{"refrec":{"BRefID":298615,"RR":"<b>Lee, S.-M.; Lee, Y.-R.; Choi, K.-S.; Cho, Y.-N.; Lee, H.A.; Hwang, D.Y.; Jung, Y.J.; Son, H.J.</b> (2015). Stalked sea squirt (<i>Styela clava</i>) tunic waste as a valuable bioresource: Cosmetic and antioxidant activities. <i>Process Biochemistry 50(11)</i>: 1977-1984. <a href=\"https://dx.doi.org/10.1016/j.procbio.2015.07.018\" target=\"_blank\">https://dx.doi.org/10.1016/j.procbio.2015.07.018</a>","BEntID":290721,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":1,"RefStringPartII":". <i>Process Biochemistry 50(11)</i>: 1977-1984. <a href=\"https://dx.doi.org/10.1016/j.procbio.2015.07.018\" target=\"_blank\">https://dx.doi.org/10.1016/j.procbio.2015.07.018</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":0,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Lee, S.-M.; Lee, Y.-R.; Choi, K.-S.; Cho, Y.-N.; Lee, H.A.; Hwang, D.Y.; Jung, Y.J.; Son, H.J.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Lee, S.-M. <i>et al.</i>","Englishabstract":"The aim of this study was to assess the skin aging related-enzyme inhibitory effects and antioxidant effects of different solvent extracts of the tunics of the solitary ascidian tunicate Styela clava, which are regarded as fishery waste. All extracts dose-dependently inhibited the enzyme activities of collagenase, elastase and hyaluronidase. The anticollagenase activities (IC<sub>50</sub>) of hot water (5.058 mg/ml) and n-butanol (5.760 mg/ml) extracts were comparable to that of ascorbic acid (3.838 mg/ml), but lower than that of EDTA (10.856 mg/ml). The antielastase activities (IC<sub>50</sub>) of ethanol (0.356 mg/ml), acetone (1.668 mg/ml), and n-butanol (2.040 mg/ml) extracts were much lower than that of ursolic acid (4.073 mg/ml), a representative elastase inhibitor, and the antihyaluronidase activities of ethyl acetate (0.210 mg/ml) and hexane (0.596 mg/ml) extracts were lower than that of ketoprofen, a well-known hyaluronidase inhibitor. Hot water extract scavenged ABTS radicals with an IC<sub>50</sub> value of 0.192 mg/ml, which was comparable to that of ascorbic acid (0.052 mg/ml). These results suggest that S. clava tunics (SCTs) are a potential candidate for wrinkle-care cosmetics and for the treatment of inflammation-related disorders. As far as we are aware, this is the first report to describe the potential antiaging activity of SCT.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Stalked sea squirt (<i>Styela clava</i>) tunic waste as a valuable bioresource: Cosmetic and antioxidant activities","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2024-12-10 01:33:17.368041","timezone_type":1,"timezone":"+01:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"Antioxidant; Anticollagenase; Antielastase; Antihyaluronidase; Styela clava tunic","OtherDescriptors":null,"Notes":null,"AnaPub":2015,"MonPub":null,"DateUpdate":"2018-07-17","DateCreate":"2018-07-17","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000365064800037","VABBcode":null,"OpenAcc":0,"DOI":"10.1016/j.procbio.2015.07.018"},"refs":null,"anarec":{"AnaID":298615,"PubliDate":2015,"Pagination":"1977-1984","XtraPublOfAnaID":null,"ISBN":null,"Volume":"50","Issue":"11","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":276788,"SerRR":"Process Biochemistry. 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