{"refrec":{"BRefID":331055,"RR":"<b>Martijn, J.; Schön, M.E.; Lind, A.E.; Vosseberg, J.; Williams, T.A.; Spang, A.; Ettema, T.J.G.</b> (2020). Hikarchaeia demonstrate an intermediate stage in the methanogen-to-halophile transition. <i>Nature Comm. 11</i>: 5490. <a href=\"https://doi.org/10.1038/s41467-020-19200-2\" target=\"_blank\">https://doi.org/10.1038/s41467-020-19200-2</a>","BEntID":324666,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":1,"RefStringPartII":". <i>Nature Comm. 11</i>: 5490. <a href=\"https://doi.org/10.1038/s41467-020-19200-2\" target=\"_blank\">https://doi.org/10.1038/s41467-020-19200-2</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":0,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Martijn, J.; Schön, M.E.; Lind, A.E.; Vosseberg, J.; Williams, T.A.; Spang, A.; Ettema, T.J.G.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Martijn, J. <i>et al.</i>","Englishabstract":"Halobacteria (henceforth: Haloarchaea) are predominantly aerobic halophiles that are thought to have evolved from anaerobic methanogens. This remarkable transformation most likely involved an extensive influx of bacterial genes. Whether it entailed a single massive transfer event or a gradual stream of transfers remains a matter of debate. To address this, genomes that descend from methanogen-to-halophile intermediates are necessary. Here, we present five such near-complete genomes of Marine Group IV archaea (Hikarchaeia), the closest known relatives of Haloarchaea. Their inclusion in gene tree-aware ancestral reconstructions reveals an intermediate stage that had already lost a large number of genes, including nearly all of those involved in methanogenesis and the Wood-Ljungdahl pathway. In contrast, the last Haloarchaea common ancestor gained a large number of genes and expanded its aerobic respiration and salt/UV resistance gene repertoire. Our results suggest that complex and gradual patterns of gain and loss shaped the methanogen-to-halophile transition.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Hikarchaeia demonstrate an intermediate stage in the methanogen-to-halophile transition","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-04-18 01:32:20.099608","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":null,"Notes":null,"AnaPub":2020,"MonPub":null,"DateUpdate":"2020-11-17","DateCreate":"2020-11-17","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000588063600013","VABBcode":null,"OpenAcc":1,"DOI":"10.1038/s41467-020-19200-2"},"refs":null,"anarec":{"AnaID":331055,"PubliDate":2020,"Pagination":"5490","XtraPublOfAnaID":null,"ISBN":null,"Volume":"11","Issue":null,"BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":198717,"SerRR":"Nature Communications. 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