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Additional bioactive guanidine alkaloids from the Mediterranean sponge <i>Crambe crambe</i>. <i>Rsc Advances 2(7)</i>: 2828-2835. <a href=\"https://dx.doi.org/10.1039/c2ra00045h\" target=\"_blank\">https://dx.doi.org/10.1039/c2ra00045h</a>","BEntID":324759,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":1,"RefStringPartII":". <i>Rsc Advances 2(7)</i>: 2828-2835. <a href=\"https://dx.doi.org/10.1039/c2ra00045h\" target=\"_blank\">https://dx.doi.org/10.1039/c2ra00045h</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Bondu, S.; Genta-Jouve, G.; Leir?s, M.; Vale, C.; Guigonis, J.-M.; Botana, L.M.; Thomas, O.P.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Bondu, S. <i>et al.</i>","Englishabstract":"The full chemical reinvestigation of the Mediterranean marine sponge <span class=\"italic\">Crambe crambe</span> led to the isolation and structural characterization of 11 crambescin derivatives, including 8 new compounds, together with the known crambescidin 816. HRMS/MS studies allowed the complete assignment of the alkyl chain lengths of these guanidine alkaloids while the absolute configurations of all compounds were inferred from the comparison between experimental and theoretical circular dichroism spectra. 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