Document of bibliographic reference 331228

BibliographicReference record

Type
Bibliographic resource
Type of document
Journal article
BibLvlCode
AS
Title
Gracilosulfates A–G, monosulfated polyoxygenated steroids from the marine sponge Haliclona gracilis
Abstract
Seven new polyoxygenated steroids belonging to a new structural group of sponge steroids, gracilosulfates A–G (1–7), possessing 3β-O-sulfonato, 5β,6β epoxy (or 5(6)-dehydro), and 4β,23-dihydroxy substitution patterns as a common structural motif, were isolated from the marine sponge Haliclona gracilis. Their structures were determined by NMR and MS methods. The compounds 1, 2, 4, 6, and 7 inhibited the expression of prostate-specific antigen (PSA) in 22Rv1 tumor cells.
WebOfScience code
https://www.webofscience.com/wos/woscc/full-record/WOS:000581339500001
Bibliographic citation
Shubina, L.K.; Makarieva, T.N.; Denisenko, V.A.; Popov, R.S.; Dyshlovoy, S.A.; Grebnev, B.B.; Dmitrenok, P.S.; von Amsberg, G.; Stonik, V.A. (2020). Gracilosulfates A–G, monosulfated polyoxygenated steroids from the marine sponge Haliclona gracilis. Mar. Drugs 18(9): 454. https://dx.doi.org/10.3390/md18090454
Is peer reviewed
true
Access rights
open access
Is accessible for free
true

Authors

author
Name
Larisa Shubina
author
Name
Tatyana Makarieva
author
Name
Vladimir Denisenko
author
Name
Roman Popov
author
Name
Sergey Dyshlovoy
author
Name
Boris Grebnev
author
Name
Pavel Dmitrenok
author
Name
Gunhild von Amsberg
author
Name
Valentin Stonik

Links

referenced creativework
type
DOI
accessURL
https://dx.doi.org/10.3390/md18090454

taxonomic terms

taxonomic terms associated with this publication
Haliclona gracilis
Porifera [Sponges]

Document metadata

date created
2020-11-20
date modified
2020-11-20