{"refrec":{"BRefID":128834,"RR":"<b>Heijerick, D.G.; De Schamphelaere, K.A.C.; Janssen, C.R.<\/b> (2002). Predicting acute zinc toxicity for <i>Daphnia magna<\/i> as a function of key water chemistry characteristics: Development and validation of a biotic ligand model. <i>Environ. Toxicol. Chem. 21(6)<\/i>: 1309-1315. <a href=\"https:\/\/dx.doi.org\/10.1897\/1551-5028(2002)021<1309:PAZTFD>2.0.CO;2\" target=\"_blank\">https:\/\/dx.doi.org\/10.1897\/1551-5028(2002)021<1309:PAZTFD>2.0.CO;2<\/a>","BEntID":122917,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":null,"RefStringPartII":". <i>Environ. Toxicol. Chem. 21(6)<\/i>: 1309-1315. <a href=\"https:\/\/dx.doi.org\/10.1897\/1551-5028(2002)021<1309:PAZTFD>2.0.CO;2\" target=\"_blank\">https:\/\/dx.doi.org\/10.1897\/1551-5028(2002)021<1309:PAZTFD>2.0.CO;2<\/a>","DocTypID":8,"DocType":"Journal article","MarineFlag":0,"FreshFlag":1,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Heijerick, D.G.; De Schamphelaere, K.A.C.; Janssen, C.R.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Heijerick, D.G.; De Schamphelaere, K.A.C.; Janssen, C.R.","Englishabstract":"The individual effect of different major cations (Ca<sup>2+<\/sup>, Mg<sup>2+<\/sup>, Na<sup>+<\/sup>, K<sup>+<\/sup>, and H<sup>+<\/sup>) on the acute toxicity of zinc to the waterflea <i>Daphnia magna<\/i> was investigated. The 48-h median effective concentration (EC50) in the baseline test medium (i.e., a standard medium with very low ion concentrations) was about 6 \u03bcM (Zn<sup>2+<\/sup>). An increase of Ca<sup>2+<\/sup> (from 0.25 mM to 3 mM), Mg<sup>2+<\/sup> (from 0.25 mM to 2 mM), and Na<sup>+<\/sup> activity (from 0.077 mM to 13 mM) reduced zinc toxicity by a factor of 6.3, 2.1, and 3.1, respectively. No further toxicity reduction was observed when Ca<sup>2+<\/sup> and Mg<sup>2+<\/sup> activities exceeded 3.0 and 2.0 mM, respectively. Both K<sup>+<\/sup> and H<sup>+<\/sup> did not significantly alter zinc toxicity (expressed as Zn<sup>2+<\/sup> activity). From these data, conditional stability constants for Ca<sup>2+<\/sup> (log K = 3.24), Mg<sup>2+<\/sup> (log K = 2.97), Na<sup>+<\/sup> (log K = 2.16), and Zn<sup>2+<\/sup> (log K = 5.31) were derived and incorporated into a biotic ligand model (BLM) predicting acute zinc toxicity to <i>D. magna<\/sup> in surface waters with different water quality characteristics. Validation of the developed BLM using 17 media with different pH, hardness, and dissolved organic carbon (DOC) content resulted in a significant correlation coefficient (R<sup>2<\/sup> = 0.76) between predicted and observed 48-h EC50. Eighty-eight percent of the predictions were within a factor of 1.3 of the observed 48-h EC50.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Predicting acute zinc toxicity for <i>Daphnia magna<\/i> as a function of key water chemistry characteristics: Development and validation of a biotic ligand model","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-04-16 01:31:37.243726","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":null,"Notes":null,"AnaPub":2002,"MonPub":null,"DateUpdate":"2009-01-23","DateCreate":"2009-01-23","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000175874300028","VABBcode":null,"OpenAcc":0,"DOI":"10.1897\/1551-5028(2002)021<1309:PAZTFD>2.0.CO;2"},"refs":null,"anarec":{"AnaID":128834,"PubliDate":2002,"Pagination":"1309-1315","XtraPublOfAnaID":null,"ISBN":null,"Volume":"21","Issue":"6","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":42839,"SerRR":"Environmental Toxicology and Chemistry. Setac Press: New York.  ISSN 0730-7268; e-ISSN 1552-8618","StandardTitleSer":"Environmental Toxicology and Chemistry","ISSN":"0730-7268","AbbrevSer":"Environ. Toxicol. Chem.","StandardTitleMon":null,"StartPage":1309,"Pages":7,"ToPubliDate":null,"BRefBibLvlCode":"S","SerNotes":null},"monrec":null,"serrec":null,"relations":null,"relationsRev":null,"addrec":null,"othpubs":null,"ownerships":null,"authors":[{"AutName":"Heijerick","Firstname":null,"Initials":"D.G.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":122917,"AutID":11744,"OrderNr":1,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":2825,"InsID":null},{"AutName":"De Schamphelaere","Firstname":"Karel","Initials":"K.A.C.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":122917,"AutID":11752,"OrderNr":2,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":"0000-0002-5063-922X","PersID":2823,"InsID":null},{"AutName":"Janssen","Firstname":"Colin","Initials":"C.R.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":122917,"AutID":11628,"OrderNr":3,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":"0000-0002-7781-6679","PersID":50,"InsID":null}],"mapdetails":null,"datasets":null,"monographs":null,"monparts":null,"serparts":null,"BEntOpen":null,"BEntPrivate":null,"availability":null,"litstyles":null,"thespers":null,"arch2discl":null,"SERpubls":[{"PublName":"Setac Press","City":"New York"}],"MONpubls":null,"pictures":[],"thestermsPath":[{"ThesaurusTerm":"Stability constants","ThestID":7944,"Acronym":"ASFA","ThesTermPath":"Constants > Stability constants"},{"ThesaurusTerm":"Toxicity","ThestID":85524,"Acronym":"CSA","ThesTermPath":"Toxicity"}],"thestermsASFA":[{"ThesaurusTerm":"Stability constants"},{"ThesaurusTerm":"Toxicity"}],"taxtermsASFA":[{"TaxTerm":"Daphnia magna"}],"geotermsASFA":null,"collections":[{"Collection":"Section Ecotox","ShortName":"Ecotox"}],"conf":null,"proj":null,"Physdatasets":null,"spcols":{"476":{"SpName":"Section Ecotox","SpColID":476,"ParSpColID":null,"TopParID":null,"ShortName":"Ecotox","URLLocation":null,"LibID":null,"OpenRepoFlag":null,"SpTypID":null,"TopParIDNotWebsite":null,"SpColPath":"Ecotox"}},"doi":null,"publs":null,"serparttypes":null,"monauthors":null,"MParts":null,"SParts":null,"hLibs":null,"langs":[{"BEntID":122917,"AbstractFlag":0,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"}],"urls":[{"URL":"https:\/\/dx.doi.org\/10.1897\/1551-5028(2002)021<1309:PAZTFD>2.0.CO;2","externalID":"10.1897\/1551-5028(2002)021<1309:PAZTFD>2.0.CO;2","URLTypeCode":"DOI","URLID":112406,"URLTypID":13,"URLType":"DOI","URLPrefix":"http:\/\/dx.doi.org\/"}],"thesterms":[{"ThesaurusTerm":"Stability constants","ThestID":7944,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Toxicity","ThestID":85524,"Acronym":"CSA","ThesTypID":2,"ThesType":"CSA Technology Research Database Master Thesaurus"}],"taxterms":[{"TaxTerm":"Daphnia magna","AphiaID":148372,"TaxtID":28498}],"geoterms":null,"othterms":[{"OtherTerm":"Biotic ligand model","OthtID":5275}],"asfacodes":null,"asfa2codes":null,"thestermsFRIS":[{"ThesaurusTerm":"Stability constants","DutchTerm":null,"ThestID":7944,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Toxicity","DutchTerm":null,"ThestID":85524,"Acronym":"CSA","ThesTypID":2,"ThesType":"CSA Technology Research Database Master Thesaurus"}],"taxtermsFRIS":[{"TaxTerm":"Daphnia magna","DutchTerm":"Watervlo","AphiaID":148372,"TaxtID":28498}],"geotermsFRIS":null,"othtermsFRIS":[{"OtherTerm":"Biotic ligand model","DutchTerm":null,"OthtID":5275}],"resmessage":"","complete":1,"sessions":{"newSesName":"Dewitte, Elien, E.","newSesDate":{"date":"2009-01-23 08:56:32.087000","timezone_type":3,"timezone":"Europe\/Brussels"},"updSesName":"Dewitte, Elien, E.","updSesDate":{"date":"2009-01-23 08:56:32.087000","timezone_type":3,"timezone":"Europe\/Brussels"}}}