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Voltage-sensor conformation shapes the intra-membrane drug binding site that determines gambierol affinity in Kv channels. <i>Neuropharmacology 107</i>: 160-167. <a href=\"https://dx.doi.org/10.1016/j.neuropharm.2016.03.010\" target=\"_blank\">https://dx.doi.org/10.1016/j.neuropharm.2016.03.010</a>","AutID":233546,"MonDate":null,"AnaDate":2016,"PeerRev":1,"outputType":"1_A1","OpenAcc":0},{"BRefID":285471,"RR":"<b>Martínez-Morales, E.; Kopljar, I.; Rainier, J.D.; Tytgat, J.; Snyders, D.J.; Labro, A.J.</b> (2016). Gambierol and n-alkanols inhibit <i>Shaker</i> Kv channel via distinct binding sites outside the K+ pore. <i>Toxicon 120</i>: 57-60. <a href=\"https://dx.doi.org/10.1016/j.toxicon.2016.07.017\" target=\"_blank\">https://dx.doi.org/10.1016/j.toxicon.2016.07.017</a>","AutID":256481,"MonDate":null,"AnaDate":2016,"PeerRev":1,"outputType":"1_A1","OpenAcc":0},{"BRefID":257361,"RR":"<b>Kopljar, I.; Labro, A.J.; de Block, T.; Rainier, J.; Tytgat, J.; Snyders, D.J.</b> (2013). The ladder-shaped polyether toxin gambierol anchors the gating machinery of Kv3.1 channels in the resting state. <i>J. Gen. Physiol. 141(3)</i>: 359-369. <a href=\"https://dx.doi.org/10.1085/jgp.201210890\" target=\"_blank\">https://dx.doi.org/10.1085/jgp.201210890</a>","AutID":233546,"MonDate":null,"AnaDate":2013,"PeerRev":1,"outputType":"1_A1","OpenAcc":0},{"BRefID":239254,"RR":"<b>Stas, J.; Kopljar, I.; Labro, A.; Peigneur, S.; Zaharenko, A.J.; Tytgat, J.; Snyders, D.J.</b> (2013). A gating modulator peptide toxin for <i>Shaker</i>-type K<sub>v</sub>1 channels derived from the sea anemone <i>Bunodosoma cangicum</i>. <i>Biophys. J. 104(2)</i>: 125A-125A","AutID":183124,"MonDate":null,"AnaDate":2013,"PeerRev":1,"outputType":"1_A1","OpenAcc":0},{"BRefID":238482,"RR":"<b>Kopljar, I.; Labro, A.J.; Rainier, J.D.; Tytgat, J.; Snyders, D.J.</b> (2012). Voltage sensor trapping in voltage-gated K-channels by the marine neurotoxin Gambierol. <i>Toxicon 60(2)</i>: 150-151. <a href=\"http://dx.doi.org/10.1016/j.toxicon.2012.04.111\" target=\"_blank\">dx.doi.org/10.1016/j.toxicon.2012.04.111</a>","AutID":180795,"MonDate":null,"AnaDate":2012,"PeerRev":1,"outputType":"1_A1","OpenAcc":0},{"BRefID":220937,"RR":"<b>Kopljar, I.; Labro, A.J.; Cuypers, E.; Johnson, H.W.B.; Rainier, J.D.; Tytgat, J.; Snyders, D.J.</b> (2009). A polyether biotoxin binding site on the lipid-exposed face of the pore domain of Kv channels revealed by the marine toxin gambierol. <i>Proc. Natl. Acad. Sci. U.S.A. 106(24)</i>: 9896-9901. <a href=\"http://dx.doi.org/10.1073/pnas.0812471106\" target=\"_blank\">http://dx.doi.org/10.1073/pnas.0812471106</a>","AutID":233546,"MonDate":null,"AnaDate":2009,"PeerRev":1,"outputType":"1_A1","OpenAcc":1},{"BRefID":258043,"RR":"<b>Cuypers, E.; Abdel-Mottaleb, Y.; Kopljar, I.; Rainier, J.; Raes, A.L.; Snyders, D.J.; Tytgat, J.</b> (2008). Gambierol, a toxin produced by the dinoflagellate <i>Gambierdiscus toxicus</i>, is a potent blocker of voltage-gated potassium channels. <i>Toxicon 51(6)</i>: 974-983. <a href=\"https://dx.doi.org/10.1016/j.toxicon.2008.01.004\" target=\"_blank\">https://dx.doi.org/10.1016/j.toxicon.2008.01.004</a>","AutID":228605,"MonDate":null,"AnaDate":2008,"PeerRev":1,"outputType":"1_A1","OpenAcc":0}],"BookChap":[{"BRefID":243515,"RR":"<b>Kopljar, I.; Peigneur, S.; Snyders, D.J.; Tytgat, J.</b> (2014). The mechanism of action of microalgal toxins interacting with Na<sub>v</sub> and K<i>v</i> channels, <b><i>in</i></b>: Rossini, G.P. (Ed.) <i>Toxins and biologically active compounds from microalgae: Volume 2. Biological effects and risk management.</i> pp. 3-34","AutID":155163,"MonDate":null,"AnaDate":2014,"PeerRev":0,"outputType":"4_BookChap","OpenAcc":0}]},"urls":[{"URL":"https://orcid.org/0000-0001-7142-6672","externalID":"0000-0001-7142-6672","URLTypeCode":"ORCID","URLType":"ORCID"},{"URL":"www.researcherid.com/rid/A-2713-2013","externalID":"A-2713-2013","URLTypeCode":"ResearcherID","URLType":"ResearcherID"}],"spcols":null,"thesterms":null,"taxterms":null,"pub":1,"newses":{"SesID":11244,"LoginName":"VLIZ2000\\kristin","LoginID":15,"DD":"2004-02-17"},"updses":{"SesID":15654,"LoginName":"VLIZ2000\\kristin","LoginID":15,"DD":"2004-12-09"},"urlmaps":[],"resmessage":"no id specified","complete":1}
