{"refrec":{"BRefID":203538,"RR":"<b>Baussant, T.; Bechmann, R.K.; Taban, I.C.; Larsen, B.K.; Tandberg, A.H.; Bjornstad, A.; Torgrimsen, S.; Naevdal, A.; Øysaed, K.B.; Jonsson, G.; Sanni, S.</b> (2009). Enzymatic and cellular responses in relation to body burden of PAHs in bivalve molluscs: A case study with chronic levels of North Sea and Barents Sea dispersed oil. <i>Mar. Pollut. Bull. 58(12)</i>: 1796-1807. <a href=\"https://dx.doi.org/10.1016/j.marpolbul.2009.08.007\" target=\"_blank\">https://dx.doi.org/10.1016/j.marpolbul.2009.08.007</a>","BEntID":195741,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":1,"RefStringPartII":". <i>Mar. Pollut. Bull. 58(12)</i>: 1796-1807. <a href=\"https://dx.doi.org/10.1016/j.marpolbul.2009.08.007\" target=\"_blank\">https://dx.doi.org/10.1016/j.marpolbul.2009.08.007</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Baussant, T.; Bechmann, R.K.; Taban, I.C.; Larsen, B.K.; Tandberg, A.H.; Bjornstad, A.; Torgrimsen, S.; Naevdal, A.; Øysaed, K.B.; Jonsson, G.; Sanni, S.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Baussant, T. <i>et al.</i>","Englishabstract":"<i>Mytilus edulis</i> and <i>Chlamys islandica</i> were exposed to nominal dispersed crude oil concentrations in the range 0.015–0.25 mg/l for one month. Five biomarkers (enzymatic and cellular responses) were analysed together with bioaccumulation of PAHs at the end of exposure. In both species, PAH tissue residues reflected the exposure concentration measured in the water and lipophylicity determined the bioaccumulation levels. Oil caused biomarker responses in both species but more significant alterations in exposed <i>C. islandica</i> were observed. The relationships between exposure levels and enzymatic responses were apparently complex. The integrated biomarker response related against the exposure levels was U-shaped in both species and no correlation with total PAH body burden was found. For the monitoring of chronic offshore discharges, dose- and time-related events should be evaluated in the selection of biomarkers to apply. 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