{"refrec":{"BRefID":2668,"RR":"<b>Campbell, R.; Adams, A.; Tatner, M.F.; Chair, M.; Sorgeloos, P.</b> (1993). Uptake of <i>Vibrio anguillarum</i> vaccine by <i>Artemia salina</i> as a potential oral delivery system to fish fry. <i>Fish Shellfish Immunol. 3(6)</i>: 451-459. <a href=\"https://dx.doi.org/10.1006/fsim.1993.1044\" target=\"_blank\">https://dx.doi.org/10.1006/fsim.1993.1044</a>","BEntID":2668,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":1,"RefStringPartII":". <i>Fish Shellfish Immunol. 3(6)</i>: 451-459. <a href=\"https://dx.doi.org/10.1006/fsim.1993.1044\" target=\"_blank\">https://dx.doi.org/10.1006/fsim.1993.1044</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Campbell, R.; Adams, A.; Tatner, M.F.; Chair, M.; Sorgeloos, P.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Campbell, R. <i>et al.</i>","Englishabstract":"An ELISA to detect <i>Vibrio anguillarum</i> antigen in <i>Artemia salina</i> was developed. This assay was then used to determine the time course of antigen uptake by <i>Artemia</i> during incubations with <i>Vibrio</i> vaccine with a view to using <i>Artemia</i> as a vaccine carrier for oral vaccination of fish fry. The rate of uptake of vaccine by <i>Artemia</i> was shown to be concentration dependent. At a dose of 1.5x10<sup>7</sup> cfu ml<sup>-1</sup>, 1 mg wet weight of <i>Artemia</i> took up 1x10<sup>5</sup> cfu within 30min and reached maximum of 6x10<sup>6</sup> cfu after 60min. Thus each <i>Artemia</i> appears to have taken up approximately 1.2x10<sup>5</sup> cfu. Comparison of vaccine formulations indicated that uptake was consistently higher with formalised than with heat-treated vaccine.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Uptake of <i>Vibrio anguillarum</i> vaccine by <i>Artemia salina</i> as a potential oral delivery system to fish fry","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-06-06 01:31:51.586726","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":null,"Notes":null,"AnaPub":1993,"MonPub":null,"DateUpdate":"2003-01-07","DateCreate":"2000-08-24","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:A1993MJ15200005","VABBcode":null,"OpenAcc":0,"DOI":"10.1006/fsim.1993.1044"},"refs":null,"anarec":{"AnaID":2668,"PubliDate":1993,"Pagination":"451-459","XtraPublOfAnaID":null,"ISBN":null,"Volume":"3","Issue":"6","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":45027,"SerRR":"Fish & Shellfish Immunology. 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