{"projectrec":{"ProID":2923,"StandardTitle":"Een fysiologisch gebaseerd farmacokinetisch model voor de opstapeling  van microcontaminanten en immunologische effecten in gewone zeehonden (Phoca vitulina) en bruinvissen (Phocoena phocoena)","OrigTitle":null,"Acronym":null,"AbstractEnglish":null,"AbstractOtherLang":"Doelstellingen: Ontwikkeling van een fysiologisch (bioenergetisch) model voor de lange termijn opname en accumulatie van prioritaire microcontaminanten door de zeehond. Evaluatie van het model door vergelijking van voorspellingen met analyseresultaten van microcontaminanten in bloed en biopsie (levende dieren) en andere weefsels (dode dieren). Bepaling van conditie van zeehonden aan de hand van algemene conditie-indices en meer specifieke indicatoren van homeostase en stress door analyse van bloedstalen met bijzondere aandacht voor endocriene effecten en immuniteit. Leggen van verbanden tussen blootstelling, accumulatie en effecten. Door vergelijking van de resultaten bekomen uit analyse van dieren uit verschillende gebieden en gebruikmakende van multi-variate technieken zullen we ook nagaan of het mogelijk is de oorzaak van de effecten op eenduidige wijze te identificeren.","DateLastModified":{"date":"2024-05-06 10:25:46.257000","timezone_type":1,"timezone":"+00:00"},"ParentProID":null,"BeginYear":2008,"EndYear":2009,"BMonth":1,"EMonth":12,"BeginMonth":"January","EndMonth":"December","OrigTitleLangCode":null,"OrigTitleLangID":null,"OrigTitleLangNL":null,"OrigTitleLang":null,"OtherAbstractLangCode":"nl","OtherAbstractLangID":41,"OtherAbstractLang":"Dutch","OtherAbstractLangNL":"Nederlands","Progress":"Completed","ProgressNL":"Afgelopen","PublicFlag":1,"CheckedFlag":0,"ND":"2009-07-03","UD":"2010-06-15","DMPFlag":0,"Budget":73574,"BudgetCurrency":"EUR"},"parent":null,"persons":null,"projects":null,"events":null,"datasets":null,"institutes":[{"instituterec":{"Acronym":"SPHERE","ProPartID":10582,"PublicFlag":1,"OrigNameLangCode":"en","OrigNameLangID":15,"FullOrigName":"University of Antwerp; Faculty of Sciences; Department of Biology; Research group Systemic Physiological and\r\nEcotoxicological Research","Line1":"Campus Middelheim","Line2":"Groenenborgerlaan 171 - Gebouw U","Line3":"2020 Antwerpen","Line4":null,"InsID":108,"FullStandardName":"Universiteit Antwerpen; Faculteit Wetenschappen; Departement Biologie; Onderzoeksgroep Systemisch Fysiologisch en Ecotoxicologisch Onderzoek","Role":null,"RoleID":null,"EncAddress":"Campus Middelheim, Groenenborgerlaan 171 - Gebouw U, 2020 Antwerpen, Belgium"},"parent":null,"institutes":null,"references":null,"conferences":null,"datasets":null,"persons":[{"Surname":"Blust","Firstname":"Ronny","Initials":"R.","LeaderFlag":0,"PersID":201,"Role":"Promotor","RoleID":8,"PastInstitute":1,"BeginDay":null,"BeginMonth":null,"BeginYear":null,"EndDay":null,"EndMonth":null,"EndYear":null},{"Surname":"Weijs","Firstname":"Liesbeth","Initials":"L.","LeaderFlag":0,"PersID":16339,"Role":null,"RoleID":null,"PastInstitute":1,"BeginDay":null,"BeginMonth":null,"BeginYear":null,"EndDay":null,"EndMonth":null,"EndYear":null}],"pastpers":null,"subpers":null,"projects":null,"urls":null,"pictures":null,"published":null,"affrefs":null,"collections":null,"thesterms":null,"taxterms":null,"geoterms":null,"thestermsFRIS":null,"nXtins":null,"previns":null,"spcols":null,"resmessage":"no id specified","complete":0,"participantrec":null,"peerrevs":null,"urlmaps":null},{"instituterec":{"Acronym":"IWT","ProPartID":10583,"PublicFlag":1,"OrigNameLangCode":"en","OrigNameLangID":15,"FullOrigName":"Flemish Government; Economy, Science and Innovation; Intistute for Innovation by Science and Technology","Line1":null,"Line2":null,"Line3":null,"Line4":null,"InsID":2180,"FullStandardName":"Vlaamse overheid; Beleidsdomein Economie, Wetenschap en Innovatie; Agentschap voor Innovatie door Wetenschap en Technologie","Role":"Sponsor","RoleID":3,"EncAddress":""},"parent":null,"institutes":null,"references":null,"conferences":null,"datasets":null,"persons":[],"pastpers":null,"subpers":null,"projects":null,"urls":null,"pictures":null,"published":null,"affrefs":null,"collections":null,"thesterms":null,"taxterms":null,"geoterms":null,"thestermsFRIS":null,"nXtins":null,"previns":null,"spcols":null,"resmessage":"no id specified","complete":0,"participantrec":null,"peerrevs":null,"urlmaps":null}],"refs":null,"urls":null,"thesterms":null,"taxterms":null,"geoterms":null,"funderids":[{"FunderID":"71499","ThestID":181476,"FunderType":"Other contract id"}],"othtermsFRIS":null,"pictures":[],"spcols":null,"resmessage":"","complete":1}