{"refrec":{"BRefID":288592,"RR":"<b>Kuan, C.S.; Yew, S.M.; Chan, C.L.; Toh, Y.F.; Lee, K.W.; Cheong, W.H.; Yee, W.Y.; Hoh, C.-C.; Yap, S.-J.; Ng, K.P.</b> (2016). DemaDb: an integrated dematiaceous fungal genomes database. <i>Database 2016</i>: baw008. <a href=\"https://dx.doi.org/10.1093/database/baw008\" target=\"_blank\">https://dx.doi.org/10.1093/database/baw008</a>","BEntID":280625,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":null,"RefStringPartII":". <i>Database 2016</i>: baw008. <a href=\"https://dx.doi.org/10.1093/database/baw008\" target=\"_blank\">https://dx.doi.org/10.1093/database/baw008</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":0,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Kuan, C.S.; Yew, S.M.; Chan, C.L.; Toh, Y.F.; Lee, K.W.; Cheong, W.H.; Yee, W.Y.; Hoh, C.-C.; Yap, S.-J.; Ng, K.P.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Kuan, C.S. <i>et al.</i>","Englishabstract":"Many species of dematiaceous fungi are associated with allergic reactions and potentially fatal diseases in human, especially in tropical climates. Over the past 10 years, we have isolated more than 400 dematiaceous fungi from various clinical samples. In this study, DemaDb, an integrated database was designed to support the integration and analysis of dematiaceous fungal genomes. A total of 92 072 putative genes and 6527 pathways that identified in eight dematiaceous fungi ( <i>Bipolaris papendorfii</i> UM 226, <i>Daldinia eschscholtzii</i> UM 1400, <i>D. eschscholtzii</i> UM 1020, <i>Pyrenochaeta unguis-hominis</I> UM 256, <i>Ochroconis mirabilis</i> UM 578, <i>Cladosporium sphaerospermum</i> UM 843, <i>Herpotrichiellaceae</i> sp. UM 238 and <i>Pleosporales</i> sp. UM 1110) were deposited in DemaDb. DemaDb includes functional annotations for all predicted gene models in all genomes, such as Gene Ontology, EuKaryotic Orthologous Groups, Kyoto Encyclopedia of Genes and Genomes (KEGG), Pfam and InterProScan. All predicted protein models were further functionally annotated to Carbohydrate-Active enzymes, peptidases, secondary metabolites and virulence factors. DemaDb Genome Browser enables users to browse and visualize entire genomes with annotation data including gene prediction, structure, orientation and custom feature tracks. The Pathway Browser based on the KEGG pathway database allows users to look into molecular interaction and reaction networks for all KEGG annotated genes. The availability of downloadable files containing assembly, nucleic acid, as well as protein data allows the direct retrieval for further downstream works. DemaDb is a useful resource for fungal research community especially those involved in genome-scale analysis, functional genomics, genetics and disease studies of dematiaceous fungi.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"DemaDb: an integrated dematiaceous fungal genomes database","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-06-15 01:33:00.504321","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":null,"Notes":null,"AnaPub":2016,"MonPub":null,"DateUpdate":"2018-02-13","DateCreate":"2017-08-23","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000374089700002","VABBcode":null,"OpenAcc":1,"DOI":"10.1093/database/baw008"},"refs":null,"anarec":{"AnaID":288592,"PubliDate":2016,"Pagination":"baw008","XtraPublOfAnaID":null,"ISBN":null,"Volume":"2016","Issue":null,"BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":244393,"SerRR":"Database: The Journal of Biological Databases and Curation. 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