{"refrec":{"BRefID":127924,"RR":"<b>Schnitzler, J.G.; Koutrakis, E.T.; Siebert, U.; Thomé, J.-P.; Das, K.</b> (2008). Effects of persistent organic pollutants on the thyroid function of the European sea bass (<i>Dicentrarchus labrax</i>) from the Aegean sea, is it an endocrine disruption? <i>Mar. Pollut. Bull. 56(10)</i>: 1755-1764. <a href=\"http://dx.doi.org/10.1016/j.marpolbul.2008.06.011\" target=\"_blank\">dx.doi.org/10.1016/j.marpolbul.2008.06.011</a>","BEntID":122013,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":1,"RefStringPartII":" <i>Mar. Pollut. Bull. 56(10)</i>: 1755-1764. <a href=\"https://dx.doi.org/10.1016/j.marpolbul.2008.06.011\" target=\"_blank\">https://dx.doi.org/10.1016/j.marpolbul.2008.06.011</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Schnitzler, J.G.; Koutrakis, E.T.; Siebert, U.; Thomé, J.-P.; Das, K.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Schnitzler, J.G. <i>et al.</i>","Englishabstract":"We evaluated the alterations of organochlorinated compounds such as polychlorobiphenyls (PCB), dichloro-diphenyl-dichloroethylene (DDE) and dichloro-diphenyl-trichloroethane (DDT) on the thyroid in wild and cultured sea bass (<i>Dicentrarchus labrax</i>) at environmental concentrations. These compounds influence the endocrine system of many fish species and are qualified as endocrine disruptors. The thyroid seems to be a target organ. Two alteration endpoints: the thyroid histology and the muscular thyroid hormone concentrations, were used simultaneously. High concentrations in PCBs and DDT were detected in muscles, supporting the idea that the Mediterranean fauna could be more polluted than the Atlantic fauna. The high abundance of DDE indicates a progressive degradation of remnant DDT load and the absence of new inputs in this area. Aquaculture sea bass shows a significant higher amount of pollutants on fresh weight basis (especially PCBs) in their muscles compared to the wild sea bass. Those differences may be related mainly to the contaminations of diet. Thyroid parameters vary between wild and aquaculture sea bass, wild sea bass were characterized by higher follicle diameters, epithelial cell heights and muscular T<sub>4</sub> concentrations. A significant relationship between persistent organic pollutants (muscular PCBs and DDT concentration) and the different thyroid parameters (diameters of follicles, epithelial cell heights and muscular T<sub>4</sub> levels) could be observed, which support the hypothesis that these compounds have an adverse impact on thyroid morphometry and function. ","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Effects of persistent organic pollutants on the thyroid function of the European sea bass (<i>Dicentrarchus labrax</i>) from the Aegean sea, is it an endocrine disruption?","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2025-07-02 08:33:14.980000","timezone_type":1,"timezone":"+00:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":null,"Notes":null,"AnaPub":2008,"MonPub":null,"DateUpdate":"2018-05-17","DateCreate":"2008-12-04","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000260745300019","VABBcode":null,"OpenAcc":0,"DOI":"10.1016/j.marpolbul.2008.06.011"},"refs":null,"anarec":{"AnaID":127924,"PubliDate":2008,"Pagination":"1755-1764","XtraPublOfAnaID":null,"ISBN":null,"Volume":"56","Issue":"10","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":43520,"SerRR":"Marine Pollution Bulletin. Macmillan: London.  ISSN 0025-326X; e-ISSN 1879-3363","StandardTitleSer":"Marine Pollution Bulletin","ISSN":"0025-326X","AbbrevSer":"Mar. Pollut. Bull.","StandardTitleMon":null,"StartPage":1755,"Pages":10,"ToPubliDate":null,"BRefBibLvlCode":"S","SerNotes":null},"monrec":null,"serrec":null,"relations":null,"relationsRev":null,"addrec":null,"othpubs":null,"ownerships":null,"authors":[{"AutName":"Schnitzler","Firstname":"Joseph","Initials":"J.G.","Affiliation":"Mare Centre, Laboratory for Oceanology B6c, Liège University","Discriminator":null,"CorporateFlag":0,"BEntID":122013,"AutID":145839,"OrderNr":1,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":"Université de Liège; Faculté des Sciences; Département de Biologie, Ecologie et Evolution; Laboratoire d'Océanologie Biologique","ORCID":null,"PersID":27346,"InsID":459},{"AutName":"Koutrakis","Firstname":"Emmanouil","Initials":"E.T.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":122013,"AutID":21711,"OrderNr":2,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":4307,"InsID":null},{"AutName":"Siebert","Firstname":"Ursula","Initials":"U.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":122013,"AutID":11049,"OrderNr":3,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Thomé","Firstname":"Jean-Pierre","Initials":"J.-P.","Affiliation":"Laboratory of Animal Ecology and Ecotoxicology B6c, Liège University","Discriminator":null,"CorporateFlag":0,"BEntID":122013,"AutID":145841,"OrderNr":4,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":"LEAE","InsFSN":"Université de Liège; Faculté des Sciences; Département de Biologie, Ecologie et Evolution; Laboratoire d'Écologie Animale et Écotoxicologie","ORCID":"0000-0002-0331-7500","PersID":3195,"InsID":479},{"AutName":"Das","Firstname":"Krishna","Initials":"K.","Affiliation":"Mare Centre, Laboratory for Oceanology B6c, Liège University","Discriminator":null,"CorporateFlag":0,"BEntID":122013,"AutID":133407,"OrderNr":5,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":"Université de Liège; Faculté des Sciences; Département de Biologie, Ecologie et Evolution; Laboratoire d'Océanologie Biologique","ORCID":"0000-0003-2689-3348","PersID":3862,"InsID":459}],"mapdetails":null,"datasets":null,"monographs":null,"monparts":null,"serparts":null,"BEntOpen":null,"BEntPrivate":null,"availability":[{"BInstID":141564,"LibID":36,"BRefID":127924,"EmbargoDate":null,"FullEmbargoDate":null,"PhysMedID":16,"hasOCRd":1,"ShelfLocCode":"141564","RFID":null,"PaidValue":null,"Medium":"Server","Description":null,"Acronym":"VLIZ","Library":"Vlaams Instituut voor de Zee","DutchTerm":"Open Marien Archief","URL":null,"ClassifID":235,"Classification":"Open Marine Archive","ReqLink":null,"ClassifTypID":5,"URLLocation":"https://www.vliz.be/imisdocs/publications/","SubDir":0,"InternalReq":0,"LoggedInReq":0,"Disclaimer":"Disclaimer_OMA","DutchDisclaimer":null,"FileFormat":".pdf","FileDescr":"pdf","InsPub":1,"InsID":36,"FileFormID":6,"LendableFlag":1,"PublicFlag":1,"orderLib":"A","Notes":null,"AccConID":null,"AccessConstraint":null,"LicURL":null}],"litstyles":null,"thespers":null,"arch2discl":null,"SERpubls":[{"PublName":"Macmillan","City":"London"}],"MONpubls":null,"pictures":[],"thestermsPath":[{"ThesaurusTerm":"Aquaculture","ThestID":473,"Acronym":"ASFA","ThesTermPath":"Aquaculture"},{"ThesaurusTerm":"Bioaccumulation","ThestID":900,"Acronym":"ASFA","ThesTermPath":"Biological phenomena > Accumulation > Bioaccumulation"},{"ThesaurusTerm":"Histology","ThestID":4012,"Acronym":"ASFA","ThesTermPath":"Biology > Histology"},{"ThesaurusTerm":"Arsenic compounds","ThestID":554,"Acronym":"ASFA","ThesTermPath":"Chemical compounds > Arsenic compounds"},{"ThesaurusTerm":"Chlorine compounds","ThestID":1532,"Acronym":"ASFA","ThesTermPath":"Chemical compounds > Halogen compounds > Chlorine compounds"},{"ThesaurusTerm":"DDT","ThestID":2110,"Acronym":"ASFA","ThesTermPath":"Chemical compounds > Organic compounds > Hydrocarbons > Halogenated hydrocarbons > Chlorinated hydrocarbons > DDT"},{"ThesaurusTerm":"Endocrine diseases","ThestID":106666,"Acronym":"CAB","ThesTermPath":"Diseases > Organic diseases > Diseases > Endocrine diseases"},{"ThesaurusTerm":"Endocrine systems","ThestID":2768,"Acronym":"ASFA","ThesTermPath":"Endocrine systems"},{"ThesaurusTerm":"Thyroid hormones","ThestID":121664,"Acronym":"CAB","ThesTermPath":"Hormones > Thyroid hormones"},{"ThesaurusTerm":"MED, Aegean","ThestID":185819,"Acronym":"ASFA_GEOT","ThesTermPath":"MED, Aegean"},{"ThesaurusTerm":"Morphometry","ThestID":5351,"Acronym":"ASFA","ThesTermPath":"Morphometry"},{"ThesaurusTerm":"Persistence","ThestID":6093,"Acronym":"ASFA","ThesTermPath":"Persistence"},{"ThesaurusTerm":"Pollution","ThestID":6383,"Acronym":"ASFA","ThesTermPath":"Pollution"},{"ThesaurusTerm":"Pollution","ThestID":105683,"Acronym":"CAB","ThesTermPath":"Pollution"},{"ThesaurusTerm":"Polychlorinated biphenyls","ThestID":6406,"Acronym":"ASFA","ThesTermPath":"Polychlorinated biphenyls"},{"ThesaurusTerm":"Sea bass","ThestID":61759,"Acronym":"CSA","ThesTermPath":"Sea bass"},{"ThesaurusTerm":"Thyroid","ThestID":8554,"Acronym":"ASFA","ThesTermPath":"Secretory organs > Glands > Endocrine glands > Thyroid"},{"ThesaurusTerm":"Hormones","ThestID":4040,"Acronym":"ASFA","ThesTermPath":"Secretory products > Hormones"},{"ThesaurusTerm":"Sea bass","ThestID":117366,"Acronym":"CAB","ThesTermPath":"Vertebrates > Fishes > Osteichthyes > Perciformes > Serranidae > Marine fishes > Sea bass"},{"ThesaurusTerm":"Water pollution effects","ThestID":9119,"Acronym":"ASFA","ThesTermPath":"Water pollution effects"}],"thestermsASFA":[{"ThesaurusTerm":"Aquaculture"},{"ThesaurusTerm":"Arsenic compounds"},{"ThesaurusTerm":"Bioaccumulation"},{"ThesaurusTerm":"Chlorine compounds"},{"ThesaurusTerm":"DDT"},{"ThesaurusTerm":"Endocrine diseases"},{"ThesaurusTerm":"Histology"},{"ThesaurusTerm":"Hormones"},{"ThesaurusTerm":"MED, Aegean"},{"ThesaurusTerm":"Morphometry"},{"ThesaurusTerm":"Persistence"},{"ThesaurusTerm":"Pollution"},{"ThesaurusTerm":"Pollution"},{"ThesaurusTerm":"Sea bass"},{"ThesaurusTerm":"Sea bass"},{"ThesaurusTerm":"Thyroid"},{"ThesaurusTerm":"Thyroid hormones"}],"taxtermsASFA":[{"TaxTerm":"Dicentrarchus labrax"},{"TaxTerm":"Serranidae"}],"geotermsASFA":[{"GeoTerm":"Aegean Sea"}],"collections":[{"Collection":"OMA - Open Marien Archief","ShortName":"OMA"}],"conf":null,"proj":null,"Physdatasets":null,"spcols":{"222":{"SpName":"BMB - Belgische Mariene Bibliografie","SpColID":222,"ParSpColID":null,"TopParID":null,"ShortName":"BMB","URLLocation":null,"LibID":36,"OpenRepoFlag":null,"SpTypID":null,"TopParIDNotWebsite":null,"SpColPath":"BMB"},"221":{"SpName":"OMA - Open Marien Archief","SpColID":221,"ParSpColID":null,"TopParID":null,"ShortName":"OMA","URLLocation":null,"LibID":36,"OpenRepoFlag":1,"SpTypID":null,"TopParIDNotWebsite":null,"SpColPath":"OMA"}},"doi":null,"publs":null,"serparttypes":null,"monauthors":null,"MParts":null,"SParts":null,"hLibs":null,"langs":[{"BEntID":122013,"AbstractFlag":-1,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"},{"BEntID":122013,"AbstractFlag":0,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"}],"urls":[{"URL":"https://dx.doi.org/10.1016/j.marpolbul.2008.06.011","externalID":"10.1016/j.marpolbul.2008.06.011","URLTypeCode":"DOI","URLID":11394,"URLTypID":13,"URLType":"DOI","URLPrefix":"http://dx.doi.org/"}],"thesterms":[{"ThesaurusTerm":"Aquaculture","ThestID":473,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Arsenic compounds","ThestID":554,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Bioaccumulation","ThestID":900,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Chlorine compounds","ThestID":1532,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"DDT","ThestID":2110,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Endocrine diseases","ThestID":106666,"Acronym":"CAB","ThesTypID":4,"ThesType":"CAB Thesaurus"},{"ThesaurusTerm":"Endocrine systems","ThestID":2768,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Histology","ThestID":4012,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Hormones","ThestID":4040,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"MED, Aegean","ThestID":185819,"Acronym":"ASFA_GEOT","ThesTypID":34,"ThesType":"ASFA Geoterms"},{"ThesaurusTerm":"Morphometry","ThestID":5351,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Persistence","ThestID":6093,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Pollution","ThestID":6383,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Pollution","ThestID":105683,"Acronym":"CAB","ThesTypID":4,"ThesType":"CAB Thesaurus"},{"ThesaurusTerm":"Polychlorinated biphenyls","ThestID":6406,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Sea bass","ThestID":61759,"Acronym":"CSA","ThesTypID":2,"ThesType":"CSA Technology Research Database Master Thesaurus"},{"ThesaurusTerm":"Sea bass","ThestID":117366,"Acronym":"CAB","ThesTypID":4,"ThesType":"CAB Thesaurus"},{"ThesaurusTerm":"Thyroid","ThestID":8554,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Thyroid hormones","ThestID":121664,"Acronym":"CAB","ThesTypID":4,"ThesType":"CAB Thesaurus"},{"ThesaurusTerm":"Water pollution effects","ThestID":9119,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"}],"taxterms":[{"TaxTerm":"Dicentrarchus labrax [Bass]","AphiaID":126975,"TaxtID":23095},{"TaxTerm":"Serranidae [Sea basses: groupers and fairy basslets]","AphiaID":125561,"TaxtID":21535}],"geoterms":[{"GeoTerm":"Aegean Sea","GeoObjectID":3315,"GeotID":4106}],"othterms":[{"OtherTerm":"Dichloro-diphenyl-dichloroethylene","OthtID":18029},{"OtherTerm":"Endocrine disruption","OthtID":37},{"OtherTerm":"Fish species","OthtID":5833},{"OtherTerm":"Organic pollutants","OthtID":15},{"OtherTerm":"Persistent organic pollutants","OthtID":16561}],"asfacodes":null,"asfa2codes":null,"thestermsFRIS":[{"ThesaurusTerm":"Aquaculture","DutchTerm":"Aquacultuur","ThestID":473,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Arsenic compounds","DutchTerm":null,"ThestID":554,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Bioaccumulation","DutchTerm":"Bio-accumulatie","ThestID":900,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Chlorine compounds","DutchTerm":null,"ThestID":1532,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"DDT","DutchTerm":"DDT","ThestID":2110,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Endocrine diseases","DutchTerm":null,"ThestID":106666,"Acronym":"CAB","ThesTypID":4,"ThesType":"CAB Thesaurus"},{"ThesaurusTerm":"Endocrine systems","DutchTerm":"Endocriene systemen","ThestID":2768,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Histology","DutchTerm":null,"ThestID":4012,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Hormones","DutchTerm":"Hormonen","ThestID":4040,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"MED, Aegean","DutchTerm":null,"ThestID":185819,"Acronym":"ASFA_GEOT","ThesTypID":34,"ThesType":"ASFA Geoterms"},{"ThesaurusTerm":"Morphometry","DutchTerm":null,"ThestID":5351,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Persistence","DutchTerm":"Bestendigheid","ThestID":6093,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Pollution","DutchTerm":"Vervuiling","ThestID":6383,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Pollution","DutchTerm":"Pollutie","ThestID":105683,"Acronym":"CAB","ThesTypID":4,"ThesType":"CAB Thesaurus"},{"ThesaurusTerm":"Polychlorinated biphenyls","DutchTerm":"Gepolychloreerde biphenyl","ThestID":6406,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Sea bass","DutchTerm":null,"ThestID":61759,"Acronym":"CSA","ThesTypID":2,"ThesType":"CSA Technology Research Database Master Thesaurus"},{"ThesaurusTerm":"Sea bass","DutchTerm":null,"ThestID":117366,"Acronym":"CAB","ThesTypID":4,"ThesType":"CAB Thesaurus"},{"ThesaurusTerm":"Thyroid","DutchTerm":null,"ThestID":8554,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Thyroid hormones","DutchTerm":null,"ThestID":121664,"Acronym":"CAB","ThesTypID":4,"ThesType":"CAB Thesaurus"},{"ThesaurusTerm":"Water pollution effects","DutchTerm":null,"ThestID":9119,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"}],"taxtermsFRIS":[{"TaxTerm":"Dicentrarchus labrax","DutchTerm":"Zeebaars","AphiaID":126975,"TaxtID":23095},{"TaxTerm":"Serranidae","DutchTerm":null,"AphiaID":125561,"TaxtID":21535}],"geotermsFRIS":[{"GeoTerm":"Aegean Sea","DutchTerm":"Egeïsch"}],"othtermsFRIS":[{"OtherTerm":"Dichloro-diphenyl-dichloroethylene","DutchTerm":null,"OthtID":18029},{"OtherTerm":"Endocrine disruption","DutchTerm":"Endocriene verstoring","OthtID":37},{"OtherTerm":"Fish species","DutchTerm":null,"OthtID":5833},{"OtherTerm":"Organic pollutants","DutchTerm":"Organische vervuilers","OthtID":15},{"OtherTerm":"Persistent organic pollutants","DutchTerm":null,"OthtID":16561}],"resmessage":"","complete":1,"sessions":{"newSesName":"Chisala, Chilekwa, C.","newSesDate":{"date":"2008-12-04 11:17:12.813000","timezone_type":3,"timezone":"Europe/Brussels"},"updSesName":"Lyssens, Liesbeth, L.","updSesDate":{"date":"2018-05-17 20:34:05.667000","timezone_type":3,"timezone":"Europe/Brussels"}}}