{"refrec":{"BRefID":1735,"RR":"<b>De Jong-Brink, M.; Hoek, R.M.; Smit, A.B.; Bergamin-Sassen, M.J.M.; Lageweg, W.</b> (1995). Schistosoma parasites evoke stress responses in their snail host by a cytokine-like factor interfering with neuro-endocrine mechanisms. <i>Neth. J. Zool. 45(1-2)</i>: 113-116","BEntID":1735,"PublicFlag":1,"CheckedFlag":0,"wosflag":null,"vabbflag":null,"RefStringPartII":". <i>Neth. J. Zool. 45(1-2)</i>: 113-116","DocTypID":8,"DocType":"Journal article","MarineFlag":0,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"De Jong-Brink, M.; Hoek, R.M.; Smit, A.B.; Bergamin-Sassen, M.J.M.; Lageweg, W.","OrigTitleTranslFlag":0,"Authorstringtrunc":"De Jong-Brink, M. <i>et al.</i>","Englishabstract":"Results obtained with the model <i>Trichobilharzia ocellata-Lymnaea stagnalis</i> confirm the hypothesis that schistosome parasites evoke physiological effects in their snail host-castration and giant growth-by interfering with neuroendocrine systems (NES) regulating the physiological processes concerned. In the haemolymph of the snail host a factor, called <i>schistosomin</i>, was found acting at both the central and the peripheral parts of NES involved in regulation of reproduction and growth. Schistosomin appears to be a host-derived factor, probably released by haemocytes and cells in the connective tissue. It meets the criteria of being a cytokine-like factor, which accounts for its interference with NES. 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