{"refrec":{"BRefID":291609,"RR":"<b>Thomas, S.A.L.; von Salm, J.L.; Clark, S.; Ferlita, S.; Nemani, P.; Azhari, A.; Rice, C.A.; Wilson, N.G.; Kyle, D.E.; Baker, B.J.</b> (2018). Keikipukalides, furanocembrane diterpenes from the Antarctic deep sea octocoral <i>Plumarella delicatissima</i>. <i>J. Nat. Prod. 81(1)</i>: 117-123. <a href=\"https://dx.doi.org/10.1021/acs.jnatprod.7b00732\" target=\"_blank\">https://dx.doi.org/10.1021/acs.jnatprod.7b00732</a>","BEntID":283652,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":null,"RefStringPartII":". <i>J. Nat. Prod. 81(1)</i>: 117-123. <a href=\"https://dx.doi.org/10.1021/acs.jnatprod.7b00732\" target=\"_blank\">https://dx.doi.org/10.1021/acs.jnatprod.7b00732</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Thomas, S.A.L.; von Salm, J.L.; Clark, S.; Ferlita, S.; Nemani, P.; Azhari, A.; Rice, C.A.; Wilson, N.G.; Kyle, D.E.; Baker, B.J.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Thomas, S.A.L. <i>et al.</i>","Englishabstract":"During a 2013 cruise in the Southern Ocean we collected specimens of the octocoral <i>Plumarella delicatissima</i> between 800 and 950 m depth. Five new furanocembranoid diterpenes, keikipukalides A–E (1–5), the known diterpene pukalide aldehyde (6), and the known norditerpenoid ineleganolide (7) were isolated from the coral. These <i>Plumarella</i> terpenes lack mammalian cytotoxicity, while 2–7 display activity against <i>Leishmania donovani</i> between 1.9 and 12 μM. 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