Document of bibliographic reference 291609
BibliographicReference record
- Type
- Bibliographic resource
- Type of document
- Journal article
- BibLvlCode
- AS
- Title
- Keikipukalides, furanocembrane diterpenes from the Antarctic deep sea octocoral Plumarella delicatissima
- Abstract
- During a 2013 cruise in the Southern Ocean we collected specimens of the octocoral Plumarella delicatissima between 800 and 950 m depth. Five new furanocembranoid diterpenes, keikipukalides A–E (1–5), the known diterpene pukalide aldehyde (6), and the known norditerpenoid ineleganolide (7) were isolated from the coral. These Plumarella terpenes lack mammalian cytotoxicity, while 2–7 display activity against Leishmania donovani between 1.9 and 12 μM. Structure elucidation was facilitated by one- and two-dimensional NMR spectroscopy and mass spectrometry, and keikipukalides A and E were confirmed by X-ray crystallography.
- WebOfScience code
- https://www.webofscience.com/wos/woscc/full-record/WOS:000423778900017
- Bibliographic citation
- Thomas, S.A.L.; von Salm, J.L.; Clark, S.; Ferlita, S.; Nemani, P.; Azhari, A.; Rice, C.A.; Wilson, N.G.; Kyle, D.E.; Baker, B.J. (2018). Keikipukalides, furanocembrane diterpenes from the Antarctic deep sea octocoral Plumarella delicatissima. J. Nat. Prod. 81(1): 117-123. https://dx.doi.org/10.1021/acs.jnatprod.7b00732
- Topic
- Marine
- Is peer reviewed
- true
- Access rights
- open access
- Is accessible for free
- true
Authors
- author
-
- Name
- Santana Thomas
- author
-
- Name
- Jacqueline von Salm
- author
-
- Name
- Shane Clark
- author
-
- Name
- Steve Ferlita
- author
-
- Name
- Prasanth Nemani
- author
-
- Name
- Ala Azhari
- author
-
- Name
- Christopher Rice
- author
-
- Name
- Nerida Wilson
- Identifier
- https://orcid.org/0000-0002-0784-0200
- author
-
- Name
- Dennis Kyle
- author
-
- Name
- Bill Baker