{"refrec":{"BRefID":292958,"RR":"<b>Fraga, J.; Rojas, L.; Sariego, I.; Fernández-Calienes, A.</b> (2012). Genetic characterization of three Cuban <i>Trichomonas vaginalis</i> virus. Phylogeny of <i>Totiviridae</i> family. <i>Infect. Genet. Evol. 12(1)</i>: 113-120. <a href=\"https://dx.doi.org/10.1016/j.meegid.2011.10.020\" target=\"_blank\">https://dx.doi.org/10.1016/j.meegid.2011.10.020</a>","BEntID":285012,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":1,"RefStringPartII":". <i>Infect. Genet. Evol. 12(1)</i>: 113-120. <a href=\"https://dx.doi.org/10.1016/j.meegid.2011.10.020\" target=\"_blank\">https://dx.doi.org/10.1016/j.meegid.2011.10.020</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":0,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Fraga, J.; Rojas, L.; Sariego, I.; Fernández-Calienes, A.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Fraga, J. <i>et al.</i>","Englishabstract":"<i>Trichomonas vaginalis</i> can be infected with double stranded RNA (dsRNA) viruses known as <i>T. vaginalis</i> virus (TVV). This viral infection may have important implications for trichomonal virulence and disease pathogenesis. In this study we identified and genetic characterized three strains of TVVs isolated from <i>T. vaginalis</i> in Cuba. The three new predicted sequences of capsid protein and RNA-dependent RNA polymerase amounted to the previously determined 20 TVV sequences and other 21 viruses of <i>Totiviridae</i> family were used for a phylogenetic analysis. Four distinct monophyletic clades are shown in a phylogenetic tree. One corresponds with TVVs, other with <i>Victorivirus</i>, <i>Leishmaniavirus</i> and <i>Eimeria brunetti</i> virus and, other with viruses of the genus <i>Totivirus</i> and the last with <i>Giardiavirus</i>. The <i>E. brunetti</i> virus is identified in the phylogenetic tree as independent taxon between <i>Leishmaniavirus</i> and <i>Victorivirus</i> isolates, most closely related to <i>Victorivirus</i>. TVV constitute a monophyletic cluster distinguishable from all other viruses in <i>Totiviridae</i> family. This result suggested that TVV may be grouped in a separated genus and not inside of <i>Giardiavirus</i>. TVVs appear to be more closely related to protozoan viruses in the genus <i>Leishmaniavirus</i> and to fungal viruses in the genus <i>Victorivirus</i> than to other protozoan and fungal viruses in <i>Giardiavirus</i> and <i>Totivirus</i>. Among TVVs, four main groups can be recognized within <i>Trichomonasvirus</i> cluster, which correspond with the previous species classification proposed. Further studies, with more TVV strains, especially TVV3 and 4 strains, are needed in order to determine the phylogenetic relationship among <i>Trichomonasvirus</i> genus and specifically if TVV2 and 3 each also constitute a well-delimited group.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Genetic characterization of three Cuban <i>Trichomonas vaginalis</i> virus. Phylogeny of <i>Totiviridae</i> family","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-06-15 01:33:02.957665","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"Trichomonas vaginalis; Trichomonas vaginalis virus; Trichomonasvirus; Phylogeny; Genome sequence","OtherDescriptors":null,"Notes":null,"AnaPub":2012,"MonPub":null,"DateUpdate":"2018-02-26","DateCreate":"2018-02-26","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000299599600014","VABBcode":null,"OpenAcc":0,"DOI":"10.1016/j.meegid.2011.10.020"},"refs":null,"anarec":{"AnaID":292958,"PubliDate":2012,"Pagination":"113-120","XtraPublOfAnaID":null,"ISBN":null,"Volume":"12","Issue":"1","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":292957,"SerRR":"Infection, Genetics and Evolution. Elsevier Science: Amsterdam.  ISSN 1567-1348; e-ISSN 1567-7257","StandardTitleSer":"Infection, Genetics and Evolution","ISSN":"1567-1348","AbbrevSer":"Infect. Genet. 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