{"refrec":{"BRefID":310095,"RR":"<b>Afifi, R.; Abdel-Nabi, I.M.; El-Shaikh, K.</b> (2016). Antibacterial activity from soft corals of the Red Sea, Saudi Arabia. <i>Journal of Taibah University for Science 10(6)</i>: 887-895. <a href=\"https://dx.doi.org/10.1016/j.jtusci.2016.03.006\" target=\"_blank\">https://dx.doi.org/10.1016/j.jtusci.2016.03.006</a>","BEntID":302426,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":0,"RefStringPartII":". <i>Journal of Taibah University for Science 10(6)</i>: 887-895. <a href=\"https://dx.doi.org/10.1016/j.jtusci.2016.03.006\" target=\"_blank\">https://dx.doi.org/10.1016/j.jtusci.2016.03.006</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Afifi, R.; Abdel-Nabi, I.M.; El-Shaikh, K.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Afifi, R. <i>et al.</i>","Englishabstract":"The present study aimed to screen for antibacterial activities in soft corals of the eastern Red Sea coast. Specimens of different species were surveyed, collected, preserved, extracted and assayed according to standard protocols. Bioactive materials were extracted using a dichloromethane/methanol mixture, and the activity was determined using the well diffusion and microdilution assay methods. All extracts demonstrated variable activity against marine bacteria previously isolated from the sea water (in situ near the soft corals). Among soft corals, <i>Sarcophyton</i> spp. and <i>Sinularia polydactyla</i> showed the highest activity (MIC = 30–50 μg/ml), while the crude extract of <i>Xenia</i> spp. showed the lowest activity (MIC = 200–250 μg/ml) against the isolated marine bacterial strains.Antibacterial activity was observed for five out of the seven soft coral extracts (72%) against two Gram-positive (<i>Staphylococcus aureus</i> and <i>Bacillus</i> spp.) bacterial pathogens, while none of the extracts inhibited Gram-negative (<i>Escherichia coli</i>) bacteria. The most potent (MIC = 40–75 μg/ml) crude extracts were obtained from <i>S. polydactyla</i> and <i>Sarcophyton</i> spp., while the crude extract of Xenia spp. was the least effective (MIC ≥ 200 μg/ml) against the tested Gram-positive bacteria. The results from the current study suggest that soft corals of the Red Sea (Yunbu, SA) are a potential source of novel antibiotics.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Antibacterial activity from soft corals of the Red Sea, Saudi Arabia","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2024-12-10 01:33:01.897972","timezone_type":1,"timezone":"+01:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":null,"Notes":null,"AnaPub":2016,"MonPub":null,"DateUpdate":"2019-04-02","DateCreate":"2019-04-02","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000396406400011","VABBcode":null,"OpenAcc":1,"DOI":"10.1016/j.jtusci.2016.03.006"},"refs":null,"anarec":{"AnaID":310095,"PubliDate":2016,"Pagination":"887-895","XtraPublOfAnaID":null,"ISBN":null,"Volume":"10","Issue":"6","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":273337,"SerRR":"Journal of Taibah University for Science. 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