{"refrec":{"BRefID":1887,"RR":"<b>Kühn, E.R.; Mol, K.; Darras, V.M.</b> (1995). Peripheral deiodination of thyroid hormones: biological significance. <i>Neth. J. Zool. 45(1-2)</i>: 135-139","BEntID":1887,"PublicFlag":1,"CheckedFlag":0,"wosflag":null,"vabbflag":null,"RefStringPartII":". <i>Neth. J. Zool. 45(1-2)</i>: 135-139","DocTypID":8,"DocType":"Journal article","MarineFlag":0,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Kühn, E.R.; Mol, K.; Darras, V.M.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Kühn, E.R.; Mol, K.; Darras, V.M.","Englishabstract":"The main secretory of the thyroid gland is thyroxine (T <sub>4</sub>), which is a relatively inactive prohormone serving as a substrate for deiodination processes in peripheral presence of outer-ring (ORD) and inner-ring deiodinases (IRD), respectively. During ontogenesis high plasma levels of (T<sub>3</sub>) occurs in the presence of outer-ring (ORD) and inner-ring deiodinases (IRD), respectively. During ontogenesis high plasma levels of T <sub>3</sub>occur at parturition or hatching in precocial mammals and birds and at metamorphic climax in amphibians. These high levels may be obtainedby increased T<sub>4</sub> ORD activity and olso by decreased T<sub>3</sub> degradation. In mammals, birth and fish growth hormone (GH) has been described as stimulatory agent for ORD activity. In the chick ombryo, GH does not increase the ammount of T<sub>4</sub> ORD but inhibits T<sub>3</sub>IRD activity and T<sub>3</sub> degradation.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Peripheral deiodination of thyroid hormones: biological significance","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2024-12-10 01:33:17.368041","timezone_type":1,"timezone":"+01:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":null,"Notes":null,"AnaPub":1995,"MonPub":null,"DateUpdate":"2000-08-24","DateCreate":"2000-08-24","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:A1995RY90400032","VABBcode":null,"OpenAcc":0},"refs":null,"anarec":{"AnaID":1887,"PubliDate":1995,"Pagination":"135-139","XtraPublOfAnaID":null,"ISBN":null,"Volume":"45","Issue":"1-2","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":43566,"SerRR":"Netherlands Journal of Zoology. E.J. Brill: Leiden.  ISSN 0028-2960; e-ISSN 1568-542X","StandardTitleSer":"Netherlands Journal of Zoology","ISSN":"0028-2960","AbbrevSer":"Neth. J. Zool.","StandardTitleMon":null,"StartPage":135,"Pages":5,"ToPubliDate":null,"BRefBibLvlCode":"S","SerNotes":null},"monrec":null,"serrec":null,"relations":null,"relationsRev":null,"addrec":null,"othpubs":null,"ownerships":null,"authors":[{"AutName":"Kühn","Firstname":"Eduard","Initials":"E.R.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":1887,"AutID":3110,"OrderNr":1,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Mol","Firstname":null,"Initials":"K.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":1887,"AutID":3621,"OrderNr":2,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Darras","Firstname":"Veerle","Initials":"V.M.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":1887,"AutID":3108,"OrderNr":3,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null}],"mapdetails":null,"datasets":null,"monographs":null,"monparts":null,"serparts":null,"BEntOpen":null,"BEntPrivate":null,"availability":null,"litstyles":null,"thespers":null,"arch2discl":null,"SERpubls":[{"PublName":"E.J. Brill","City":"Leiden"}],"MONpubls":null,"pictures":[],"thestermsPath":null,"thestermsASFA":null,"taxtermsASFA":null,"geotermsASFA":null,"collections":null,"conf":null,"proj":null,"Physdatasets":null,"spcols":null,"doi":null,"publs":null,"serparttypes":null,"monauthors":null,"MParts":null,"SParts":null,"hLibs":null,"langs":[{"BEntID":1887,"AbstractFlag":0,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"}],"urls":null,"thesterms":null,"taxterms":null,"geoterms":null,"othterms":null,"asfacodes":null,"asfa2codes":null,"thestermsFRIS":null,"taxtermsFRIS":null,"geotermsFRIS":null,"othtermsFRIS":null,"resmessage":"","complete":1,"sessions":{"newSesName":"VLIZ2000\\Stefaan","newSesDate":{"date":"2000-08-24 19:15:10.000000","timezone_type":3,"timezone":"Europe/Brussels"},"updSesName":"VLIZ2000\\Stefaan","updSesDate":{"date":"2000-08-24 19:15:10.000000","timezone_type":3,"timezone":"Europe/Brussels"}}}