{"refrec":{"BRefID":307933,"RR":"<b>Elst, K.; Maesen, M.; Jacobs, G.; Bastiaens, L.; Voorspoels, S.; Servaes, K.</b> (2018). Supercritical CO<sub>2</sub> extraction of <i>Nannochloropsis</i> sp.: a lipidomic study on the influence of pretreatment on yield and composition. <i>Molecules 23(8)</i>: 1854. <a href=\"https://dx.doi.org/10.3390/molecules23081854\" target=\"_blank\">https://dx.doi.org/10.3390/molecules23081854</a>","BEntID":300259,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":1,"RefStringPartII":". <i>Molecules 23(8)</i>: 1854. <a href=\"https://dx.doi.org/10.3390/molecules23081854\" target=\"_blank\">https://dx.doi.org/10.3390/molecules23081854</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Elst, K.; Maesen, M.; Jacobs, G.; Bastiaens, L.; Voorspoels, S.; Servaes, K.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Elst, K. <i>et al.</i>","Englishabstract":"Algal lipids have gained wide interest in various applications ranging from biofuels to nutraceuticals. Given their complex nature composed of different lipid classes, a deep knowledge between extraction conditions and lipid characteristics is essential. In this paper, we investigated the influence of different pretreatments on lipid extraction with supercritical CO<sub>2</sub> by a lipidomic approach. Pretreatment was found to double the total extraction yield, thereby reaching 23.1 wt.% comparable to the 26.9 wt.% obtained with chloroform/methanol. An increase in acylglycerides was concurrently observed, together with a nearly doubling of free fatty acids indicative of partial hydrolysis. Moreover, an alteration in the distribution of glyco- and phospholipids was noted, especially promoting digalactosyldiglycerides and phosphatidylcholine as compared to monogalactosyldiglycerides and phosphatidylglycerol. At optimized conditions, supercritical CO<sub>2</sub> extraction provided a lipid extract richer in neutral lipids and poorer in phospholipids as compared to chloroform/methanol, though with a very similar fatty acid distribution within each lipid class.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Supercritical CO<sub>2</sub> extraction of <i>Nannochloropsis</i> sp.: a lipidomic study on the influence of pretreatment on yield and composition","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2024-12-10 01:33:17.368041","timezone_type":1,"timezone":"+01:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"Nannochloropsis sp.; supercritical CO2 extraction; microalgae;pretreatment; lipidomic; UHPLC-PDA-HR-MS; glycolipids; phospholipids;glycerides; mass transfer limitations","OtherDescriptors":null,"Notes":null,"AnaPub":2018,"MonPub":null,"DateUpdate":"2019-03-18","DateCreate":"2019-03-13","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000445295500019","VABBcode":null,"OpenAcc":1,"DOI":"10.3390/molecules23081854"},"refs":null,"anarec":{"AnaID":307933,"PubliDate":2018,"Pagination":"1854","XtraPublOfAnaID":null,"ISBN":null,"Volume":"23","Issue":"8","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":259137,"SerRR":"Molecules. 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