{"projectrec":{"ProID":118,"StandardTitle":"Molecular dynamics of the absorption, accumulation and elimination of metals in marine organisms from the North Sea","OrigTitle":null,"Acronym":null,"AbstractEnglish":"Some metals are essential for the proper functioning of biological systems.\r\nThese metals are required in only extremely low concentrations, and the limit between what is necessary and what is toxic is often very thin. Some marine organisms possess regulating mechanisms to control the absorption and elimination of specific essential metals.\r\n\r\nThis study is designed to gain insight into the molecular mechanisms of the absorption, accumulation and elimination of several metals (Cd, Hg and Zn) in invertebrates from the marine environment, especially in the common shrimp, Crangon crangon.\r\n\r\nAttention will be devoted to three aspects in particular :\r\n\r\n(1) the impact of the chemical speciation of the metal and other environmental factors on their absorption by living organisms;\r\n\r\n(2) the transport of metals from the exchange surfaces to the various tissues of the organisms (role of metallothioneines and other metal-binding proteins);\r\n\r\n(3) kinetics of the accumulation and elimination of metals in organisms in relation to the intra- and extra-cellular complexation of metals.","AbstractOtherLang":null,"DateLastModified":{"date":"2025-07-02 08:33:20.809226","timezone_type":1,"timezone":"+02:00"},"ParentProID":1449,"BeginYear":1992,"EndYear":1996,"BMonth":10,"EMonth":9,"BeginMonth":"October","EndMonth":"September","OrigTitleLangCode":null,"OrigTitleLangID":null,"OrigTitleLangNL":null,"OrigTitleLang":null,"OtherAbstractLangCode":null,"OtherAbstractLangID":null,"OtherAbstractLang":null,"OtherAbstractLangNL":null,"Progress":"Completed","ProgressNL":"Afgelopen","PublicFlag":1,"CheckedFlag":0,"ND":"2003-11-26","UD":"2007-04-03","DMPFlag":0,"Budget":null,"BudgetCurrency":null},"parent":{"ProID":1449,"Acronym":"IMPULS","StandardTitle":"Impulsprogramme \"Marine Sciences\""},"persons":null,"projects":null,"events":null,"datasets":null,"institutes":[{"instituterec":{"Acronym":null,"ProPartID":186,"PublicFlag":1,"OrigNameLangCode":"en","OrigNameLangID":15,"FullOrigName":"University of Antwerp; Faculty of Pharmaceutical, Biomedical and Veterinary Sciences; Department of Biochemistry and Biotechnology; Protein Chemistry Research Group","Line1":"Campus Drie Eiken","Line2":"Universiteitsplein 1","Line3":"2610 Wilrijk","Line4":null,"InsID":1603,"FullStandardName":"Universiteit Antwerpen; Faculteit Farmaceutische, Biomedische en Diergeneeskundige Wetenschappen; Departement Biochemie en Biotechnologie; Onderzoeksgroep Eiwitchemie","Role":null,"RoleID":null,"EncAddress":"Campus Drie Eiken, Universiteitsplein 1, 2610 Wilrijk, Belgium"},"parent":null,"institutes":null,"references":null,"conferences":null,"datasets":null,"persons":[{"Surname":"Moens","Firstname":"Luc","Initials":"L.","LeaderFlag":0,"PersID":151,"Role":"Promotor","RoleID":8,"PastInstitute":0,"BeginDay":null,"BeginMonth":null,"BeginYear":null,"EndDay":null,"EndMonth":null,"EndYear":null}],"pastpers":null,"subpers":null,"projects":null,"urls":null,"pictures":null,"published":null,"affrefs":null,"collections":null,"thesterms":null,"taxterms":null,"geoterms":null,"thestermsFRIS":null,"nXtins":null,"previns":null,"spcols":null,"resmessage":"no id specified","complete":0,"participantrec":null,"peerrevs":null,"urlmaps":null},{"instituterec":{"Acronym":"SPHERE","ProPartID":187,"PublicFlag":1,"OrigNameLangCode":"en","OrigNameLangID":15,"FullOrigName":"University of Antwerp; Faculty of Sciences; Department of Biology; Research group Systemic Physiological and\r\nEcotoxicological Research","Line1":"Campus Middelheim","Line2":"Groenenborgerlaan 171 - Gebouw U","Line3":"2020 Antwerpen","Line4":null,"InsID":108,"FullStandardName":"Universiteit Antwerpen; Faculteit Wetenschappen; Departement Biologie; Onderzoeksgroep Systemisch Fysiologisch en Ecotoxicologisch Onderzoek","Role":null,"RoleID":null,"EncAddress":"Campus Middelheim, Groenenborgerlaan 171 - Gebouw U, 2020 Antwerpen, Belgium"},"parent":null,"institutes":null,"references":null,"conferences":null,"datasets":null,"persons":[{"Surname":"Decleir","Firstname":"Walter","Initials":"W.","LeaderFlag":0,"PersID":149,"Role":"Promotor","RoleID":8,"PastInstitute":null,"BeginDay":null,"BeginMonth":null,"BeginYear":null,"EndDay":null,"EndMonth":null,"EndYear":null},{"Surname":"Blust","Firstname":"Ronny","Initials":"R.","LeaderFlag":0,"PersID":201,"Role":null,"RoleID":null,"PastInstitute":1,"BeginDay":null,"BeginMonth":null,"BeginYear":null,"EndDay":null,"EndMonth":null,"EndYear":null}],"pastpers":null,"subpers":null,"projects":null,"urls":null,"pictures":null,"published":null,"affrefs":null,"collections":null,"thesterms":null,"taxterms":null,"geoterms":null,"thestermsFRIS":null,"nXtins":null,"previns":null,"spcols":null,"resmessage":"no id specified","complete":0,"participantrec":null,"peerrevs":null,"urlmaps":null},{"instituterec":{"Acronym":"BELSPO","ProPartID":5213,"PublicFlag":1,"OrigNameLangCode":"nl","OrigNameLangID":41,"FullOrigName":"Federaal Wetenschapsbeleid","Line1":"WTC III - Simon Bolivarlaan 30","Line2":"1000 Brussel","Line3":null,"Line4":null,"InsID":120,"FullStandardName":"Belgian Science Policy","Role":"Sponsor","RoleID":3,"EncAddress":"WTC III - Simon Bolivarlaan 30, 1000 Brussel, Belgium"},"parent":null,"institutes":null,"references":null,"conferences":null,"datasets":null,"persons":[],"pastpers":null,"subpers":null,"projects":null,"urls":null,"pictures":null,"published":null,"affrefs":null,"collections":null,"thesterms":null,"taxterms":null,"geoterms":null,"thestermsFRIS":null,"nXtins":null,"previns":null,"spcols":null,"resmessage":"no id specified","complete":0,"participantrec":null,"peerrevs":null,"urlmaps":null}],"refs":null,"urls":null,"thesterms":[{"ThesaurusTerm":"Absorption (chemistry)","ThestID":14,"ThesTypID":1,"ThesType":"ASFA Thesaurus List","OrigThesTerm":"Absorption (chemistry)","DutchTerm":null,"Code":null},{"ThesaurusTerm":"Accumulation","ThestID":50,"ThesTypID":1,"ThesType":"ASFA Thesaurus List","OrigThesTerm":"Accumulation","DutchTerm":"Accumulatie","Code":"c_e159fd1f"},{"ThesaurusTerm":"ANE, North Sea","ThestID":182108,"ThesTypID":34,"ThesType":"ASFA Geoterms","OrigThesTerm":"ANE, North Sea","DutchTerm":null,"Code":null},{"ThesaurusTerm":"Chemical speciation","ThestID":1500,"ThesTypID":1,"ThesType":"ASFA Thesaurus List","OrigThesTerm":"Chemical speciation","DutchTerm":"Chemische speciatie","Code":null},{"ThesaurusTerm":"Marine invertebrates","ThestID":5007,"ThesTypID":1,"ThesType":"ASFA Thesaurus List","OrigThesTerm":"Marine invertebrates","DutchTerm":"Mariene invertebraten","Code":"c_4672a815"},{"ThesaurusTerm":"Metallothioneins","ThestID":9559,"ThesTypID":1,"ThesType":"ASFA Thesaurus List","OrigThesTerm":"Metallothioneins","DutchTerm":null,"Code":null},{"ThesaurusTerm":"Trace metals","ThestID":8674,"ThesTypID":1,"ThesType":"ASFA Thesaurus List","OrigThesTerm":"Trace metals","DutchTerm":"Sporenmetalen","Code":"c_909f18e4"}],"taxterms":[{"TaxTerm":"Crangon crangon (Linnaeus, 1758) [Brown shrimp]","AphiaID":107552,"OrigTaxTerm":"Crangon crangon (Linnaeus, 1758)","DutchTerm":"Gewone garnaal"}],"geoterms":[{"GeoTerm":"North Sea","GeoObjectID":2350,"OrigGeoTerm":"North Sea","DutchTerm":"Noordzee"}],"funderids":[{"FunderID":"MS/A1/01","ThestID":181476,"FunderType":"Other contract id"}],"othtermsFRIS":null,"pictures":[],"spcols":[{"SpColID":38,"SpName":"Marine Biodiversity and Ecosystem Functioning"}],"resmessage":"","complete":1}