{"refrec":{"BRefID":287849,"RR":"<b>Milinkovitch, T.; Bustamante, P.; Huet, V.; Reigner, A.; Churlaud, C.; Thomas-Guyon, H.</b> (2015). <i>In situ</i> evaluation of oxidative stress and immunological parameters as ecotoxicological biomarkers in a novel sentinel species (<i>Mimachlamys varia</i>). <i>Aquat. Toxicol. 161</i>: 170-175. <a href=\"https://dx.doi.org/10.1016/j.aquatox.2015.02.003\" target=\"_blank\">https://dx.doi.org/10.1016/j.aquatox.2015.02.003</a>","BEntID":279874,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":null,"RefStringPartII":". <i>Aquat. Toxicol. 161</i>: 170-175. <a href=\"https://dx.doi.org/10.1016/j.aquatox.2015.02.003\" target=\"_blank\">https://dx.doi.org/10.1016/j.aquatox.2015.02.003</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":0,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Milinkovitch, T.; Bustamante, P.; Huet, V.; Reigner, A.; Churlaud, C.; Thomas-Guyon, H.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Milinkovitch, T. <i>et al.</i>","Englishabstract":"Although the variegated scallop <i>Mimachlamys varia</i> seems to be a suitable sentinel species for contaminant monitoring, no study has identified biomarkers in this species. In order to fill this gap, this study conducted an in situ biomarker approach. <i>M. varia</i> were collected in contaminated and uncontaminated areas and responsiveness of oxidative stress and immunological biomarkers was evaluated in the digestive gland. In parallel, 14 trace element concentrations were evaluated in the same organ. Superoxide dismutase activity and malondialdehyde content responded efficiently to <i>in situ</i> contamination when a certain degree of contamination was reached. Laccase-type phenoloxidase showed a high sensitivity but saturation of the response was highlighted for the highest contaminations. Additionally, correlations were found between biomarkers and trace element concentrations. Taken together, results showed that biomarker approach conducted in the digestive gland of <i>M. varia</i> represents a sensitive analytical tool to highlight ecotoxicological issues in coastal marine ecosystems.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"<i>In situ</i> evaluation of oxidative stress and immunological parameters as ecotoxicological biomarkers in a novel sentinel species (<i>Mimachlamys varia</i>)","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-06-10 01:32:08.993224","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"Mimachlamys varia, Biomarkers, Trace elements, Oxidative stress, Phenoloxidase","OtherDescriptors":null,"Notes":null,"AnaPub":2015,"MonPub":null,"DateUpdate":"2018-02-13","DateCreate":"2017-08-10","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000352177500019","VABBcode":null,"OpenAcc":0,"DOI":"10.1016/j.aquatox.2015.02.003"},"refs":null,"anarec":{"AnaID":287849,"PubliDate":2015,"Pagination":"170-175","XtraPublOfAnaID":null,"ISBN":null,"Volume":"161","Issue":null,"BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":42203,"SerRR":"Aquatic Toxicology. 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