Document of bibliographic reference 288513

BibliographicReference record

Type

Bibliographic resource

Type of document

Journal article

BibLvlCode

AS

Title

Toxicity against Artemia salina of the zoanthid Palythoa caribaeorum (Cnidaria: Anthozoa) used in folk medicine on the coast of Pernambuco, Brazil

Abstract

Palythoa caribaeorum is a zoanthid whose mucus is traditionally used by fishermen communities on the southern coast of the state of Pernambuco as an anesthetic and anti-inflammatory agent, as well as for the treatment of topical wounds. In order to evaluate a possible toxicity, hexane and ethanol extracts of the zoanthid obtained from the beaches of Piedade (PCP-H; PCP-E), Guadalupe (PCG-H; PCG-E), and Suape (PCS-H; PCS-E) were tested against Artemia salina larvae. Among the six extracts tested, PCP-H, PCP-E, PCS-H, and PCS-E showed low toxicity, with LC50 values above 250µg/mL. On the other hand, PCG-H (80 < LC50 < 250µg/mL) was categorized as moderately toxic, while PCG-E (LC50 < 80µg/mL) was considered as highly toxic, with its degree of toxicity close to that of the standard drug cyclophosphamide (LC50 = 19.7µg/mL). The results indicate the presence of toxic compounds in the zoanthid obtained from Guadalupe and they suggest caution in the use of P. caribaeorum as a folk remedy. The variations found in the extracts of the tested Pernambucan populations of P. caribaeorum corroborate previous reports that the toxic action of this zoanthid is not inherent to the species, but it is influenced by environmental conditions and associated organisms.

Bibliographic citation

de Andrade Melo, L.F.; da Camara, C.A.G.; da Silva Selva de Oliveira, L.L.D.; de Albuquerque Modesto, J.C.; Pérez, C.D. (2012). Toxicity against Artemia salina of the zoanthid Palythoa caribaeorum (Cnidaria: Anthozoa) used in folk medicine on the coast of Pernambuco, Brazil. Biotemas 25(3): 145-151. https://dx.doi.org/10.5007/2175-7925.2012v25n3p145

Topic

Marine

Is peer reviewed

true

Access rights

open access

Is accessible for free

true