{"refrec":{"BRefID":23463,"RR":"<b>Lacoste, A.; Jalabert, F.; Malham, S.; Cueff, A.; Gélébart, F.; Cordevant, C.; Lange, M.; Poulet, S.A.</b> (2001). A <i>Vibrio splendidus</i> strain is associated with summer mortality of juvenile oysters <i>Crassostrea gigas</i> in the Bay of Morlaix (North Brittany, France). <i>Dis. Aquat. Org. 46</i>: 139-145. <a href=\"https://dx.doi.org/10.3354/dao046139\" target=\"_blank\">https://dx.doi.org/10.3354/dao046139</a>","BEntID":23463,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":null,"RefStringPartII":". <i>Dis. Aquat. Org. 46</i>: 139-145. <a href=\"https://dx.doi.org/10.3354/dao046139\" target=\"_blank\">https://dx.doi.org/10.3354/dao046139</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Lacoste, A.; Jalabert, F.; Malham, S.; Cueff, A.; Gélébart, F.; Cordevant, C.; Lange, M.; Poulet, S.A.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Lacoste, A. <i>et al.</i>","Englishabstract":"Juvenile oysters <i>Crassostrea gigas</i> cultured in the Bay of Morlaix (France) have suffered unexplained summer mortalities for over a decade. In the present study, we tested the hypothesis that a bacterial pathogen could be responsible for this phenomenon. A first attempt failed to isolate a bacterial pathogen from moribund or weak oysters. Only non-pathogenic, probably opportunistic, bacteria were isolated. As an alternative approach, we focused on oysters presenting reduced stress-response capacities (determined by circulating noradrenaline measurements), a characteristic of juvenile oysters entering an early phase of the disease. Cultures of bacterial isolates on TCBS plates revealed that a <i>Vibrio</i> strain was present in diseased oysters and scarce or absent in healthy oysters. Experimental infections indicated that this <i>Vibrio</i> can cause mortalities of juvenile oysters when injected at concentrations ranging from 10<sup>4</sup> to 10<sup>8</sup> CFU oyster<sup>-1</sup>. Similarly to the summer mortality disease, the <i>Vibrio</i> isolate caused higher mortalities at higher temperatures; apparently, it could not be transmitted horizontally, it did not affect adult oysters and it induced stress-response dysfunctions in juvenile oysters. Phenotypic and genotypic characterizations identified the pathogen as <i>Vibrio splendidus</i>. Taken together, the present results satisfy Koch’s postulate and suggest that this bacterial strain is probably responsible for the juvenile oyster summer mortalities in the Bay of Morlaix.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"A <i>Vibrio splendidus</i> strain is associated with summer mortality of juvenile oysters <i>Crassostrea gigas</i> in the Bay of Morlaix (North Brittany, France)","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-05-30 01:31:02.212305","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":"<i>Crassostrea gigas</i>; summer mortality; juveniles; <i>Vibrio splendidus</i>; stress; Noradrelanine","Notes":null,"AnaPub":2001,"MonPub":null,"DateUpdate":"2014-08-25","DateCreate":"2002-03-18","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000172266600008","VABBcode":null,"OpenAcc":1,"DOI":"10.3354/dao046139"},"refs":null,"anarec":{"AnaID":23463,"PubliDate":2001,"Pagination":"139-145","XtraPublOfAnaID":null,"ISBN":null,"Volume":"46","Issue":null,"BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":42792,"SerRR":"Diseases of Aquatic Organisms. 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