{"refrec":{"BRefID":135242,"RR":"<b>Dixon, D.R.; Clarke, K.R.</b> (1982). Sister chromatid exchange: A sensitive method for detecting damage caused by exposure to environmental mutagens in the chromosomes of adult <i>Mytilus edulis</i>. <i>Mar. biol. lett. 3(3)</i>: 163-172","BEntID":129140,"PublicFlag":1,"CheckedFlag":0,"wosflag":0,"vabbflag":null,"RefStringPartII":". <i>Mar. Biol. Lett. 3(3)</i>: 163-172","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Dixon, D.R.; Clarke, K.R.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Dixon, D.R.; Clarke, K.R.","Englishabstract":"Dose-response curves are presented for the frequencies of sister chromatid exchange (SCE) and structural chromosomal aberrations in cells from gills of <i>Mytilus edulis</i> exposed, in vivo, to differing concentrations of mitomycin C (MMC). Appropriate statistical methodology is derived for the resulting Poisson and binomially distributed counts, in the presence of between-animal variation. Both SCE and structural abnormalities increased in frequency with higher mutagen levels, but greater sensitivity is demonstrated for SCE. SCE frequency in controls, 4.1 per metaphase, is similar to baseline levels quoted for other aquatic organisms. This novel application of the SCE technique to a somatic tissue in <i>Mytilus</i> , an important species in pollution research, represents a significant advance towards the development of a cytogenetic method for detecting and monitoring genotoxic pollutants in the marine environment.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Sister chromatid exchange: A sensitive method for detecting damage caused by exposure to environmental mutagens in the chromosomes of adult <i>Mytilus edulis</i>","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2024-12-10 01:33:17.368041","timezone_type":1,"timezone":"+01:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":null,"Notes":null,"AnaPub":1982,"MonPub":null,"DateUpdate":"2009-05-11","DateCreate":"2009-05-11","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":null,"VABBcode":null,"OpenAcc":0},"refs":null,"anarec":{"AnaID":135242,"PubliDate":1982,"Pagination":"163-172","XtraPublOfAnaID":null,"ISBN":null,"Volume":"3","Issue":"3","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":45356,"SerRR":"Marine Biology Letters. 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