{"refrec":{"BRefID":111710,"RR":"<b>Noppe, H.; Arijs, K.; De Wasch, K.; Van Cruchten, S.; Poelmans, S.; Courtheyn, D.; Cobbaert, E.; Gillis, W.; Vanthemsche, P.; De Brabander, H.F.; Janssen, C.R.; Van Hoof, N.<\/b> (2006). Biological and chemical approaches for the detection and identification of illegal estrogens in water based solutions, <b><i>in<\/i><\/b>: Noppe, H. <i>Analytiek van hormoon verstorende stoffen in milieumatrices = Analytics of endocrine disrupting chemicals in environmental matrices.<\/i> pp. 59-72","BEntID":306960,"PublicFlag":1,"CheckedFlag":0,"wosflag":0,"vabbflag":0,"RefStringPartII":", <b><i>in<\/i><\/b>: Noppe, H. <i>Analytiek van hormoon verstorende stoffen in milieumatrices = Analytics of endocrine disrupting chemicals in environmental matrices.<\/i> pp. 59-72","DocTypID":17,"DocType":"Book chapters","MarineFlag":0,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Noppe, H.; Arijs, K.; De Wasch, K.; Van Cruchten, S.; Poelmans, S.; Courtheyn, D.; Cobbaert, E.; Gillis, W.; Vanthemsche, P.; De Brabander, H.F.; Janssen, C.R.; Van Hoof, N.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Noppe, H. <i>et al.<\/i>","Englishabstract":"Continuous production of new products used as growth promotors in animal husbandry, sports doping and products for body-building, requires residue laboratories to initiate research on developing a strategy for the identification of \u2018unknown\u2019 components. In this study, a strategy for elucidating the identity, the structure and the possible effects of illegal estrogenic compounds in an unidentified water based solution is presented. To obtain complete information on the composition and activity of the unidentified product a multi-disciplinary approach was needed. A case-study is described with a \u2018solution X\u2019 found during a raid. At first, in vivo techniques (animal trials with mice, anatomical and histological research) were combined with in vitro techniques (the yeast estrogenic screen (YES)). In a later state of the investigation, HPLC fractionation, liquid chromatography-multiple mass spectrometry (LCMS- MS) and gas chromatography-multiple mass spectrometry (GC-MS-MS) were used. Finally, the identity of \u2018solution X\u2019 was confirmed in a low concentration range (10 ng.l-1 E1 and 400 ng.l-1 EE2).","AbstractOtherLang":null,"BibLvlCode":"AM","StandardTitle":"Biological and chemical approaches for the detection and identification of illegal estrogens in water based solutions","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2024-12-10 01:33:17.368041","timezone_type":1,"timezone":"+01:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"animal trials; anatomy; GC-MSn; histology; LC-MSn; YES","OtherDescriptors":null,"Notes":null,"AnaPub":2006,"MonPub":null,"DateUpdate":"2019-08-28","DateCreate":"2007-07-20","SecASFANote":null,"ConfID":null,"PeerRev":0,"VlizCoreFlag":1,"WoScode":null,"VABBcode":null,"OpenAcc":0},"refs":null,"anarec":{"AnaID":111710,"PubliDate":2006,"Pagination":"59-72","XtraPublOfAnaID":null,"ISBN":"978-90-5864-100-7","Volume":null,"Issue":null,"BRefMon":102585,"BRefMonRR":"<b>Noppe, H.<\/b> (2006). Analytiek van hormoon verstorende stoffen in milieumatrices = Analytics of endocrine disrupting chemicals in environmental matrices. PhD Thesis. Universiteit Gent. Faculteit Diergeneeskunde: Gent. ISBN 978-90-5864-100-7. 153 pp.","BRefXtra":null,"BRefXtraRR":null,"SerBRefID":null,"SerRR":null,"StandardTitleSer":null,"ISSN":null,"AbbrevSer":null,"StandardTitleMon":"Analytiek van hormoon verstorende stoffen in milieumatrices = Analytics of endocrine disrupting chemicals in environmental matrices","StartPage":59,"Pages":14,"ToPubliDate":null,"BRefBibLvlCode":"M","SerNotes":null,"AutString":"Noppe, H."},"monrec":null,"serrec":null,"relations":null,"relationsRev":[{"XBRefID":111712,"RefStrFull":"<b>Noppe, H.; Arijs, K.; De Wasch, K.; Van Cruchten, S.; Poelmans, S.; Courtheyn, D.; Cobbaert, E.; Gillis, W.; Vanthemsche, P.; De Brabander, H.F.; Janssen, C.R.; Van Hoof, N.<\/b> (2006). Biological and chemical approaches for the detection and identification of illegal estrogens in water based solutions. <i>Vet. Res. Comm. 30(6)<\/i>: 577-585. <a href=\"https:\/\/dx.doi.org\/10.1007\/s11259-006-3326-0\" target=\"_blank\">https:\/\/dx.doi.org\/10.1007\/s11259-006-3326-0<\/a>","RelID":4,"RelationY":"Related to","StandardTitle":"Biological and chemical approaches for the detection and identification of illegal estrogens in water based solutions"}],"addrec":null,"othpubs":null,"ownerships":null,"authors":[{"AutName":"Noppe","Firstname":"Herlinde","Initials":"H.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":306960,"AutID":35305,"OrderNr":1,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":5299,"InsID":null},{"AutName":"Arijs","Firstname":"Katrien","Initials":"K.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":306960,"AutID":44745,"OrderNr":2,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":2817,"InsID":null},{"AutName":"De Wasch","Firstname":"Katia","Initials":"K.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":306960,"AutID":26158,"OrderNr":3,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":5594,"InsID":null},{"AutName":"Van Cruchten","Firstname":null,"Initials":"S.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":306960,"AutID":74397,"OrderNr":4,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Poelmans","Firstname":"Sofie","Initials":"S.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":306960,"AutID":26159,"OrderNr":5,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":10753,"InsID":null},{"AutName":"Courtheyn","Firstname":"Dirk","Initials":"D.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":306960,"AutID":43370,"OrderNr":6,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Cobbaert","Firstname":null,"Initials":"E.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":306960,"AutID":74398,"OrderNr":7,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Gillis","Firstname":null,"Initials":"W.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":306960,"AutID":74399,"OrderNr":8,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Vanthemsche","Firstname":null,"Initials":"P.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":306960,"AutID":74400,"OrderNr":9,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"De Brabander","Firstname":null,"Initials":"H.F.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":306960,"AutID":44762,"OrderNr":10,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":4454,"InsID":null},{"AutName":"Janssen","Firstname":"Colin","Initials":"C.R.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":306960,"AutID":11628,"OrderNr":11,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":"0000-0002-7781-6679","PersID":50,"InsID":null},{"AutName":"Van Hoof","Firstname":"Nathalie","Initials":"N.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":306960,"AutID":43371,"OrderNr":12,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null}],"mapdetails":null,"datasets":null,"monographs":null,"monparts":null,"serparts":null,"BEntOpen":null,"BEntPrivate":null,"availability":[{"BInstID":122325,"LibID":36,"BRefID":111710,"EmbargoDate":null,"FullEmbargoDate":null,"PhysMedID":16,"hasOCRd":1,"ShelfLocCode":"122325","RFID":null,"PaidValue":null,"Medium":"Server","Description":null,"Acronym":"VLIZ","Library":"Vlaams Instituut voor de Zee","DutchTerm":"Open Marien Archief","URL":null,"ClassifID":235,"Classification":"Open Marine Archive","ReqLink":null,"ClassifTypID":5,"URLLocation":"https:\/\/www.vliz.be\/imisdocs\/publications\/","SubDir":0,"InternalReq":0,"LoggedInReq":0,"Disclaimer":"Disclaimer_OMA","DutchDisclaimer":null,"FileFormat":".pdf","FileDescr":"pdf","InsPub":1,"InsID":36,"FileFormID":6,"LendableFlag":1,"PublicFlag":1,"orderLib":"A","Notes":null,"AccConID":null,"AccessConstraint":null,"LicURL":null}],"litstyles":null,"thespers":null,"arch2discl":null,"SERpubls":null,"MONpubls":[{"PublName":"Universiteit Gent. Faculteit Diergeneeskunde","Place":"Gent"}],"pictures":[],"thestermsPath":[{"ThesaurusTerm":"Detection","ThestID":2265,"Acronym":"ASFA","ThesTermPath":"Detection"},{"ThesaurusTerm":"Estrogens","ThestID":2894,"Acronym":"ASFA","ThesTermPath":"Estrogens"},{"ThesaurusTerm":"Identification","ThestID":4228,"Acronym":"ASFA","ThesTermPath":"Identification"}],"thestermsASFA":[{"ThesaurusTerm":"Detection"},{"ThesaurusTerm":"Identification"}],"taxtermsASFA":null,"geotermsASFA":null,"collections":[{"Collection":"OMA - Open Marien Archief","ShortName":"OMA"},{"Collection":"Section Ecotox","ShortName":"Ecotox"}],"conf":null,"proj":[{"ProID":1068,"Acronym":"ENDIS-RISKS","ProStandardTitle":"Endocrine disruption in the Scheldt Estuary: distribution, exposure and effects","BYear":2002,"BMonth":2,"EYear":2006,"EMonth":4,"FP7Code":null,"RelID":null,"Relation":null,"DutchTerm":null}],"Physdatasets":null,"spcols":{"222":{"SpName":"BMB - Belgische Mariene Bibliografie","SpColID":222,"ParSpColID":null,"TopParID":null,"ShortName":"BMB","URLLocation":null,"LibID":36,"OpenRepoFlag":null,"SpTypID":null,"TopParIDNotWebsite":null,"SpColPath":"BMB"},"221":{"SpName":"OMA - Open Marien Archief","SpColID":221,"ParSpColID":null,"TopParID":null,"ShortName":"OMA","URLLocation":null,"LibID":36,"OpenRepoFlag":1,"SpTypID":null,"TopParIDNotWebsite":null,"SpColPath":"OMA"},"476":{"SpName":"Section Ecotox","SpColID":476,"ParSpColID":null,"TopParID":null,"ShortName":"Ecotox","URLLocation":null,"LibID":null,"OpenRepoFlag":null,"SpTypID":null,"TopParIDNotWebsite":null,"SpColPath":"Ecotox"}},"doi":null,"publs":null,"serparttypes":null,"monauthors":[{"AutName":"Noppe","Initials":"H.","CorporateFlag":0,"BEntID":99420,"AutID":35305,"OrderNr":1,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"AutStrTrunc":"Noppe, H."}],"MParts":null,"SParts":null,"hLibs":null,"langs":[{"BEntID":306960,"AbstractFlag":-1,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"},{"BEntID":306960,"AbstractFlag":0,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"}],"urls":null,"thesterms":[{"ThesaurusTerm":"Detection","ThestID":2265,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Estrogens","ThestID":2894,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Identification","ThestID":4228,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"}],"taxterms":null,"geoterms":null,"othterms":null,"asfacodes":null,"asfa2codes":null,"thestermsFRIS":[{"ThesaurusTerm":"Detection","DutchTerm":"Detectie","ThestID":2265,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Estrogens","DutchTerm":"Oestrogenen","ThestID":2894,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Identification","DutchTerm":"Identificatie","ThestID":4228,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"}],"taxtermsFRIS":null,"geotermsFRIS":null,"othtermsFRIS":null,"resmessage":"","complete":1,"sessions":{"newSesName":"Haspeslagh, Jan, J.","newSesDate":{"date":"2007-07-20 10:08:43.347000","timezone_type":3,"timezone":"Europe\/Brussels"},"updSesName":"Bouchti, Zohra, Z.","updSesDate":{"date":"2019-08-28 08:11:57.943000","timezone_type":3,"timezone":"Europe\/Brussels"}}}