{"refrec":{"BRefID":322668,"RR":"<b>Gutiérrez, J.; Maere, S.</b> (2014). Modeling the evolution of molecular systems from a mechanistic perspective. <i>Trends Plant Sci. 19(5)</i>: 292-303. <a href=\"https://dx.doi.org/10.1016/j.tplants.2014.03.004\" target=\"_blank\">https://dx.doi.org/10.1016/j.tplants.2014.03.004</a>","BEntID":316133,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":1,"RefStringPartII":". <i>Trends Plant Sci. 19(5)</i>: 292-303. <a href=\"https://dx.doi.org/10.1016/j.tplants.2014.03.004\" target=\"_blank\">https://dx.doi.org/10.1016/j.tplants.2014.03.004</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":0,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Gutiérrez, J.; Maere, S.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Gutiérrez, J.; Maere, S.","Englishabstract":"Systems biology-inspired genotype–phenotype mapping models are increasingly being used to study the evolutionary properties of molecular biological systems, in particular the general emergent properties of evolving systems, such as modularity, robustness, and evolvability. However, the level of abstraction at which many of these models operate might not be sufficient to capture all relevant intricacies of biological evolution in sufficient detail. Here, we argue that in particular gene and genome duplications, both evolutionary mechanisms of potentially major importance for the evolution of molecular systems and of special relevance to plant evolution, are not adequately accounted for in most GPM modeling frameworks, and that more fine-grained mechanistic models may significantly advance understanding of how gen(om)e duplication impacts molecular systems evolution.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Modeling the evolution of molecular systems from a mechanistic perspective","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-04-17 01:32:29.852785","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"evolutionary systems biology; genotype–phenotype mapping; emergent properties; gene duplication; genome duplication","OtherDescriptors":null,"Notes":null,"AnaPub":2014,"MonPub":null,"DateUpdate":"2020-04-02","DateCreate":"2020-04-02","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000336192900010","VABBcode":null,"OpenAcc":0,"DOI":"10.1016/j.tplants.2014.03.004"},"refs":null,"anarec":{"AnaID":322668,"PubliDate":2014,"Pagination":"292-303","XtraPublOfAnaID":null,"ISBN":null,"Volume":"19","Issue":"5","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":290672,"SerRR":"Trends in Plant Science. 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