{"refrec":{"BRefID":128688,"RR":"<b>Heijerick, D.G.; De Schamphelaere, K.A.C.; Van Sprang, P.A.; Janssen, C.R.<\/b> (2005). Development of a chronic zinc biotic ligand model for <i>Daphnia magna<\/i>. <i>Ecotoxicol. Environ. Saf. 62(1)<\/i>: 1-10. <a href=\"https:\/\/dx.doi.org\/10.1016\/j.ecoenv.2005.03.020\" target=\"_blank\">https:\/\/dx.doi.org\/10.1016\/j.ecoenv.2005.03.020<\/a>","BEntID":122775,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":0,"RefStringPartII":". <i>Ecotoxicol. Environ. Saf. 62(1)<\/i>: 1-10. <a href=\"https:\/\/dx.doi.org\/10.1016\/j.ecoenv.2005.03.020\" target=\"_blank\">https:\/\/dx.doi.org\/10.1016\/j.ecoenv.2005.03.020<\/a>","DocTypID":8,"DocType":"Journal article","MarineFlag":0,"FreshFlag":1,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Heijerick, D.G.; De Schamphelaere, K.A.C.; Van Sprang, P.A.; Janssen, C.R.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Heijerick, D.G. <i>et al.<\/i>","Englishabstract":"The individual effects of the cations Ca<sup>2+<\/sup>, Mg<sup>2+<\/sup>, Na<sup>+<\/sup>, and H<sup>+<\/sup> on the chronic toxicity of Zn to the waterflea <i>Daphnia magna<\/i> were investigated in different series of univariate experiments, resulting in the development of a chronic Zn biotic ligand model (BLM) for this species. Using the mathematical approach based on a linear relationship between cation activity and metal activity at the EC<sub>x<\/sub> level, the following stability constants for binding of competing cations to the biotic ligand (BL) were derived: log K<sub>CaBL<\/sub> = 3.22, log K<sub>MgBL<\/sub> = 2.69, log K<sub>NaBL<\/sub> = 1.90, and log K<sub>HBL<\/sub> = 5.77. With the derived constants and a log K<sub>ZnBL<\/sub> of 5.31, two different BLMs that predict chronic zinc toxicity (EC50, no observed effect concentration (NOEC)) for <i>D. magna<\/i> as a function of water characteristics were developed. Fractions of binding sites occupied by Zn at the considered effect levels EC50 and NOEC were 0.127 and 0.084, respectively. The NOEC-based model predicts the Zn toxicity within a factor of 2, while the chronic EC50 could be predicted within a factor of 1.5. In the future, these chronic Zn BLMs for <i>D. magna<\/i> can improve the ecological relevancy of zinc risk assessments by decreasing the bioavailability-related uncertainty of zinc toxicity.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Development of a chronic zinc biotic ligand model for <i>Daphnia magna<\/i>","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-04-15 01:31:23.044629","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":null,"Notes":null,"AnaPub":2005,"MonPub":null,"DateUpdate":"2020-10-29","DateCreate":"2009-01-21","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000230511100001","VABBcode":null,"OpenAcc":0,"DOI":"10.1016\/j.ecoenv.2005.03.020"},"refs":null,"anarec":{"AnaID":128688,"PubliDate":2005,"Pagination":"1-10","XtraPublOfAnaID":null,"ISBN":null,"Volume":"62","Issue":"1","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":42636,"SerRR":"Ecotoxicology and Environmental Safety. 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