{"refrec":{"BRefID":141913,"RR":"<b>Galindo, J.; Martínez-Fernández, M.; Suárez, P.; Móran, P.; San Juan, F.; Rolán-Alvarez, E.</b> (2009). The adaptive role of <i>Phosphoglucomutase</i> and other allozymes in a marine snail across the vertical rocky-shore gradient. <i>Biol. J. Linn. Soc. 98(1)</i>: 225-233. <a href=\"https://dx.doi.org/10.1111/j.1095-8312.2009.01272.x\" target=\"_blank\">https://dx.doi.org/10.1111/j.1095-8312.2009.01272.x</a>","BEntID":135187,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":0,"RefStringPartII":". <i>Biol. J. Linn. Soc. 98(1)</i>: 225-233. <a href=\"https://dx.doi.org/10.1111/j.1095-8312.2009.01272.x\" target=\"_blank\">https://dx.doi.org/10.1111/j.1095-8312.2009.01272.x</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Galindo, J.; Martínez-Fernández, M.; Suárez, P.; Móran, P.; San Juan, F.; Rolán-Alvarez, E.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Galindo, J. <i>et al.</i>","Englishabstract":"Natural selection can play an important role in the maintenance of genetic polymorphisms, despite ongoing gene flow. In the present study, we use previously analysed allozymic loci and perform an <i>F</i><sub>ST</sub> outlier-based analysis to detect the signatures of divergent selection between sympatric ecotypes of the marine snail <i>Littorina saxatilis</i> at different localities. The results obtained show that different allozyme polymorphisms are affected (directly or indirectly) by selection at distinct geographical regions. The <i>Phosmogluco mutase-2</i> locus was the best candidate for adaptation and further biochemical analyses were performed. The kinetic properties of the three more common genotypes of <i>Pgm-2</i> were studied. The results obtained are concordant with two alternative hypotheses: (1) natural selection is acting directly on this locus or, more probably, (2) selection is affecting a genomic region tightly linked to the enzyme locus. In both cases, the known existence of a parallel and partially independent origin of these ecotypes would explain why different candidate loci were detected in different localities.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"The adaptive role of <i>Phosphoglucomutase</i> and other allozymes in a marine snail across the vertical rocky-shore gradient","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-06-14 01:31:19.297801","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"candidate loci; divergent natural selection; F(ST); kinetic properties;outliers","OtherDescriptors":null,"Notes":null,"AnaPub":2009,"MonPub":null,"DateUpdate":"2020-09-07","DateCreate":"2009-11-06","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000269315600021","VABBcode":null,"OpenAcc":1,"DOI":"10.1111/j.1095-8312.2009.01272.x"},"refs":null,"anarec":{"AnaID":141913,"PubliDate":2009,"Pagination":"225-233","XtraPublOfAnaID":null,"ISBN":null,"Volume":"98","Issue":"1","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":42441,"SerRR":"Biological Journal of the Linnean Society. 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