{"refrec":{"BRefID":248078,"RR":"<b>Oren, M.; Tarrant, A.M.; Alon, S.; Simon-Blecher, N.; Elbaz, I.; Appelbaum, L.; Levy, O.</b> (2015). Profiling molecular and behavioral circadian rhythms in the non-symbiotic sea anemone <i>Nematostella vectensis</i>. <i>NPG Scientific Reports 5(11418)</i>: 15 pp. <a href=\"http://dx.doi.org/10.1038/srep11418\" target=\"_blank\">http://dx.doi.org/10.1038/srep11418</a>","BEntID":239782,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":1,"RefStringPartII":". <i>NPG Scientific Reports 5(11418)</i>: 15 pp. <a href=\"http://dx.doi.org/10.1038/srep11418\" target=\"_blank\">http://dx.doi.org/10.1038/srep11418</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Oren, M.; Tarrant, A.M.; Alon, S.; Simon-Blecher, N.; Elbaz, I.; Appelbaum, L.; Levy, O.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Oren, M. <i>et al.</i>","Englishabstract":"Endogenous circadian clocks are poorly understood within early-diverging animal lineages. We have characterized circadian behavioral patterns and identified potential components of the circadian clock in the starlet sea anemone, <i>Nematostella vectensis</i>: a model cnidarian which lacks algal symbionts. Using automatic video tracking we showed that <i>Nematostella</i> exhibits rhythmic circadian locomotor activity, which is persistent in constant dark, shifted or disrupted by external dark/light cues and maintained the same rate at two different temperatures. This activity was inhibited by a casein kinase 1d/e inhibitor, suggesting a role for CK1 homologue(s) in Nematostella clock. Using high-throughput sequencing we profiled <i>Nematostella</i> transcriptomes over 48?hours under a light-dark cycle. We identified 180 Nematostella diurnally-oscillated transcripts and compared them with previously established databases of adult and larvae of the symbiotic coral <i>Acropora millepora</i>, revealing both shared homologues and unique rhythmic genes. Taken together, this study further establishes <i>Nematostella</i> as a non-symbiotic model organism to study circadian rhythms and increases our understanding about the fundamental elements of circadian regulation and their evolution within the Metazoa.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Profiling molecular and behavioral circadian rhythms in the non-symbiotic sea anemone <i>Nematostella vectensis</i>","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-06-15 01:32:43.580936","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":null,"Notes":null,"AnaPub":2015,"MonPub":null,"DateUpdate":"2018-02-13","DateCreate":"2015-06-26","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000356521800001","VABBcode":null,"OpenAcc":1,"DOI":"10.1038/srep11418"},"refs":null,"anarec":{"AnaID":248078,"PubliDate":2015,"Pagination":"15 pp","XtraPublOfAnaID":null,"ISBN":null,"Volume":"5","Issue":"11418","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":208093,"SerRR":"Scientific Reports (Nature Publishing Group). 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