{"refrec":{"BRefID":309848,"RR":"<b>Tapper, A.R.; George Jr., A.L.</b> (2003). Heterologous expression of ion channels, <b><i>in</i></b>: Potter, N.T. <i>Neurogenetics: Methods and protocols. Methods in Molecular Biology,</i> 217: pp. 285-294. <a href=\"https://dx.doi.org/10.1385/1-59259-330-5:285\" target=\"_blank\">https://dx.doi.org/10.1385/1-59259-330-5:285</a>","BEntID":302176,"PublicFlag":1,"CheckedFlag":0,"wosflag":0,"vabbflag":0,"RefStringPartII":", <b><i>in</i></b>: Potter, N.T. <i>Neurogenetics: Methods and protocols. Methods in Molecular Biology,</i> 217: pp. 285-294. <a href=\"https://dx.doi.org/10.1385/1-59259-330-5:285\" target=\"_blank\">https://dx.doi.org/10.1385/1-59259-330-5:285</a>","DocTypID":17,"DocType":"Book chapters","MarineFlag":0,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Tapper, A.R.; George Jr., A.L.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Tapper, A.R.; George Jr., A.L.","Englishabstract":"The use of recombinant DNA technology to clone, sequence, and express ion channels and transporters has powered an enormous acceleration in the understanding of structure-function relationships in these important proteins. Given that most ion channels reside in tissues that are largely inaccessible to direct recording techniques and the general paucity of continuous cell lines expressing defined populations of functional molecules, studying native channels is often difficult and impractical. 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