{"refrec":{"BRefID":330970,"RR":"<b>Chelossi, E.; Pantile, R.; Pronzato, R.; Milanese, M.; Hentschel, U.</b> (2007). Bacteria with antimicrobial properties isolated from the Mediterranean sponges <i>Chondrilla nucula</i> and <i>Petrosia ficiformis</i>. <i>Aquat. Microb. Ecol. 49</i>: 157-163. <a href=\"https://dx.doi.org/10.3354/ame01134\" target=\"_blank\">https://dx.doi.org/10.3354/ame01134</a>","BEntID":324581,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":0,"RefStringPartII":". <i>Aquat. Microb. Ecol. 49</i>: 157-163. <a href=\"https://dx.doi.org/10.3354/ame01134\" target=\"_blank\">https://dx.doi.org/10.3354/ame01134</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Chelossi, E.; Pantile, R.; Pronzato, R.; Milanese, M.; Hentschel, U.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Chelossi, E. <i>et al.</i>","Englishabstract":"Bacteria were isolated seasonally from the Mediterranean sponges <i>Chondrilla nucula</i> and <i>Petrosia ficiformis</i> and screened for antibacterial activities. Selected isolates were taxonomically identified by 16S rRNA gene sequencing. A total of 416 different bacterial strains were isolated, 60 (14.4%) of which displayed variable degrees of antimicrobial activity. Of the bioactive strains, 58.3% were able to inhibit <i>Staphylococcus aureus</i>, 6.7% were active against <i>Bacillus subtilis</i>, 11.7% against both <i>Enterococcus faecalis</i> and <i>Escherichia coli</i>, 38.3% against <i>Pseudoalteromonas atlantica</i> and 33.3% against <i>Pseudomonas elongata</i>. 16S rRNA gene sequence analysis showed that 2 isolates, 1 from seawater samples and 1 from <i>P. ficiformis,</i> were most closely related to <i>Bacillus subtilis</i> (99% similarity) and that another isolate from <i>P. ficiformis</i> was most closely related to a previously described sponge-associated <i>Alphaproteobacterium</i> NW001 (98% similarity). Two isolates from <i>C. nucula</i> were most closely related to <i>Brachybacterium paraconglomeratum </i>(99% similarity) and <i>Shewanella algae</i> (89% similarity). The high percentage of bioactive isolates derived from the 2 sponges suggests that marine microorganisms, whether animal-associated or planktonic, are promising sources for drug discovery.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Bacteria with antimicrobial properties isolated from the Mediterranean sponges <i>Chondrilla nucula</i> and <i>Petrosia ficiformis</i>","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-04-22 01:32:14.027667","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"Antimicrobial activity · Associated bacteria · Chondrilla nucula · Petrosia ficiformis · Porifera · 16S rRNA","OtherDescriptors":null,"Notes":null,"AnaPub":2007,"MonPub":null,"DateUpdate":"2020-11-16","DateCreate":"2020-11-16","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000251749300005","VABBcode":null,"OpenAcc":1,"DOI":"10.3354/ame01134"},"refs":null,"anarec":{"AnaID":330970,"PubliDate":2007,"Pagination":"157-163","XtraPublOfAnaID":null,"ISBN":null,"Volume":"49","Issue":null,"BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":42201,"SerRR":"Aquatic Microbial Ecology. 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