor of mammalian α-amylases. <i>Mar. Drugs 17(10)</i>: 542. <a href=\"https://dx.doi.org/10.3390/md17100542\" target=\"_blank\">https://dx.doi.org/10.3390/md17100542</a>","AutID":223893,"MonDate":null,"AnaDate":2019,"PeerRev":1,"outputType":"1_A1","OpenAcc":1},{"BRefID":338093,"RR":"<b>Zelepuga, E.; Gladkikh, I.; Peigneur, S.; Tytgat, J.; Monastyrnaya, M.; Kozlovskaya, E.</b> (2019). The Kunitz-type HCRG peptides from the sea anemone <i>Heteractis crispa</i> possess Kv channel toxicity. <i>Toxicon 159(S1)</i>: S26-S27. <a href=\"https://hdl.handle.net/10.1016/j.toxicon.2018.11.408\" target=\"_blank\">https://hdl.handle.net/10.1016/j.toxicon.2018.11.408</a>","AutID":223893,"MonDate":null,"AnaDate":2019,"PeerRev":1,"outputType":"1_A1","OpenAcc":0},{"BRefID":301264,"RR":"<b>Jacobsson, E.; Andersson, H.S.; Strand, M.; Peigneur, S.; Eriksson, C.; Loden, H.; Shariatgorji, M.; Andren, P.E.; Lebbe, E.K.M.; Rosengren, K.J.; Tytgat, J.; Goransson, U.</b> (2018). Peptide ion channel toxins from the bootlace worm, the longest animal on Earth. <i>NPG Scientific Reports 8</i>: 10. <a href=\"https://dx.doi.org/10.1038/s41598-018-22305-w\" target=\"_blank\">https://dx.doi.org/10.1038/s41598-018-22305-w</a>","AutID":194833,"MonDate":null,"AnaDate":2018,"PeerRev":1,"outputType":"1_A1","OpenAcc":1},{"BRefID":293586,"RR":"<b>Krishnarjuna, B.; MacRaild, C.A.; Sunanda, P.; Morales, R.A.V.; Peigneur, S.; Macrander, J.; Yu, H.H.; Daly, M.; Raghothama, S.; Dhawan, V.; Chauhan, S.; Tytgat, J.; Pennington, M.W.; Norton, R.S.</b> (2018). Structure, folding and stability of a minimal homologue from <i>Anemonia sulcata</i> of the sea anemone potassium channel blocker ShK. <i>Peptides (New York, NY : 1980) 99</i>: 169-178. <a href=\"https://dx.doi.org/10.1016/j.peptides.2017.10.001\" target=\"_blank\">https://dx.doi.org/10.1016/j.peptides.2017.10.001</a>","AutID":320746,"MonDate":null,"AnaDate":2018,"PeerRev":1,"outputType":"1_A1","OpenAcc":0},{"BRefID":308013,"RR":"<b>Krishnarjuna, B.; MacRaild, C.A.; Sunanda, P.; Morales, R.A.V.; Peigneur, S.; Macrander, J.; Yu, H.H.; Daly, M.; Raghothama, S.; Chauhan, S.; Tytgat, J.; Pennington, M.W.; Norton, R.S.</b> (2018). Corrigendum to“Structure, folding and stability of a minimal homologue from <i>Anemonia sulcata</i> of the sea anemone potassium channel blocker ShK”[Peptides 99 (2018) 169–178]. <i>Peptides (New York, NY : 1980) 101</i>: 234-234. <a href=\"https://dx.doi.org/10.1016/j.peptides.2018.01.008\" target=\"_blank\">https://dx.doi.org/10.1016/j.peptides.2018.01.008</a>","AutID":320746,"MonDate":null,"AnaDate":2018,"PeerRev":1,"outputType":"1_A1","OpenAcc":1},{"BRefID":310451,"RR":"<b>Krishnarjuna, B.; Villegas-Moreno, J.; Mitchell, M.L.; Csoti, A.; Peigneur, S.; Amero, C.; Pennington, M.W.; Tytgat, J.; Panyi, G.; Norton, R.S.</b> (2018). Synthesis, folding, structure and activity of a predicted peptide from the sea anemone <i>Oulactis</i> sp. with an ShKT fold. <i>Toxicon 150</i>: 50-59. <a href=\"https://dx.doi.org/10.1016/j.toxicon.2018.05.006\" target=\"_blank\">https://dx.doi.org/10.1016/j.toxicon.2018.05.006</a>","AutID":320746,"MonDate":null,"AnaDate":2018,"PeerRev":1,"outputType":"1_A1","OpenAcc":0},{"BRefID":307951,"RR":"<b>Kvetkina, A.N.; Leychenko, E.V.; Yurchenko, E.A.; Pislyagin, E.A.; Peigneur, S.; Tytgat, Y.; Isaeva, M.P.; Aminin, D.L.; Kozlovskaya, E.P.</b> (2018). A new Iq-peptide of the Kunitz type from the <i>Heteractis magnifica</i> sea anemone exhibits neuroprotective activity in a model of Alzheimer's disease. <i>Russian Journal of Bioorganic Chemistry 44(4)</i>: 416-423. <a href=\"https://dx.doi.org/10.1134/S106816201804012X\" target=\"_blank\">https://dx.doi.org/10.1134/S106816201804012X</a>","AutID":368540,"MonDate":null,"AnaDate":2018,"PeerRev":1,"outputType":"1_A1","OpenAcc":0},{"BRefID":310427,"RR":"<b>Madio, B.; Peigneur, S.; Chin, Y.K.Y.; Hamilton, B.; Henriques, S.T.; Smith, J.J.; Cristofori-Armstrong, B.; Dekan, Z.; Boughton, B.A.; Alewood, P.F.; Tytgat, J.; King, G.F.; Undheim, E.A.B.</b> (2018). PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold. <i>Cellular and molecular life sciences 75(24)</i>: 4511-4524. <a href=\"https://dx.doi.org/10.1007/s00018-018-2897-6\" target=\"_blank\">https://dx.doi.org/10.1007/s00018-018-2897-6</a>","AutID":320746,"MonDate":null,"AnaDate":2018,"PeerRev":1,"outputType":"1_A1","OpenAcc":0},{"BRefID":307906,"RR":"<b>Orts, D.J.B.; Peigneur, S.; Silva-Goncalves, L.C.; Arcisio-Miranda, M.; Bicudo, J.E.P.W.; Tytgat, J.</b> (2018). AbeTx1 is a novel sea anemone toxin with a dual mechanism of action on Shaker-type K+ channels activation. <i>Mar. 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Pc16a, the first characterized peptide from <i>Conus pictus</i> venom, shows a novel disulfide connectivity. <i>Peptides (New York, NY : 1980) 34(1)</i>: 106-113. <a href=\"http://dx.doi.org/10.1016/j.peptides.2011.10.026\" target=\"_blank\">dx.doi.org/10.1016/j.peptides.2011.10.026</a>","AutID":155255,"MonDate":null,"AnaDate":2012,"PeerRev":1,"outputType":"1_A1","OpenAcc":0},{"BRefID":257693,"RR":"<b>Cuypers, E.; Peigneur, S.; Debaveye, S.; Shiomi, K.; Tytgat, J.</b> (2011). TRPV1 channel as new target for marine toxins: Example of gigantoxin I, a sea anemone toxin acting via modulation of the PLA<sub>2</sub> pathway. <i>Acta Chim. Slov. 58(4)</i>: 735-741","AutID":226563,"MonDate":null,"AnaDate":2011,"PeerRev":1,"outputType":"1_A1","OpenAcc":1},{"BRefID":220930,"RR":"<b>Peigneur, S.; Billen, B.; Derua, R.; Waelkens, E.; Debaveye, S.; Béress, L.; Tytgat, J.</b> (2011). 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The mechanism of action of microalgal toxins interacting with Na<sub>v</sub> and K<i>v</i> channels, <b><i>in</i></b>: Rossini, G.P. (Ed.) <i>Toxins and biologically active compounds from microalgae: Volume 2. Biological effects and risk management.</i> pp. 3-34","AutID":190442,"MonDate":null,"AnaDate":2014,"PeerRev":0,"outputType":"4_BookChap","OpenAcc":0}],"Abstr":[{"BRefID":223682,"RR":"<b>Peigneur, S.; Béress, L.; Möller, C.; Marí, F.; Forssmann, W.-G.; Tytgat, J.</b> (2013). Sea anemone toxins: insecticides and painkillers of the future?, <b><i>in</i></b>: Mees, J. <i>et al.</i> (Ed.) <i>Marine biotechnology in the European research area: Challenges and opportunities for Europe. Final CSA MarineBiotech Conference. Royal Flemish Academy of Belgium for Science and the Arts, Brussels, Belgium, 11-12 March 2013. VLIZ Special Publication,</i> 64: pp. 7","AutID":159365,"MonDate":null,"AnaDate":2013,"PeerRev":0,"outputType":"6_Abstr","OpenAcc":1}],"Report":[{"BRefID":355586,"RR":"<b>De Raedemaecker, F.; Sandra, M.; Goeminne, G.; Tytgat, J.; Coenye, T.; Devriese, L.; Bicalho, K.; Vandersyppe, S.; Desmet, S.; Bernaerts, H.; Peigneur, S.; Van Vlieberghe, W.; Loosvelt , L.</b> (2022). Final report. D5.1. PROspection for BIOactive compounds in the North Sea. D 5.1. Flanders Marine Institute (VLIZ): Oostende.  ","AutID":372280,"MonDate":2022,"AnaDate":null,"PeerRev":0,"outputType":"7_Report","OpenAcc":1}],"ThesisPromotor":[{"BRefID":321735,"RR":"<b>Seldeslachts, A.</b> (2019). Novel α-conotoxin targeting nicotinic acetylcholine receptor as selective pharmacological tool in drug development. Ir Thesis. 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