{"refrec":{"BRefID":280773,"RR":"<b>Rolland, J.L.; Abdelouahab, M.; Dupont, J.; Lefevre, F.; Bachere, E.; Romestand, B.</b> (2010). Stylicins, a new family of antimicrobial peptides from the Pacific blue shrimp <i>Litopenaeus stylirostris</i>. <i>Molecular Immunology 47(6)</i>: 1269-1277. <a href=\"https://dx.doi.org/10.1016/j.molimm.2009.12.007\" target=\"_blank\">https://dx.doi.org/10.1016/j.molimm.2009.12.007</a>","BEntID":272792,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":0,"RefStringPartII":". <i>Molecular Immunology 47(6)</i>: 1269-1277. <a href=\"https://dx.doi.org/10.1016/j.molimm.2009.12.007\" target=\"_blank\">https://dx.doi.org/10.1016/j.molimm.2009.12.007</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Rolland, J.L.; Abdelouahab, M.; Dupont, J.; Lefevre, F.; Bachere, E.; Romestand, B.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Rolland, J.L. <i>et al.</i>","Englishabstract":"The present study reports the characterization of Ls-Stylicin1, a novel antimicrobial peptide from the penaeid shrimp, <i>Litopenaeus stylirostris</i>. The predicted mature peptide of 82 residues is negatively charged (theoretical p<i>I</i> = 5.0) and characterized by a proline-rich N-terminal region and a C-terminal region containing 13 cysteine residues. The recombinant Ls-Stylicin1 has been isolated in both monomeric and dimeric forms. Both display strong antifungal activity against <i>Fusarium oxysporum</i> (1.25 μM < MIC < 2.5 μM), a pathogenic fungus of shrimp, but lower antimicrobial activity against Gram (−) bacteria, <i>Vibrio</i> sp. (40 μM < MIC < 80 μM). However, rLs-Stylicin1 is able to agglutinate <i>Vibrio penaeicidae in vitro</i> in agreement with its potent LPS-binding activity on immobilized LPS of <i>V. penaeicidae</i> (dissociation constant (<i>K</i><sub>d</sub>) of 9.6 × 10<sup>−8</sup> M). This molecule with no evident homology to other hitherto described antimicrobial peptides but identified herein several species of penaeid shrimp is thought to be the first member of a shrimp antimicrobial peptide family, which we termed stylicins.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Stylicins, a new family of antimicrobial peptides from the Pacific blue shrimp <i>Litopenaeus stylirostris</i>","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2024-12-10 01:33:17.368041","timezone_type":1,"timezone":"+01:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"Ls-Stylicin 1; Peptide; Shrimp; Antifungal; Agglutination; Vibrio","OtherDescriptors":null,"Notes":null,"AnaPub":2010,"MonPub":null,"DateUpdate":"2022-07-13","DateCreate":"2016-10-09","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000276300600012","VABBcode":null,"OpenAcc":0,"DOI":"10.1016/j.molimm.2009.12.007"},"refs":null,"anarec":{"AnaID":280773,"PubliDate":2010,"Pagination":"1269-1277","XtraPublOfAnaID":null,"ISBN":null,"Volume":"47","Issue":"6","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":274935,"SerRR":"Molecular Immunology. 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