{"refrec":{"BRefID":285232,"RR":"<b>Schaeck, M.; Reyes-López, F.E.; Vallejos-Vidal, E.; Van Cleemput, J.; Duchateau, L.; Van Den Broeck, W.; Tort, L.; Decostere, A.</b> (2017). Cellular and transcriptomic response to treatment with the probiotic candidate <i>Vibrio lentus</i> in gnotobiotic sea bass (<i>Dicentrarchus labrax</i>) larvae. <i>Fish Shellfish Immunol. 63</i>: 147-156. <a href=\"https://dx.doi.org/10.1016/j.fsi.2017.01.028\" target=\"_blank\">https://dx.doi.org/10.1016/j.fsi.2017.01.028</a>","BEntID":277257,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":1,"RefStringPartII":". <i>Fish Shellfish Immunol. 63</i>: 147-156. <a href=\"https://dx.doi.org/10.1016/j.fsi.2017.01.028\" target=\"_blank\">https://dx.doi.org/10.1016/j.fsi.2017.01.028</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Schaeck, M.; Reyes-López, F.E.; Vallejos-Vidal, E.; Van Cleemput, J.; Duchateau, L.; Van Den Broeck, W.; Tort, L.; Decostere, A.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Schaeck, M. <i>et al.</i>","Englishabstract":"The present study aimed at evaluating the cellular and transcriptomic responses induced by the probiotic candidate <i>Vibrio lentus</i> with gnotobiotic European sea bass <i>(Dicentrarchus labrax,</i> Linnaeus 1785) larvae. For this, a histomorphological analysis was performed using the terminal deoxynucleotidyltransferase-mediated dUTP nick end labeling (TUNEL) and the anti-proliferating cell nuclear antigen (PCNA) assay. In addition, a global transcriptomic approach was adopted to study the whole body mRNA changes upon administration of <i>V. lentus</i> by microarrays with the custom Agilent sea bass oligonucleotide-microarray v2.0 (4 × 44 K). Following <i>V. lentus</i> administration, the apoptotic and cell proliferative indexes did not show significant differences between treatments for hindgut nor for midgut. However, <i>V. lentus</i> treatment did significantly modify the gene expression related not only to cell proliferation and cell death, but also to cell adhesion, reactive oxygen species metabolism, iron transport, and immune response.Our data represent the first global analysis of the effects of the probiotic candidate <i>V. lentus</i> on the gene expression profile in gnotobiotic European sea bass, and as such, provides a first delineation of the mechanisms by which this agent interacts with its host and exerts its beneficial effects.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Cellular and transcriptomic response to treatment with the probiotic candidate <i>Vibrio lentus</i> in gnotobiotic sea bass (<i>Dicentrarchus labrax</i>) larvae","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-04-19 01:31:50.031068","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"Microarrays; Vibrio; Sea bass; Histology; Probiotics; Immune response","OtherDescriptors":null,"Notes":null,"AnaPub":2017,"MonPub":null,"DateUpdate":"2019-07-15","DateCreate":"2017-05-16","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000398870700014","VABBcode":null,"OpenAcc":0,"DOI":"10.1016/j.fsi.2017.01.028"},"refs":null,"anarec":{"AnaID":285232,"PubliDate":2017,"Pagination":"147-156","XtraPublOfAnaID":null,"ISBN":null,"Volume":"63","Issue":null,"BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":45027,"SerRR":"Fish & Shellfish Immunology. Academic Press: London; New York.  ISSN 1050-4648; e-ISSN 1095-9947","StandardTitleSer":"Fish & Shellfish Immunology","ISSN":"1050-4648","AbbrevSer":"Fish Shellfish Immunol.","StandardTitleMon":null,"StartPage":147,"Pages":10,"ToPubliDate":null,"BRefBibLvlCode":"S","SerNotes":null},"monrec":null,"serrec":null,"relations":null,"relationsRev":null,"addrec":null,"othpubs":null,"ownerships":null,"authors":[{"AutName":"Schaeck","Firstname":"Marlien","Initials":"M.","Affiliation":"Department of Morphology, Faculty of Veterinary Medicine, Ghent University","Discriminator":null,"CorporateFlag":0,"BEntID":277257,"AutID":219172,"OrderNr":1,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":"Universiteit Gent; Faculteit Diergeneeskunde; Vakgroep Morfologie","ORCID":null,"PersID":26889,"InsID":11211},{"AutName":"Reyes-López","Firstname":"Felipe","Initials":"F.E.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":277257,"AutID":255044,"OrderNr":2,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Vallejos-Vidal","Firstname":"Eva","Initials":"E.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":277257,"AutID":255045,"OrderNr":3,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Van Cleemput","Firstname":"Jolien","Initials":"J.","Affiliation":"Department of Virology, Faculty of Veterinary Medicine, Ghent University","Discriminator":null,"CorporateFlag":0,"BEntID":277257,"AutID":255046,"OrderNr":4,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":"Universiteit Gent; Faculteit Diergeneeskunde; Vakgroep Virologie, Parasitologie en Immunologie; Laboratory of Virology","ORCID":null,"PersID":34598,"InsID":13137},{"AutName":"Duchateau","Firstname":"Luc","Initials":"L.","Affiliation":"Department of Comparative Physiology and Biometry, Faculty of Veterinary Medicine, Ghent University","Discriminator":null,"CorporateFlag":0,"BEntID":277257,"AutID":194196,"OrderNr":5,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":"Universiteit Gent; Faculteit Diergeneeskunde; Vakgroep Vergelijkende Fysiologie en Biometrie","ORCID":null,"PersID":31505,"InsID":12053},{"AutName":"Van Den Broeck","Firstname":"Wim","Initials":"W.","Affiliation":"Department of Morphology, Faculty of Veterinary Medicine, Ghent University","Discriminator":null,"CorporateFlag":0,"BEntID":277257,"AutID":145683,"OrderNr":6,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":"Universiteit Gent; Faculteit Diergeneeskunde; Vakgroep Morfologie","ORCID":"0000-0001-6683-5658","PersID":23230,"InsID":11211},{"AutName":"Tort","Firstname":"Lluis","Initials":"L.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":277257,"AutID":255049,"OrderNr":7,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Decostere","Firstname":"Annemie","Initials":"A.","Affiliation":"Department of Pathology, Bacteriology, and Avian Diseases, Faculty of Veterinary Medicine, Ghent University","Discriminator":null,"CorporateFlag":0,"BEntID":277257,"AutID":155634,"OrderNr":8,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":"Universiteit Gent; Faculteit Diergeneeskunde; Vakgroep Pathologie, Bacteriologie en Pluimveeziekten","ORCID":null,"PersID":26099,"InsID":11209}],"mapdetails":null,"datasets":null,"monographs":null,"monparts":null,"serparts":null,"BEntOpen":null,"BEntPrivate":null,"availability":[{"BInstID":333155,"LibID":36,"BRefID":285232,"EmbargoDate":null,"FullEmbargoDate":null,"PhysMedID":16,"hasOCRd":null,"ShelfLocCode":"333155","RFID":null,"PaidValue":null,"Medium":"Server","Description":"Interne VLIZ documenten","Acronym":"VLIZ","Library":"Vlaams Instituut voor de Zee","DutchTerm":"Non-open access","URL":null,"ClassifID":228,"Classification":"Non-open access","ReqLink":1,"ClassifTypID":3,"URLLocation":"https://www.vliz.be/imisdocs/publications/","SubDir":1,"InternalReq":1,"LoggedInReq":1,"Disclaimer":"Disclaimer_VLIZ_Intern","DutchDisclaimer":"<p>Deze publicatie is enkel beschikbaar voor persoonlijk gebruik binnen de Innovocean site <br />en mag op geen enkele manier verder worden verspreid.</p>","FileFormat":".pdf","FileDescr":"pdf","InsPub":1,"InsID":36,"FileFormID":6,"LendableFlag":1,"PublicFlag":1,"orderLib":"A","Notes":null,"AccConID":null,"AccessConstraint":null,"LicURL":null}],"litstyles":null,"thespers":null,"arch2discl":null,"SERpubls":[{"PublName":"Academic Press","City":"London; New York"}],"MONpubls":null,"pictures":[],"thestermsPath":null,"thestermsASFA":null,"taxtermsASFA":[{"TaxTerm":"Dicentrarchus labrax"},{"TaxTerm":"Vibrio"}],"geotermsASFA":null,"collections":null,"conf":null,"proj":null,"Physdatasets":null,"spcols":{"222":{"SpName":"BMB - Belgische Mariene Bibliografie","SpColID":222,"ParSpColID":null,"TopParID":null,"ShortName":"BMB","URLLocation":null,"LibID":36,"OpenRepoFlag":null,"SpTypID":null,"TopParIDNotWebsite":null,"SpColPath":"BMB"}},"doi":null,"publs":null,"serparttypes":null,"monauthors":null,"MParts":null,"SParts":null,"hLibs":null,"langs":[{"BEntID":277257,"AbstractFlag":0,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"},{"BEntID":277257,"AbstractFlag":1,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"}],"urls":[{"URL":"https://dx.doi.org/10.1016/j.fsi.2017.01.028","externalID":"10.1016/j.fsi.2017.01.028","URLTypeCode":"DOI","URLID":54966,"URLTypID":13,"URLType":"DOI","URLPrefix":"http://dx.doi.org/"}],"thesterms":null,"taxterms":[{"TaxTerm":"Dicentrarchus labrax [Bass]","AphiaID":126975,"TaxtID":23095},{"TaxTerm":"Vibrio","AphiaID":480248,"TaxtID":22617}],"geoterms":null,"othterms":null,"asfacodes":null,"asfa2codes":null,"thestermsFRIS":null,"taxtermsFRIS":[{"TaxTerm":"Dicentrarchus labrax","DutchTerm":"Zeebaars","AphiaID":126975,"TaxtID":23095},{"TaxTerm":"Vibrio","DutchTerm":null,"AphiaID":480248,"TaxtID":22617}],"geotermsFRIS":null,"othtermsFRIS":null,"resmessage":"","complete":1,"sessions":{"newSesName":"Lyssens, Liesbeth, L.","newSesDate":{"date":"2017-05-16 19:42:31.320000","timezone_type":3,"timezone":"Europe/Brussels"},"updSesName":"Bouchti, Zohra, Z.","updSesDate":{"date":"2019-07-15 09:04:03.807000","timezone_type":3,"timezone":"Europe/Brussels"}}}