{"refrec":{"BRefID":112780,"RR":"<b>Rank, J.; Lehtonen, K.K.; Strand, J.; Laursen, M.</b> (2007). DNA damage, acetylcholinesterase activity and lysosomal stability in native and transplanted mussels (<i>Mytilus edulis</i>) in areas close to coastal chemical dumping sites in Denmark. <i>Aquat. Toxicol. 84(1)</i>: 50-61. <a href=\"https://dx.doi.org/10.1016/j.aquatox.2007.05.013\" target=\"_blank\">https://dx.doi.org/10.1016/j.aquatox.2007.05.013</a>","BEntID":107346,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":0,"RefStringPartII":". <i>Aquat. Toxicol. 84(1)</i>: 50-61. <a href=\"https://dx.doi.org/10.1016/j.aquatox.2007.05.013\" target=\"_blank\">https://dx.doi.org/10.1016/j.aquatox.2007.05.013</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Rank, J.; Lehtonen, K.K.; Strand, J.; Laursen, M.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Rank, J. <i>et al.</i>","Englishabstract":"Biomarkers of genotoxicity (DNA damage, measured as tail moment in the Comet assay), neurotoxicity (acetylcholinesterase inhibition, AChE) and general stress (lysosomal membrane stability, LMS) were studied in native and transplanted blue mussels (<i>Mytilus edulis</i>) in coastal areas of western Denmark potentially affected by anthropogenic pollution originating from chemical dumping sites. The results indicate responses to pollution in all the biomarkers applied at the suspected areas, but the results were not consistent. Seasonal fluctuations in exposure situations at the study sites make interpretation of chemical pollution complex, as seen especially in the variability in results on DNA damage, and also in regard to AChE activity. These investigations further stress the importance of understanding the effects of natural factors (salinity, temperature, water levels, rain and storm events) in correct interpretation of the biomarker data obtained. In addition, adaptation of populations to local contamination may play a role in some of the response patterns observed. ","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"DNA damage, acetylcholinesterase activity and lysosomal stability in native and transplanted mussels (<i>Mytilus edulis</i>) in areas close to coastal chemical dumping sites in Denmark","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-05-23 01:31:17.100575","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"DNA damage; comet assay; acetylcholinesterase activity; lysosomalmembrane stability; biomarker; pollution monitoring; blue mussel;Mytilus edulis","OtherDescriptors":null,"Notes":null,"AnaPub":2007,"MonPub":null,"DateUpdate":"2020-10-22","DateCreate":"2007-08-20","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000249165800006","VABBcode":null,"OpenAcc":0,"DOI":"10.1016/j.aquatox.2007.05.013"},"refs":null,"anarec":{"AnaID":112780,"PubliDate":2007,"Pagination":"50-61","XtraPublOfAnaID":null,"ISBN":null,"Volume":"84","Issue":"1","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":42203,"SerRR":"Aquatic Toxicology. Elsevier Science: Tokyo; New York; London; Amsterdam.  ISSN 0166-445X; e-ISSN 1879-1514","StandardTitleSer":"Aquatic Toxicology","ISSN":"0166-445X","AbbrevSer":"Aquat. Toxicol.","StandardTitleMon":null,"StartPage":50,"Pages":12,"ToPubliDate":null,"BRefBibLvlCode":"S","SerNotes":null},"monrec":null,"serrec":null,"relations":null,"relationsRev":null,"addrec":null,"othpubs":null,"ownerships":null,"authors":[{"AutName":"Rank","Firstname":"Jette","Initials":"J.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":107346,"AutID":75146,"OrderNr":1,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Lehtonen","Firstname":"Kari","Initials":"K.K.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":107346,"AutID":39467,"OrderNr":2,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Strand","Firstname":"Jakob","Initials":"J.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":107346,"AutID":75147,"OrderNr":3,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Laursen","Firstname":"Martha","Initials":"M.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":107346,"AutID":75148,"OrderNr":4,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null}],"mapdetails":null,"datasets":null,"monographs":null,"monparts":null,"serparts":null,"BEntOpen":null,"BEntPrivate":null,"availability":[{"BInstID":353251,"LibID":36,"BRefID":112780,"EmbargoDate":null,"FullEmbargoDate":null,"PhysMedID":16,"hasOCRd":null,"ShelfLocCode":"353251","RFID":null,"PaidValue":null,"Medium":"Server","Description":"Interne VLIZ documenten","Acronym":"VLIZ","Library":"Vlaams Instituut voor de Zee","DutchTerm":"Non-open access","URL":null,"ClassifID":228,"Classification":"Non-open access","ReqLink":1,"ClassifTypID":3,"URLLocation":"https://www.vliz.be/imisdocs/publications/","SubDir":1,"InternalReq":1,"LoggedInReq":1,"Disclaimer":"Disclaimer_VLIZ_Intern","DutchDisclaimer":"<p>Deze publicatie is enkel beschikbaar voor persoonlijk gebruik binnen de Innovocean site <br />en mag op geen enkele manier verder worden verspreid.</p>","FileFormat":".pdf","FileDescr":"pdf","InsPub":1,"InsID":36,"FileFormID":6,"LendableFlag":1,"PublicFlag":1,"orderLib":"A","Notes":null,"AccConID":null,"AccessConstraint":null,"LicURL":null}],"litstyles":null,"thespers":null,"arch2discl":null,"SERpubls":[{"PublName":"Elsevier Science","City":"Tokyo; New York; London; Amsterdam"}],"MONpubls":null,"pictures":[],"thestermsPath":[{"ThesaurusTerm":"Biomarkers","ThestID":9475,"Acronym":"ASFA","ThesTermPath":"Biomarkers"},{"ThesaurusTerm":"Denmark","ThestID":183637,"Acronym":"ASFA_GEOT","ThesTermPath":"Denmark"},{"ThesaurusTerm":"Pollution monitoring","ThestID":6397,"Acronym":"ASFA","ThesTermPath":"Monitoring > Environmental monitoring > Pollution monitoring"}],"thestermsASFA":[{"ThesaurusTerm":"Biomarkers"},{"ThesaurusTerm":"Denmark"},{"ThesaurusTerm":"Pollution monitoring"}],"taxtermsASFA":[{"TaxTerm":"Mytilus edulis"}],"geotermsASFA":[{"GeoTerm":"Denmark"}],"collections":null,"conf":null,"proj":null,"Physdatasets":null,"spcols":null,"doi":null,"publs":null,"serparttypes":null,"monauthors":null,"MParts":null,"SParts":null,"hLibs":null,"langs":[{"BEntID":107346,"AbstractFlag":-1,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"},{"BEntID":107346,"AbstractFlag":0,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"}],"urls":[{"URL":"https://dx.doi.org/10.1016/j.aquatox.2007.05.013","externalID":"10.1016/j.aquatox.2007.05.013","URLTypeCode":"DOI","URLID":8198,"URLTypID":13,"URLType":"DOI","URLPrefix":"http://dx.doi.org/"}],"thesterms":[{"ThesaurusTerm":"Biomarkers","ThestID":9475,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Denmark","ThestID":183637,"Acronym":"ASFA_GEOT","ThesTypID":34,"ThesType":"ASFA Geoterms"},{"ThesaurusTerm":"Pollution monitoring","ThestID":6397,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"}],"taxterms":[{"TaxTerm":"Mytilus edulis","AphiaID":140480,"TaxtID":25121}],"geoterms":[{"GeoTerm":"Denmark","GeoObjectID":2157,"GeotID":209}],"othterms":[{"OtherTerm":"Acetylcholinesterase activity","OthtID":2035},{"OtherTerm":"Blue mussel","OthtID":16809},{"OtherTerm":"Comet assay","OthtID":2602},{"OtherTerm":"Dna damage","OthtID":7878},{"OtherTerm":"Lysosomal membrane stability","OthtID":8384}],"asfacodes":null,"asfa2codes":null,"thestermsFRIS":[{"ThesaurusTerm":"Biomarkers","DutchTerm":"Biomarkers","ThestID":9475,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Denmark","DutchTerm":null,"ThestID":183637,"Acronym":"ASFA_GEOT","ThesTypID":34,"ThesType":"ASFA Geoterms"},{"ThesaurusTerm":"Pollution monitoring","DutchTerm":"Pollutiemonitoring","ThestID":6397,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"}],"taxtermsFRIS":[{"TaxTerm":"Mytilus edulis","DutchTerm":"Mossel","AphiaID":140480,"TaxtID":25121}],"geotermsFRIS":[{"GeoTerm":"Denmark","DutchTerm":null}],"othtermsFRIS":[{"OtherTerm":"Acetylcholinesterase activity","DutchTerm":null,"OthtID":2035},{"OtherTerm":"Blue mussel","DutchTerm":null,"OthtID":16809},{"OtherTerm":"Comet assay","DutchTerm":null,"OthtID":2602},{"OtherTerm":"Dna damage","DutchTerm":null,"OthtID":7878},{"OtherTerm":"Lysosomal membrane stability","DutchTerm":null,"OthtID":8384}],"resmessage":"","complete":1,"sessions":{"newSesName":"Chisala, Chilekwa, C.","newSesDate":{"date":"2007-08-20 14:13:55.883000","timezone_type":3,"timezone":"Europe/Brussels"},"updSesName":"Bouchti, Zohra, Z.","updSesDate":{"date":"2020-10-22 06:53:58.010000","timezone_type":3,"timezone":"Europe/Brussels"}}}