{"refrec":{"BRefID":113279,"RR":"<b>Wattanadilok, R.; Sawangwong, P.; Rodrigues, C.; Cidade, H.; Pinto, M.; Pinto, E.; Silva, A.; Kijjoa, A.</b> (2007). Antifungal activity evaluation of the constituents of <i>Haliclona baeri</i> and <i>Haliclona cymaeformis</i>, collected from the Gulf of Thailand. <i>Mar. Drugs 5(2)</i>: 40-51. <a href=\"https://dx.doi.org/10.3390/md502040\" target=\"_blank\">https://dx.doi.org/10.3390/md502040</a>","BEntID":107731,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":0,"RefStringPartII":". <i>Mar. Drugs 5(2)</i>: 40-51. <a href=\"https://dx.doi.org/10.3390/md502040\" target=\"_blank\">https://dx.doi.org/10.3390/md502040</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Wattanadilok, R.; Sawangwong, P.; Rodrigues, C.; Cidade, H.; Pinto, M.; Pinto, E.; Silva, A.; Kijjoa, A.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Wattanadilok, R. <i>et al.</i>","Englishabstract":"A new compound maleimide-5-oxime was isolated, together with 3,4-dihydroxybenzoic acid, tetillapyrone, from the ethyl acetate extract of the marine sponge <i>Haliclona baeri </i>while tetillapyrone, nortetillapyrone, p-hydroxybenzaldehyde and phenylacetic acid were isolated from the ethyl acetate extract of <i>Haliclona cymaeformis</i>, collected from the Gulf of Thailand. The structures of tetillapyrone and nortetillapyrone were re-examined using HMBC correlations. Maleimide-5-oxime, tetillapyrone and nortetillapyrone were found to be inactive against three human tumor cell lines (the estrogen-dependent ER(+) MCF-7, the estrogen-independent ER(-) MDA-MB-231 and NCI-H460. Maleimide-5-oxime, p-hydroxybenzaldehyde, phenylacetic acid, tetillapyrone and nortetillapyrone were evaluated for their growth inhibitory effect against seven yeasts and eight filamentous fungi. Only nortetillapyrone showed antifungal activity, with a preponderance on the dermatophytic filamentous fungi. ","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Antifungal activity evaluation of the constituents of <i>Haliclona baeri</i> and <i>Haliclona cymaeformis</i>, collected from the Gulf of Thailand","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-06-02 01:31:12.783873","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":null,"Notes":null,"AnaPub":2007,"MonPub":null,"DateUpdate":"2020-10-22","DateCreate":"2007-08-27","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000247557300004","VABBcode":null,"OpenAcc":1,"DOI":"10.3390/md502040"},"refs":null,"anarec":{"AnaID":113279,"PubliDate":2007,"Pagination":"40-51","XtraPublOfAnaID":null,"ISBN":null,"Volume":"5","Issue":"2","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":113252,"SerRR":"Marine Drugs. Molecular Diversity Preservation International (MDPI): Basel.  ISSN 1660-3397; e-ISSN 1660-3397","StandardTitleSer":"Marine Drugs","ISSN":"1660-3397","AbbrevSer":"Mar. Drugs","StandardTitleMon":null,"StartPage":40,"Pages":12,"ToPubliDate":null,"BRefBibLvlCode":"S","SerNotes":null},"monrec":null,"serrec":null,"relations":null,"relationsRev":null,"addrec":null,"othpubs":null,"ownerships":null,"authors":[{"AutName":"Wattanadilok","Firstname":null,"Initials":"R.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":107731,"AutID":75428,"OrderNr":1,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Sawangwong","Firstname":null,"Initials":"P.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":107731,"AutID":75442,"OrderNr":2,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Rodrigues","Firstname":null,"Initials":"C.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":107731,"AutID":75443,"OrderNr":3,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Cidade","Firstname":null,"Initials":"H.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":107731,"AutID":75444,"OrderNr":4,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Pinto","Firstname":null,"Initials":"M.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":107731,"AutID":75431,"OrderNr":5,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Pinto","Firstname":null,"Initials":"E.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":107731,"AutID":75445,"OrderNr":6,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Silva","Firstname":null,"Initials":"A.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":107731,"AutID":75446,"OrderNr":7,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Kijjoa","Firstname":"Anake","Initials":"A.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":107731,"AutID":75427,"OrderNr":8,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null}],"mapdetails":null,"datasets":null,"monographs":null,"monparts":null,"serparts":null,"BEntOpen":null,"BEntPrivate":null,"availability":[{"BInstID":353290,"LibID":36,"BRefID":113279,"EmbargoDate":null,"FullEmbargoDate":null,"PhysMedID":16,"hasOCRd":1,"ShelfLocCode":"353290","RFID":null,"PaidValue":null,"Medium":"Server","Description":"VLIZ Open Access","Acronym":"VLIZ","Library":"Vlaams Instituut voor de Zee","DutchTerm":"Open access","URL":null,"ClassifID":53,"Classification":"Open access","ReqLink":null,"ClassifTypID":1,"URLLocation":"https://www.vliz.be/imisdocs/publications/","SubDir":null,"InternalReq":0,"LoggedInReq":0,"Disclaimer":null,"DutchDisclaimer":null,"FileFormat":".pdf","FileDescr":"pdf","InsPub":1,"InsID":36,"FileFormID":6,"LendableFlag":1,"PublicFlag":1,"orderLib":"A","Notes":null,"AccConID":null,"AccessConstraint":null,"LicURL":null}],"litstyles":null,"thespers":null,"arch2discl":null,"SERpubls":[{"PublName":"Molecular Diversity Preservation International (MDPI)","City":"Basel"}],"MONpubls":null,"pictures":[],"thestermsPath":[{"ThesaurusTerm":"Antifungals","ThestID":455,"Acronym":"ASFA","ThesTermPath":"Antifungals"},{"ThesaurusTerm":"Dermatophytes","ThestID":114889,"Acronym":"CAB","ThesTermPath":"Pathogens > Dermatophytes"}],"thestermsASFA":[{"ThesaurusTerm":"Dermatophytes"}],"taxtermsASFA":[{"TaxTerm":"Haliclona baeri"},{"TaxTerm":"Haliclona cymaeformis"}],"geotermsASFA":null,"collections":null,"conf":null,"proj":null,"Physdatasets":null,"spcols":null,"doi":null,"publs":null,"serparttypes":null,"monauthors":null,"MParts":null,"SParts":null,"hLibs":null,"langs":[{"BEntID":107731,"AbstractFlag":0,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"},{"BEntID":107731,"AbstractFlag":1,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"}],"urls":[{"URL":"https://dx.doi.org/10.3390/md502040","externalID":"10.3390/md502040","URLTypeCode":"DOI","URLID":87104,"URLTypID":13,"URLType":"DOI","URLPrefix":"http://dx.doi.org/"}],"thesterms":[{"ThesaurusTerm":"Antifungals","ThestID":455,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Dermatophytes","ThestID":114889,"Acronym":"CAB","ThesTypID":4,"ThesType":"CAB Thesaurus"}],"taxterms":[{"TaxTerm":"Haliclona baeri","AphiaID":166321,"TaxtID":36491},{"TaxTerm":"Haliclona cymaeformis","AphiaID":166343,"TaxtID":36492}],"geoterms":null,"othterms":[{"OtherTerm":"Antifungal activity","OthtID":16879},{"OtherTerm":"Nortetillapyrone","OthtID":16881},{"OtherTerm":"Tetillapyrone","OthtID":16882}],"asfacodes":null,"asfa2codes":null,"thestermsFRIS":[{"ThesaurusTerm":"Antifungals","DutchTerm":null,"ThestID":455,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Dermatophytes","DutchTerm":null,"ThestID":114889,"Acronym":"CAB","ThesTypID":4,"ThesType":"CAB Thesaurus"}],"taxtermsFRIS":[{"TaxTerm":"Haliclona baeri","DutchTerm":null,"AphiaID":166321,"TaxtID":36491},{"TaxTerm":"Haliclona cymaeformis","DutchTerm":null,"AphiaID":166343,"TaxtID":36492}],"geotermsFRIS":null,"othtermsFRIS":[{"OtherTerm":"Antifungal activity","DutchTerm":null,"OthtID":16879},{"OtherTerm":"Nortetillapyrone","DutchTerm":null,"OthtID":16881},{"OtherTerm":"Tetillapyrone","DutchTerm":null,"OthtID":16882}],"resmessage":"","complete":1,"sessions":{"newSesName":"Haspeslagh, Jan, J.","newSesDate":{"date":"2007-08-27 09:15:01.593000","timezone_type":3,"timezone":"Europe/Brussels"},"updSesName":"Bouchti, Zohra, Z.","updSesDate":{"date":"2020-10-22 06:53:58.010000","timezone_type":3,"timezone":"Europe/Brussels"}}}