{"projectrec":{"ProID":4089,"StandardTitle":"Exploring the diversity of methane-oxidizing bacteria in marine environments for industrial biotechnologie","OrigTitle":null,"Acronym":null,"AbstractEnglish":"Methane oxidizing bacteria (MOB), or methanotrophs remove 30Tg of methane annually (range 15-45Tg Y-1; ± 6% of global emissions). In addition, these bacteria exhibit a wide range of growing conditions and contain key enzymes with a remarkably broad substrate specificity. Thanks to this versatile character they have a high potential for application in industrial biotechnology, including (i) geoengineering the climate by the fixation of methane from anthropogenic and natural gas to biomass and CO2, (ii) bioremediation of pollutants (eg chlorinated hydrocarbons , aromatic compounds, ... and production of economically relevant metabolites (eg single-cell proteins, ectoine, polyhydroxyalkanoates, .... Nevertheless, there are as yet no applications of MOB widely commercialized, mainly due to the lack of strains with the right properties such as high growth rate and high cell density. Isolation of new strains in this respect is required to expand our knowledge about methanotrophs. So far, most studies focused on terrestrial ecosystems, given the large annual methane emissions, however, marine ecosystems, which annually contribute for 1-20% of the total methane emission were always ignored. As a result little is known about the MOB diversity in these ecosystems. Yet marine systems offer several advantages with regard to biotechnology. Furthermore, knowledge about methanotrophs and their activities is important to understand the microbial mediation of the greenhouse gas methane under climate change and human activities in marine ecosystems.","AbstractOtherLang":"Methaan oxiderende bacteriën (MOB), ook methanotrofen genaamd, verwijderen jaarlijks 30Tg methaan (range 15-45Tg/jaar; ± 6% van de globale uitstoot). Daarnaast vertonen deze bacteriën een brede range aan groeicondities en beschikken ze over sleutelenzymen die een opmerkelijk brede substraatspecificiteit hebben. Dankzij dit veelzijdig karakter hebben ze een hoog potentieel voor toepassing in de industriële biotechnologie, waaronder (i) geoengineering van het klimaat door de fixatie van methaan uit antropogene en natuurlijke gasstromen tot biomassa en CO2, (ii) bioremediatie van verontreinigde stoffen (bv gechloreerde koolwaterstoffen, aromatische verbindingen, … en productie van economisch relevante metabolieten (bv single-cell proteïnen, ectoine, polyhydroxyalkanoaten, … . Desondanks zijn er tot op heden nog geen toepassingen van MOB op grote schaal gecommercialiseerd, wat voornamelijk te wijten is aan het geb rek van stammen met de juiste eigenschappen, zoals hoge groeisnelheid en celdichtheid. Isolatie van nieuwe stammen is in dit opzicht vereist om onze kennis rond methanotrofen uit te breiden. Tot nog toe lag de focus steeds op terrestrische ecosystemen gezien de grote jaarlijkse methaanuitstoot, echter mariene ecosystemen, die jaarlijks voor 1-20% bijdragen aan de totale methaan emissie op wereldvlak, werden steeds genegeerd. Hierdoor is slechts weinig geweten over de MOB diversiteit in deze ecosystemen. Toch beschikken mariene systemen over verschillende voordelen m.b.t. biotechnologie. Verder is kennis rond de verspreiding van methanotrofen en hun activiteiten in mariene omgevingen onmisbaar om inzichten te verwerven naar hun bemiddeling in de huidige klimaatsopwarming problematiek.","DateLastModified":{"date":"2024-05-06 10:25:46.257000","timezone_type":1,"timezone":"+00:00"},"ParentProID":null,"BeginYear":null,"EndYear":null,"BMonth":null,"EMonth":null,"BeginMonth":null,"EndMonth":null,"OrigTitleLangCode":null,"OrigTitleLangID":null,"OrigTitleLangNL":null,"OrigTitleLang":null,"OtherAbstractLangCode":"nl","OtherAbstractLangID":41,"OtherAbstractLang":"Dutch","OtherAbstractLangNL":"Nederlands","Progress":null,"ProgressNL":null,"PublicFlag":1,"CheckedFlag":0,"ND":"2012-08-27","UD":"2012-08-27","DMPFlag":0,"Budget":null,"BudgetCurrency":"EUR"},"parent":null,"persons":null,"projects":null,"events":null,"datasets":null,"institutes":[{"instituterec":{"Acronym":"IWT","ProPartID":13198,"PublicFlag":1,"OrigNameLangCode":"en","OrigNameLangID":15,"FullOrigName":"Flemish Government; Economy, Science and Innovation; Intistute for Innovation by Science and Technology","Line1":null,"Line2":null,"Line3":null,"Line4":null,"InsID":2180,"FullStandardName":"Vlaamse overheid; Beleidsdomein Economie, Wetenschap en Innovatie; Agentschap voor Innovatie door Wetenschap en Technologie","Role":null,"RoleID":null,"EncAddress":""},"parent":null,"institutes":null,"references":null,"conferences":null,"datasets":null,"persons":[],"pastpers":null,"subpers":null,"projects":null,"urls":null,"pictures":null,"published":null,"affrefs":null,"collections":null,"thesterms":null,"taxterms":null,"geoterms":null,"thestermsFRIS":null,"nXtins":null,"previns":null,"spcols":null,"resmessage":"no id specified","complete":0,"participantrec":null,"peerrevs":null,"urlmaps":null},{"instituterec":{"Acronym":null,"ProPartID":13199,"PublicFlag":1,"OrigNameLangCode":"en","OrigNameLangID":15,"FullOrigName":"Ghent University; Faculty of Sciences; Department of Biochemistry and Microbiology","Line1":"K.L. Ledeganckstraat 35","Line2":"9000 Gent","Line3":null,"Line4":null,"InsID":416,"FullStandardName":"Universiteit Gent; Faculteit Wetenschappen; Vakgroep Biochemie en Microbiologie","Role":null,"RoleID":null,"EncAddress":"K.L. 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