{"refrec":{"BRefID":29366,"RR":"<b>Ortuño, J.; Esterban, M.A.; Meseguer, J.</b> (2002). Effects of four anaesthetics on the innate immune response of gilthead seabream (<i>Sparus aurata</i> L.). <i>Fish Shellfish Immunol. 12(1)</i>: 49-59. <a href=\"https://dx.doi.org/10.1006/fsim.2001.0353\" target=\"_blank\">https://dx.doi.org/10.1006/fsim.2001.0353</a>","BEntID":29366,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":1,"RefStringPartII":". <i>Fish Shellfish Immunol. 12(1)</i>: 49-59. <a href=\"https://dx.doi.org/10.1006/fsim.2001.0353\" target=\"_blank\">https://dx.doi.org/10.1006/fsim.2001.0353</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":1,"BrackishFlag":1,"TerrestrialFlag":0,"Authorstring":"Ortuño, J.; Esterban, M.A.; Meseguer, J.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Ortuño, J.; Esterban, M.A.; Meseguer, J.","Englishabstract":"Anaesthesia may depress the immune system in mammals, but there is no available information on this topic in fish. In the present work, four anaesthetics that are used in aquaculture, MS222 (0·19mM), benzocaine (0·21mM), 2-phenoxyethanol (1·6mM) and quinaldine sulphate (0·083mM), were tested in order to observe their effects on the gilthead seabream (<i>Sparus aurata</i> L.) innate immune system. The results showed that the four anaesthetics produced increased blood glucose levels after an hour. In addition, benzocaine and 2-phenoxyethanol depressed complement activity and phagocytosis, while MS222 and quinaldine sulphate did not. Some anaesthesia is a common practice in aquaculture, the data obtained should be taken into account to avoid possible immunodepression in farmed fish.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Effects of four anaesthetics on the innate immune response of gilthead seabream (<i>Sparus aurata</i> L.)","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-06-14 01:31:04.265228","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":"anaesthetics, MS222, benzocaine, 2-phenoxyethanol, quinaldine sulphate, innate immune response, gilthead seabream (<i>Sparus aurata</i> L.)","Notes":null,"AnaPub":2002,"MonPub":null,"DateUpdate":"2002-11-13","DateCreate":"2002-11-13","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000173477000004","VABBcode":null,"OpenAcc":0,"DOI":"10.1006/fsim.2001.0353"},"refs":null,"anarec":{"AnaID":29366,"PubliDate":2002,"Pagination":"49-59","XtraPublOfAnaID":null,"ISBN":null,"Volume":"12","Issue":"1","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":45027,"SerRR":"Fish & Shellfish Immunology. 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ISSN 1050-4648; e-ISSN 1095-9947","StandardTitleSer":"Fish & Shellfish Immunology","ISSN":"1050-4648","AbbrevSer":"Fish Shellfish Immunol.","StandardTitleMon":null,"StartPage":49,"Pages":11,"ToPubliDate":null,"BRefBibLvlCode":"S","SerNotes":null},"monrec":null,"serrec":null,"relations":null,"relationsRev":null,"addrec":{"Line1":"30071, Murcia","Email":"meseguer@fcu.um.es","Line2":null,"EnvName":"Spain"},"othpubs":null,"ownerships":null,"authors":[{"AutName":"Ortuño","Firstname":null,"Initials":"J.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":29366,"AutID":31981,"OrderNr":1,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Esterban","Firstname":null,"Initials":"M.A.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":29366,"AutID":31982,"OrderNr":2,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Meseguer","Firstname":null,"Initials":"J.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":29366,"AutID":31983,"OrderNr":3,"DegrID":null,"EditorFlag":0,"CorrespFlag":1,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null}],"mapdetails":null,"datasets":null,"monographs":null,"monparts":null,"serparts":null,"BEntOpen":null,"BEntPrivate":null,"availability":null,"litstyles":null,"thespers":null,"arch2discl":null,"SERpubls":[{"PublName":"Academic Press","City":"London; New York"}],"MONpubls":null,"pictures":[],"thestermsPath":[{"ThesaurusTerm":"Anaesthetics","ThestID":352,"Acronym":"ASFA","ThesTermPath":"Drugs > Anaesthetics"},{"ThesaurusTerm":"Benzocaine","ThestID":117940,"Acronym":"CAB","ThesTermPath":"Drugs > Neurotropic drugs > Anaesthetics > Local anaesthetics > Benzocaine"},{"ThesaurusTerm":"Immunity","ThestID":4247,"Acronym":"ASFA","ThesTermPath":"Properties > Biological properties > Immunity"}],"thestermsASFA":[{"ThesaurusTerm":"Anaesthetics"},{"ThesaurusTerm":"Benzocaine"},{"ThesaurusTerm":"Immunity"}],"taxtermsASFA":[{"TaxTerm":"Sparus aurata"}],"geotermsASFA":null,"collections":null,"conf":null,"proj":null,"Physdatasets":null,"spcols":null,"doi":null,"publs":null,"serparttypes":null,"monauthors":null,"MParts":null,"SParts":null,"hLibs":null,"langs":[{"BEntID":29366,"AbstractFlag":0,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"}],"urls":[{"URL":"https://dx.doi.org/10.1006/fsim.2001.0353","externalID":"10.1006/fsim.2001.0353","URLTypeCode":"DOI","URLID":109826,"URLTypID":13,"URLType":"DOI","URLPrefix":"http://dx.doi.org/"}],"thesterms":[{"ThesaurusTerm":"Anaesthetics","ThestID":352,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Benzocaine","ThestID":117940,"Acronym":"CAB","ThesTypID":4,"ThesType":"CAB Thesaurus"},{"ThesaurusTerm":"Immunity","ThestID":4247,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"}],"taxterms":[{"TaxTerm":"Sparus aurata [Gilthead]","AphiaID":151523,"TaxtID":23096}],"geoterms":null,"othterms":[{"OtherTerm":"2-phenoxyethanol","OthtID":9360},{"OtherTerm":"Gilthead seabream (<i>sparus aurata</i> l.)","OthtID":8093},{"OtherTerm":"Innate immune response","OthtID":11593},{"OtherTerm":"Ms222","OthtID":6462},{"OtherTerm":"Quinaldine sulphate","OthtID":11146}],"asfacodes":null,"asfa2codes":null,"thestermsFRIS":[{"ThesaurusTerm":"Anaesthetics","DutchTerm":null,"ThestID":352,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Benzocaine","DutchTerm":null,"ThestID":117940,"Acronym":"CAB","ThesTypID":4,"ThesType":"CAB Thesaurus"},{"ThesaurusTerm":"Immunity","DutchTerm":"Immuniteit","ThestID":4247,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"}],"taxtermsFRIS":[{"TaxTerm":"Sparus aurata","DutchTerm":"Goudbrasem","AphiaID":151523,"TaxtID":23096}],"geotermsFRIS":null,"othtermsFRIS":[{"OtherTerm":"2-phenoxyethanol","DutchTerm":null,"OthtID":9360},{"OtherTerm":"Gilthead seabream (<i>sparus aurata</i> l.)","DutchTerm":null,"OthtID":8093},{"OtherTerm":"Innate immune response","DutchTerm":null,"OthtID":11593},{"OtherTerm":"Ms222","DutchTerm":null,"OthtID":6462},{"OtherTerm":"Quinaldine sulphate","DutchTerm":null,"OthtID":11146}],"resmessage":"","complete":1,"sessions":{"newSesName":"Chisala, Chilekwa, C.","newSesDate":{"date":"2002-11-13 08:54:50.403000","timezone_type":3,"timezone":"Europe/Brussels"},"updSesName":"Chisala, Chilekwa, C.","updSesDate":{"date":"2002-11-13 08:54:50.403000","timezone_type":3,"timezone":"Europe/Brussels"}}}