{"refrec":{"BRefID":257378,"RR":"<b>Verhelst, B.; Van de Peer, Y.; Rouzé, P.</b> (2013). The complex intron landscape and massive intron invasion in a picoeukaryote provides insights into intron evolution. <i>Genome Biology and Evolution 5(12)</i>: 2393-2401. <a href=\"http://dx.doi.org/10.1093/gbe/evt189\" target=\"_blank\">dx.doi.org/10.1093/gbe/evt189</a>","BEntID":249387,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":null,"RefStringPartII":". <i>Genome Biology and Evolution 5(12)</i>: 2393-2401. <a href=\"https://dx.doi.org/10.1093/gbe/evt189\" target=\"_blank\">https://dx.doi.org/10.1093/gbe/evt189</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Verhelst, B.; Van de Peer, Y.; Rouzé, P.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Verhelst, B. <i>et al.</i>","Englishabstract":"Genes in pieces and spliceosomal introns are a landmark of eukaryotes, with intron invasion usually assumed to have happened early on in evolution. Here, we analyze the intron landscape of Micromonas, a unicellular green alga in the Mamiellophyceae lineage, demonstrating the coexistence of several classes of introns and the occurrence of recent massive intron invasion. This study focuses on two strains, CCMP1545 and RCC299, and their related individuals from ocean samplings, showing that they not only harbor different classes of introns depending on their location in the genome, as for other Mamiellophyceae, but also uniquely carry several classes of repeat introns. These introns, dubbed introner elements (IEs), are found at novel positions in genes and have conserved sequences, contrary to canonical introns. This IE invasion has a huge impact on the genome, doubling the number of introns in the CCMP1545 strain. We hypothesize that each IE class originated from a single ancestral IE that has been colonizing the genome after strain divergence by inserting copies of itself into genes by intron transposition, likely involving reverse splicing. Along with similar cases recently observed in other organisms, our observations in Micromonas strains shed a new light on the evolution of introns, suggesting that intron gain is more widespread than previously thought.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"The complex intron landscape and massive intron invasion in a picoeukaryote provides insights into intron evolution","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2024-12-10 01:33:17.368041","timezone_type":1,"timezone":"+01:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"intron evolution; intron gain; Mamiellophyceae; Micromonas; intronerelements","OtherDescriptors":null,"Notes":null,"AnaPub":2013,"MonPub":null,"DateUpdate":"2016-06-21","DateCreate":"2016-05-29","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000329250400012","VABBcode":null,"OpenAcc":1,"DOI":"10.1093/gbe/evt189"},"refs":null,"anarec":{"AnaID":257378,"PubliDate":2013,"Pagination":"2393-2401","XtraPublOfAnaID":null,"ISBN":null,"Volume":"5","Issue":"12","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":255059,"SerRR":"Genome Biology and Evolution. Oxford University Press: Oxford.  ISSN 1759-6653; e-ISSN 1759-6653","StandardTitleSer":"Genome Biology and Evolution","ISSN":"1759-6653","AbbrevSer":null,"StandardTitleMon":null,"StartPage":2393,"Pages":9,"ToPubliDate":null,"BRefBibLvlCode":"S","SerNotes":null},"monrec":null,"serrec":null,"relations":null,"relationsRev":null,"addrec":null,"othpubs":null,"ownerships":null,"authors":[{"AutName":"Verhelst","Firstname":"Bram","Initials":"B.","Affiliation":"Department of Plant Biotechnology and Bioinformatics, Ghent University","Discriminator":null,"CorporateFlag":0,"BEntID":249387,"AutID":198386,"OrderNr":1,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":"Universiteit Gent; Faculteit Wetenschappen; Vakgroep Plantenbiotechnologie en Bio-informatica","ORCID":null,"PersID":31561,"InsID":12197},{"AutName":"Van de Peer","Firstname":"Yves","Initials":"Y.","Affiliation":"Department of Plant Biotechnology and Bioinformatics, Ghent University","Discriminator":null,"CorporateFlag":0,"BEntID":249387,"AutID":181496,"OrderNr":2,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":"Universiteit Gent; Faculteit Wetenschappen; Vakgroep Plantenbiotechnologie en Bio-informatica","ORCID":"0000-0003-4327-3730","PersID":19015,"InsID":12197},{"AutName":"Rouzé","Firstname":"Pierre","Initials":"P.","Affiliation":"Department of Plant Biotechnology and Bioinformatics, Ghent University","Discriminator":null,"CorporateFlag":0,"BEntID":249387,"AutID":181494,"OrderNr":3,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":"Universiteit Gent; Faculteit Wetenschappen; Vakgroep Plantenbiotechnologie en Bio-informatica","ORCID":null,"PersID":33010,"InsID":12197}],"mapdetails":null,"datasets":null,"monographs":null,"monparts":null,"serparts":null,"BEntOpen":null,"BEntPrivate":null,"availability":[{"BInstID":292327,"LibID":36,"BRefID":257378,"EmbargoDate":null,"FullEmbargoDate":null,"PhysMedID":16,"hasOCRd":1,"ShelfLocCode":"292327","RFID":null,"PaidValue":null,"Medium":"Server","Description":"VLIZ Open Access","Acronym":"VLIZ","Library":"Vlaams Instituut voor de Zee","DutchTerm":"Open access","URL":null,"ClassifID":53,"Classification":"Open access","ReqLink":null,"ClassifTypID":1,"URLLocation":"https://www.vliz.be/imisdocs/publications/","SubDir":null,"InternalReq":0,"LoggedInReq":0,"Disclaimer":null,"DutchDisclaimer":null,"FileFormat":".pdf","FileDescr":"pdf","InsPub":1,"InsID":36,"FileFormID":6,"LendableFlag":1,"PublicFlag":1,"orderLib":"A","Notes":null,"AccConID":null,"AccessConstraint":null,"LicURL":null}],"litstyles":null,"thespers":null,"arch2discl":null,"SERpubls":[{"PublName":"Oxford University Press","City":"Oxford"}],"MONpubls":null,"pictures":[],"thestermsPath":null,"thestermsASFA":null,"taxtermsASFA":[{"TaxTerm":"Mamiellophyceae"},{"TaxTerm":"Micromonas"}],"geotermsASFA":null,"collections":[{"Collection":"OMA - Open Marien Archief","ShortName":"OMA"}],"conf":null,"proj":null,"Physdatasets":null,"spcols":{"222":{"SpName":"BMB - Belgische Mariene Bibliografie","SpColID":222,"ParSpColID":null,"TopParID":null,"ShortName":"BMB","URLLocation":null,"LibID":36,"OpenRepoFlag":null,"SpTypID":null,"TopParIDNotWebsite":null,"SpColPath":"BMB"},"221":{"SpName":"OMA - Open Marien Archief","SpColID":221,"ParSpColID":null,"TopParID":null,"ShortName":"OMA","URLLocation":null,"LibID":36,"OpenRepoFlag":1,"SpTypID":null,"TopParIDNotWebsite":null,"SpColPath":"OMA"}},"doi":null,"publs":null,"serparttypes":null,"monauthors":null,"MParts":null,"SParts":null,"hLibs":null,"langs":[{"BEntID":249387,"AbstractFlag":0,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"},{"BEntID":249387,"AbstractFlag":1,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"}],"urls":[{"URL":"https://dx.doi.org/10.1093/gbe/evt189","externalID":"10.1093/gbe/evt189","URLTypeCode":"DOI","URLID":46699,"URLTypID":13,"URLType":"DOI","URLPrefix":"http://dx.doi.org/"}],"thesterms":null,"taxterms":[{"TaxTerm":"Mamiellophyceae","AphiaID":493835,"TaxtID":42689},{"TaxTerm":"Micromonas","AphiaID":134533,"TaxtID":42705}],"geoterms":null,"othterms":null,"asfacodes":null,"asfa2codes":null,"thestermsFRIS":null,"taxtermsFRIS":[{"TaxTerm":"Mamiellophyceae","DutchTerm":null,"AphiaID":493835,"TaxtID":42689},{"TaxTerm":"Micromonas","DutchTerm":null,"AphiaID":134533,"TaxtID":42705}],"geotermsFRIS":null,"othtermsFRIS":null,"resmessage":"","complete":1,"sessions":{"newSesName":"Lyssens, Liesbeth, L.","newSesDate":{"date":"2016-05-29 23:17:56.373000","timezone_type":3,"timezone":"Europe/Brussels"},"updSesName":"Haspeslagh, Jan, J.","updSesDate":{"date":"2016-06-21 11:51:14.827000","timezone_type":3,"timezone":"Europe/Brussels"}}}