{"refrec":{"BRefID":247012,"RR":"<b>Lebbe, E.K.M.; Peigneur, S.; Wijesekara, I.; Tytgat, J.</b> (2014). Conotoxins targeting nicotinic acetylcholine receptors: an overview. <i>Mar. Drugs 12(5)</i>: 2970-3004. <a href=\"http://dx.doi.org/10.3390/md12052970\" target=\"_blank\">dx.doi.org/10.3390/md12052970</a>","BEntID":238712,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":null,"RefStringPartII":". <i>Mar. Drugs 12(5)</i>: 2970-3004. <a href=\"https://dx.doi.org/10.3390/md12052970\" target=\"_blank\">https://dx.doi.org/10.3390/md12052970</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Lebbe, E.K.M.; Peigneur, S.; Wijesekara, I.; Tytgat, J.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Lebbe, E.K.M. <i>et al.</i>","Englishabstract":"Marine snails of the genus <i>Conus</i> are a large family of predatory gastropods with an unparalleled molecular diversity of pharmacologically active compounds in their venom. Cone snail venom comprises of a rich and diverse cocktail of peptide toxins which act on a wide variety of ion channels such as voltage-gated sodium- (Na<sub>V</sub>), potassium- (K<sub>V</sub>), and calcium- (Ca<sub>V</sub>) channels as well as nicotinic acetylcholine receptors (nAChRs) which are classified as ligand-gated ion channels. 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