{"refrec":{"BRefID":204514,"RR":"<b>Pillet, S.; Pereira, A.; Braekman, J.C.; Houvenaghel, G.</b> (1995). Patterns in long term accumulation of okadaic acid and DTX1 in blue mussels, <i>Mytilus edulis</i>, experimentally fed with the DSP-containing alga, <i>Prorocentrum lima</i>, <b><i>in</i></b>: Lassus, P. <i>et al.</i> (Ed.) <i>Harmful marine algal blooms: Proceedings of the Sixth International Conference on toxic marine phytoplankton = Proliférations d'algues marines nuisibles: Sixiéme Conférence Internationale sur le phytoplancton toxique, October 18-22, 1993, Nantes, France.</i> pp. 487-492","BEntID":196689,"PublicFlag":1,"CheckedFlag":0,"wosflag":null,"vabbflag":null,"RefStringPartII":", <b><i>in</i></b>: Lassus, P. <i>et al.</i> <i>Harmful marine algal blooms: Proceedings of the Sixth International Conference on toxic marine phytoplankton = Proliférations d'algues marines nuisibles: Sixiéme Conférence Internationale sur le phytoplancton toxique, October 18-22, 1993, Nantes, France.</i> pp. 487-492","DocTypID":17,"DocType":"Book chapters","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Pillet, S.; Pereira, A.; Braekman, J.C.; Houvenaghel, G.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Pillet, S. <i>et al.</i>","Englishabstract":"DSP accumulation in mussels has been little investigated. In the experiments reported here, we analysed long term DSP mussel contamination. Mussels were acclimatised and maintained in vitro to be submitted to daily rations of <i>Prorocentrum lima</i>. Okadaic acid (OA) and DTX1 contents in hepatopancreas, and whole mussels were measured by HPLC. A slow build-up with toxin contents from 1.2 to 2.0 µg.g<sup>-1</sup>) wet weight hepatopancreas occurred until day 14, followed by a peak of 3.8 µg.g<sup>-1</sup>) on day 16 with a rapid decrease thereafter to previous. Values. This set of triplicate analyses clearly showed that the accumulation of OA and DTX1 in hepatopancreas did not respond as a progressive long term build-up under our experimental conditions. This pattern in toxin accumulation may be the result of toxin bioconversions and/or feeding behaviour modifications induced by the presence of <i>P. lima</i>. Hepatopancreas OA and DTX1 content changed similarly with time and in the same ratio as in <i>P. lima</i> cells. It seems thus that these two toxins were involved together in the same metabolic reactions and that no bioconversions occurred between them. Such kinetics could lead to delayed development of contamination in natural waters, where mussels might then exhibit sanitary risks many days after the beginning of exposure to a long period of low toxicity. No mussel mortality occurred during the whole of this contamination experiment.","AbstractOtherLang":null,"BibLvlCode":"AM","StandardTitle":"Patterns in long term accumulation of okadaic acid and DTX1 in blue mussels, <i>Mytilus edulis</i>, experimentally fed with the DSP-containing alga, <i>Prorocentrum lima</i>","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2024-12-10 01:33:17.368041","timezone_type":1,"timezone":"+01:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"Bivalvia","OtherDescriptors":null,"Notes":null,"AnaPub":1995,"MonPub":null,"DateUpdate":"2011-04-27","DateCreate":"2011-04-27","SecASFANote":null,"ConfID":null,"PeerRev":null,"VlizCoreFlag":1,"WoScode":null,"VABBcode":null,"OpenAcc":0},"refs":null,"anarec":{"AnaID":204514,"PubliDate":1995,"Pagination":"487-492","XtraPublOfAnaID":null,"ISBN":"2-85206-972-5","Volume":null,"Issue":null,"BRefMon":136231,"BRefMonRR":"<b>Lassus, P. <i>et al.</i></b> (1995). Harmful marine algal blooms: Proceedings of the Sixth International Conference on toxic marine phytoplankton = Proliférations d'algues marines nuisibles: Sixiéme Conférence Internationale sur le phytoplancton toxique, October 18-22, 1993, Nantes, France. Intercept/Technique et Documentation - Lavoisier: Paris. ISBN 2-85206-972-5. 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