{"refrec":{"BRefID":117616,"RR":"<b>Luter, H.M.; Duckworth, A.R.; Syms, C.</b> (2007). Cytotoxic and anti-microbial activity of the sponge <i>Iotrochota</i> sp. as a function of size and spatial competitors. <i>Mar. Biol. Res. 3(5)</i>: 312-318. <a href=\"https://dx.doi.org/10.1080/17451000701635102\" target=\"_blank\">https://dx.doi.org/10.1080/17451000701635102</a>","BEntID":111933,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":null,"RefStringPartII":". <i>Mar. Biol. Res. 3(5)</i>: 312-318. <a href=\"https://dx.doi.org/10.1080/17451000701635102\" target=\"_blank\">https://dx.doi.org/10.1080/17451000701635102</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Luter, H.M.; Duckworth, A.R.; Syms, C.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Luter, H.M.; Duckworth, A.R.; Syms, C.","Englishabstract":"Secondary metabolites from marine invertebrates, such as sponges, have diverse ecological roles and may be used in anti-predation, anti-fouling and spatial competition. The thin encrusting sponge <i>Iotrochota</i> sp., found on the Great Barrier Reef, Australia, contains several novel indoles that may aid in spatial competition. To examine whether levels of surrounding competition affect the toxicity of <i>Iotrochota</i> sp., 24 sponges from Salamander Reef, Central Great Barrier Reef, subject to either high or low levels of surrounding competition, were sampled. Tissue samples were taken from areas where the sponge was in direct competition with neighbouring sessile invertebrates, as well as from areas where competition was less obvious. Compounds from the tissue samples were extracted and tested in both cytotoxicity and anti-microbial assays. However, neither cytotoxicity nor anti-microbial activity varied significantly between the high and low competition treatments. Cytotoxicity was greatest among large sponges, suggesting that size is an important factor contributing to the toxicity of <i>Iotrochota</i> sp. sponges in this study.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Cytotoxic and anti-microbial activity of the sponge <i>Iotrochota</i> sp. as a function of size and spatial competitors","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-06-02 01:31:13.518308","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":null,"Notes":null,"AnaPub":2007,"MonPub":null,"DateUpdate":"2007-12-06","DateCreate":"2007-12-06","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000251511700004","VABBcode":null,"OpenAcc":0,"DOI":"10.1080/17451000701635102"},"refs":null,"anarec":{"AnaID":117616,"PubliDate":2007,"Pagination":"312-318","XtraPublOfAnaID":null,"ISBN":null,"Volume":"3","Issue":"5","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":72882,"SerRR":"Marine Biology Research. 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