{"refrec":{"BRefID":33220,"RR":"<b>Kahle, J.; Zauke, G.-P.</b> (2002). Bioaccumulation of trace metals in the copepod <i>Calanoides acutus</i> from the Weddell Sea (Antarctica): comparison of two-compartment and hyperbolic toxicokinetic models. <i>Aquat. Toxicol. 59(1-2)</i>: 115-135. <a href=\"https://dx.doi.org/10.1016/S0166-445X(01)00245-4\" target=\"_blank\">https://dx.doi.org/10.1016/S0166-445X(01)00245-4</a>","BEntID":33220,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":null,"RefStringPartII":". <i>Aquat. Toxicol. 59(1-2)</i>: 115-135. <a href=\"https://dx.doi.org/10.1016/S0166-445X(01)00245-4\" target=\"_blank\">https://dx.doi.org/10.1016/S0166-445X(01)00245-4</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":0,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Kahle, J.; Zauke, G.-P.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Kahle, J.; Zauke, G.-P.","Englishabstract":"Bioaccumulation of Cd, Co, Cu, Ni, Pb and Zn in the Antarctic calanoid copepod <i>Calanoides acutus</i> (Giesbrecht, 1902) was investigated during a cruise of <i>RV `Polarstern'</i> to the Weddell Sea. Main goals were to provide information on accumulation strategies of the organisms tested and to verify toxicokinetic models as a predictive tool. Except for Cd, the organisms accumulated metals upon exposure. It was possible to estimate significant model parameters of two-compartment and hyperbolic models. These models were successfully verified in a second toxicokinetic uptake study. The model verification was extended in a third uptake study with increasing external metal dosing. We found a linear increase of net uptake with external waterborne metal exposures up to 80 μg Pb l<sup>-1</sup>, with excellent predictions of the two-compartment model. For Co both models give reasonable predictions up to 20 μg Co l<sup>-1</sup>. Regarding Cu, Ni and Zn only hyperbolic model predictions were in good agreement with measured values up to 150 μg Cu l<sup>-1</sup>, 80 μg Ni l<sup>-1</sup> and 290 μg Zn l<sup>-1</sup>. Due to a decrease of Cd body burden in the experiments, only the hyperbolic model was applicable, leading to reliable predictions up to 20 μg Cd l<sup>-1</sup>. These concentrations largely determine the range for which these models may serve as a predictive tool.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Bioaccumulation of trace metals in the copepod <i>Calanoides acutus</i> from the Weddell Sea (Antarctica): comparison of two-compartment and hyperbolic toxicokinetic models","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-06-14 01:31:05.468436","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":"Antarctic; Biomonitoring; Metals; Toxicokinetic models; Zooplankton","Notes":null,"AnaPub":2002,"MonPub":null,"DateUpdate":"2003-03-17","DateCreate":"2003-03-17","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000176782000009","VABBcode":null,"OpenAcc":0,"DOI":"10.1016/S0166-445X(01)00245-4"},"refs":null,"anarec":{"AnaID":33220,"PubliDate":2002,"Pagination":"115-135","XtraPublOfAnaID":null,"ISBN":null,"Volume":"59","Issue":"1-2","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":42203,"SerRR":"Aquatic Toxicology. 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