{"refrec":{"BRefID":323003,"RR":"<b>Thuong, N.P.; Prondvai, E.; De Kegel, B.; De Wolf, T.; Witten, P.E.; Adriaens, D.</b> (2019). Morphological and histological characterization of an ectopically mineralized structure in a gilthead sea bream <i>Sparus aurata</i> with opercular deformation. <i>J. Fish Dis. 42(9)</i>: 1259-1270. <a href=\"https://dx.doi.org/10.1111/jfd.13044\" target=\"_blank\">https://dx.doi.org/10.1111/jfd.13044</a>","BEntID":316474,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":1,"RefStringPartII":". <i>J. Fish Dis. 42(9)</i>: 1259-1270. <a href=\"https://dx.doi.org/10.1111/jfd.13044\" target=\"_blank\">https://dx.doi.org/10.1111/jfd.13044</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Thuong, N.P.; Prondvai, E.; De Kegel, B.; De Wolf, T.; Witten, P.E.; Adriaens, D.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Thuong, N.P. <i>et al.</i>","Englishabstract":"In this study, we describe an abnormal ectopically mineralized structure (EMS) that was found inside the skull of a juvenile <i>Sparus aurata</i> that also showed a bilateral opercular deformation. The overall phenotype and tissue composition were studied using micro‐CT scanning and histological analyses. The ectopic structure occupies a large volume of the brain cavity, partially extruding into the gill cavity. It shows a dense mineralization and an extracellular matrix‐rich phenotype, with variation in both the morphology and size of the cell lacunae, combined with an irregular fibre organization inside the matrix. This study is the first to report such an EMS in a juvenile teleost fish, where the tissue does not resemble any other connective tissue type described in bony fish so far. The tissue phenotype seems to rule out that the EMS corresponds to a tumorous cartilage. Yet, it is rather reminiscent of a highly mineralized structure found in cartilaginous fish, where it is suggested to be associated with damage repair.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Morphological and histological characterization of an ectopically mineralized structure in a gilthead sea bream <i>Sparus aurata</i> with opercular deformation","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-04-22 01:32:09.964805","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"CT scanning; ectopically mineralized structure; histology; operculardeformities; Sparus aurata","OtherDescriptors":null,"Notes":null,"AnaPub":2019,"MonPub":null,"DateUpdate":"2020-04-20","DateCreate":"2020-04-07","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000479266500004","VABBcode":null,"OpenAcc":0,"DOI":"10.1111/jfd.13044"},"refs":null,"anarec":{"AnaID":323003,"PubliDate":2019,"Pagination":"1259-1270","XtraPublOfAnaID":null,"ISBN":null,"Volume":"42","Issue":"9","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":44476,"SerRR":"Journal of Fish Diseases. 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