{"refrec":{"BRefID":322722,"RR":"<b>Ghribi, F.; Richir, J.; Bejaoui, S.; Boussoufa, D.; Marengo, M.; El Cafsi, M.; Gobert, S.</b> (2020). Trace elements and oxidative stress in the Ark shell <i>Arca noae</i> from a Mediterranean coastal lagoon (Bizerte lagoon, Tunisia): are there health risks associated with their consumption? <i>Environm. Sc. & Poll. Res. 27</i>: 15607-15623. <a href=\"https://dx.doi.org/10.1007/s11356-020-07967-2\" target=\"_blank\">https://dx.doi.org/10.1007/s11356-020-07967-2</a>","BEntID":316193,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":1,"RefStringPartII":" <i>Environm. Sc. & Poll. Res. 27</i>: 15607-15623. <a href=\"https://dx.doi.org/10.1007/s11356-020-07967-2\" target=\"_blank\">https://dx.doi.org/10.1007/s11356-020-07967-2</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Ghribi, F.; Richir, J.; Bejaoui, S.; Boussoufa, D.; Marengo, M.; El Cafsi, M.; Gobert, S.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Ghribi, F. <i>et al.</i>","Englishabstract":"The current study examined the concentrations of ten trace elements (TE) (nickel, chromium, cadmium, iron, zinc, manganese, aluminum, copper, selenium and lead) in the edible tissue of the Ark shell <i>Arca noae</i> (L. 1758) from a Mediterranean coastal lagoon, the Bizerte lagoon during 2013–2014. The analysis of several redox status biomarkers, metallothioneins (MTs), malondialdehyde (MDA)<i>,</i> glutathione peroxidase (GPx), reduced glutathione (GSH) and acetylcholinesterase (AChE), was monitored as a response to TE bioaccumulation and environmental parameters variability. Significant differences (<i>p</i> < 0.05) were observed between mean seasonal TE concentrations in <i>A. noae</i> soft tissue. The highest TE concentrations in <i>A. noae</i> soft tissues were recorded during summer, which coincided with the increase of body dry weight (BDW) and the gonad index (GI). During this season, biomarker responses were enhanced, revealing significant increases of MTs, MDA and GSH levels as well as GPx activity in <i>A. noae</i> tissues, while a decrease of AChE activity was observed. The levels of TE analyzed in <i>A. noae</i> and several parameters used to assess the potential human risk (estimated weekly intake, target hazard quotient and target hazard risk) were lower than the permissible limits for safe seafood consumption. Consequently, this shellfish can be considered safe for human consumption. This preliminary study presents prospects for the valorization of this seafood product in Tunisia’s food sector. It also gives basal information for future environmental assessment studies in which <i>A. noae</i> could be used as early warning tools in the field of biomonitoring programs and confirms the usefulness of biomarkers to monitor the health status of aquatic organisms.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Trace elements and oxidative stress in the Ark shell <i>Arca noae</i> from a Mediterranean coastal lagoon (Bizerte lagoon, Tunisia): are there health risks associated with their consumption?","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-06-05 01:31:19.425156","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"Arca noae; Southern Mediterranean Sea; Trace elements; Contamination;Redox status; Human health","OtherDescriptors":null,"Notes":null,"AnaPub":2020,"MonPub":null,"DateUpdate":"2020-05-08","DateCreate":"2020-04-07","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000518073100001","VABBcode":null,"OpenAcc":0,"DOI":"10.1007/s11356-020-07967-2"},"refs":null,"anarec":{"AnaID":322722,"PubliDate":2020,"Pagination":"15607-15623","XtraPublOfAnaID":null,"ISBN":null,"Volume":"27","Issue":null,"BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":45312,"SerRR":"Environmental Science and Pollution Research. 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