{"refrec":{"BRefID":286426,"RR":"<b>Van Malderen, S.J.M.; Laforce, B.; Van Acker, T.; Nys, C.; De Rijcke, M.; de Rycke, R.; De Bruyne, M.; Boone, M.N.; De Schamphelaere, K.; Borovinskaya, O.; De Samber, B.; Vincze, L.; Vanhaecke, F.</b> (2017). Three-dimensional reconstruction of the tissue-specific multielemental distribution within Ceriodaphnia dubiavia multimodal registration using laser ablation ICP-mass spectrometry and X-ray spectroscopic techniques. <i>Anal. Chem. 89(7)</i>: 4161-4168. <a href=\"https://dx.doi.org/10.1021/acs.analchem.7b00111\" target=\"_blank\">https://dx.doi.org/10.1021/acs.analchem.7b00111</a>","BEntID":278450,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":1,"RefStringPartII":". <i>Anal. Chem. 89(7)</i>: 4161-4168. <a href=\"https://dx.doi.org/10.1021/acs.analchem.7b00111\" target=\"_blank\">https://dx.doi.org/10.1021/acs.analchem.7b00111</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":0,"FreshFlag":1,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Van Malderen, S.J.M.; Laforce, B.; Van Acker, T.; Nys, C.; De Rijcke, M.; de Rycke, R.; De Bruyne, M.; Boone, M.N.; De Schamphelaere, K.; Borovinskaya, O.; De Samber, B.; Vincze, L.; Vanhaecke, F.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Van Malderen, S.J.M. <i>et al.</i>","Englishabstract":"In this work, the three-dimensional elemental, distribution profile within the freshwater crustacean Ceriodaphnia dubia was constructed at a spatial resolution down to S mu m via a data, fusion approach employing state-of-the-art laser ablation inductively coupled plasma-time-of-flight mass spectrometry (LAICP-TOFMS) and laboratory-based absorption microcomputed tomography (mu-CT). C. dubia was exposed to elevated Cu, Ni, and Zn concentrations, chemically fixed, dehydrated, stained, and embedded, prior to mu-CT analysis. Subsequently, the sample was cut into 5 pm thin sections that were subjected to LA-ICPTOFMS imaging. Multimodal image registration was performed to spatially align the 2D LA-ICP-TOFMS images relative to the Corresponding slices of the 3D mu-CT reconstruction. Mass channels corresponding to the isotopes of a single element were merged to improve the signal-to-noise ratios within the elemental images. In order to aid the visual interpretation of the data, LA-ICP-TOEMS data wete projected onto the mu-CT voxels representing tissue. Additionally, the image resolution and elemental sensitivity were compared to those obtained with synchrotron radiation based 3D confocal mu-X-ray fluorescence imaging upon a chemically fixed and air-dried C. dubia specimen.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Three-dimensional reconstruction of the tissue-specific multielemental distribution within Ceriodaphnia dubiavia multimodal registration using laser ablation ICP-mass spectrometry and X-ray spectroscopic techniques","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-04-17 01:32:13.898239","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":null,"Notes":null,"AnaPub":2017,"MonPub":null,"DateUpdate":"2018-12-10","DateCreate":"2017-06-26","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000398645300050","VABBcode":null,"OpenAcc":0,"DOI":"10.1021/acs.analchem.7b00111"},"refs":null,"anarec":{"AnaID":286426,"PubliDate":2017,"Pagination":"4161-4168","XtraPublOfAnaID":null,"ISBN":null,"Volume":"89","Issue":"7","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":42100,"SerRR":"Analytical chemistry. 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