{"refrec":{"BRefID":33357,"RR":"<b>Vargas-Albores, F.; Yepiz-Plascencia, G.</b> (2000). Beta glucan binding protein and its role in shrimp immune response. <i>Aquaculture 191</i>: 13-21","BEntID":33357,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":null,"RefStringPartII":". <i>Aquaculture 191</i>: 13-21","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Vargas-Albores, F.; Yepiz-Plascencia, G.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Vargas-Albores, F.; Yepiz-Plascencia, G.","Englishabstract":"Despite their relatively short life and assumed lesser complexity, crustaceans have mechanisms to detect foreign matter. In particular, they appear to recognize common characteristics present in bacteria and fungi, such as lipopolysaccharides (LPS) and ß-glucans. Although these microbial components can directly activate defensive cellular functions such as phagocytosis, melanization, encapsulation and coagulation, plasma recognition proteins amplify these stimuli. Beta glucan binding protein (BGBP) reacts with ß-glucans and the glucan-BGBP complex induces degranulation and the activation of prophenoloxidase (proPO). This protein is present in all crustaceans studied so far and is highly conserved. 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