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Spaniodon shows the synapomorphies of clupeocephalans, protacanthopterygians and salmoniforms. Its relationships among salmoniforms are still undecided, although it could be closely related to the Osmeroidei. The main character that supports this grouping is the dermal part of the mesethmoid formed by the partial fusion of a pair of lateral dermethmoids, whereas the rostral is absent. 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