Mussels from the River Cecina showed a general alteration of all the biomarkers investigated, accompanied by an elevation of tissue metal levels. However, some differences in specific responses occurred between transplanted and native mussels. Early biomarkers, such as those based on DNA and lysosomal membrane integrity, were induced at similar degree in native and transplanted mussels; while alterations resulting from cumulative events, as the increase of micronuclei frequency were much more elevated in native specimens (23.1 ± 7.6) than in transplanted (9.3 ± 4.7) and reference ones (5.8 ± 5.2). Similarly, the comparison between lipofuscin accumulation and mean lysosomal diameter in impacted and control sites, gave significant differences exclusively with transplanted mussels. These results suggest that the parallel use of caged and native mussels in environmental biomonitoring can improve the characterization of the study area.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Cellular biomarkers for monitoring estuarine environments: transplanted versus native mussels","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-06-10 01:31:31.910798","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"biomarkers; ecotoxicology; DNA damage; lysosomal alterations; mussel;micronucleus test","OtherDescriptors":null,"Notes":null,"AnaPub":2006,"MonPub":null,"DateUpdate":"2020-10-19","DateCreate":"2006-06-22","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000237813400001","VABBcode":null,"OpenAcc":0,"DOI":"10.1016/j.aquatox.2005.12.013"},"refs":null,"anarec":{"AnaID":100039,"PubliDate":2006,"Pagination":"339-347","XtraPublOfAnaID":null,"ISBN":null,"Volume":"77","Issue":"4","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":42203,"SerRR":"Aquatic Toxicology. 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