{"refrec":{"BRefID":337131,"RR":"<b>Marques, A.; Custódio, M.; Guilherme, S.; Gaivão, I.; Santos, M.A.; Pacheco, M.</b> (2014). Assessment of chromosomal damage induced by a deltamethrin-based insecticide in fish (<i>Anguilla anguilla</i> L.) – A follow-up study upon exposure and post-exposure periods. <i>Pestic. Biochem. Physiol. 113</i>: 40-46. <a href=\"https://dx.doi.org/10.1016/j.pestbp.2014.06.003\" target=\"_blank\">https://dx.doi.org/10.1016/j.pestbp.2014.06.003</a>. <a href=\"https://hdl.handle.net/10.1016/j.pestbp.2014.06.003\" target=\"_blank\">https://hdl.handle.net/10.1016/j.pestbp.2014.06.003</a>","BEntID":333753,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":0,"RefStringPartII":". <i>Pestic. Biochem. Physiol. 113</i>: 40-46. <a href=\"https://dx.doi.org/10.1016/j.pestbp.2014.06.003\" target=\"_blank\">https://dx.doi.org/10.1016/j.pestbp.2014.06.003</a>. <a href=\"https://hdl.handle.net/10.1016/j.pestbp.2014.06.003\" target=\"_blank\">https://hdl.handle.net/10.1016/j.pestbp.2014.06.003</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":1,"BrackishFlag":1,"TerrestrialFlag":0,"Authorstring":"Marques, A.; Custódio, M.; Guilherme, S.; Gaivão, I.; Santos, M.A.; Pacheco, M.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Marques, A. <i>et al.</i>","Englishabstract":"The pyrethroid insecticide Decis®, containing deltamethrin as active ingredient, is among the most popular broad-spectrum biocides, with wide application in agriculture and home pest control. The occurrence of deltamethrin in the aquatic environment is well-established, but the possible genotoxic effects of Decis® in non-target organisms, namely fish, remain unknown. Hence, this work aimed to evaluate the cytogenetic damaging potential of Decis® in European eel (<i>Anguilla anguilla</i> L.), adopting the erythrocytic nuclear abnormalities (ENAs) assay. In addition, it was intended to investigate the damage progression in the post-exposure period. The frequency of immature erythrocytes (IE) was also determined to provide indirect information on the erythrocyte catabolism and erythropoiesis rate. Fish were exposed to 17.5 and 35 μg L<sup>−1</sup> of Decis® (equivalent to 0.05 and 0.1 μg L<sup>−1</sup> of deltamethrin, respectively) during 1 and 3 days. Thereafter, fish were transferred to clean water and kept for 1, 7 and 14 days. The results demonstrated a clear potential to induce chromosomal damage following 3 days exposure, depicted in an ENA frequency increase for both Decis® concentrations. The transient nature of this cytogenetic damage was also demonstrated, as ENA frequency returned to the control level 1 and 7 days after cessation of the exposure, respectively for the higher and the lower Decis® concentration. Moreover, this response pattern suggested a rapid metabolization and elimination of the formulation constituents by <i>A. anguilla</i>, combined with an increased erythrocyte turnover in fish exposed to the higher Decis® concentration, as pointed out by the IE frequency rise. Overall, the demonstrated genotoxic properties of Decis® pointed out increased risk factors to fish exposed to this insecticide.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Assessment of chromosomal damage induced by a deltamethrin-based insecticide in fish (<i>Anguilla anguilla</i> L.) – A follow-up study upon exposure and post-exposure periods","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-04-25 01:33:17.474387","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"Decis®; Genotoxicity; Chromosomal damage; Damage recovery; European eel","OtherDescriptors":null,"Notes":null,"AnaPub":2014,"MonPub":null,"DateUpdate":"2021-05-12","DateCreate":"2021-05-12","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000339860400006","VABBcode":null,"OpenAcc":0,"DOI":"10.1016/j.pestbp.2014.06.003","Handle":"10.1016/j.pestbp.2014.06.003"},"refs":null,"anarec":{"AnaID":337131,"PubliDate":2014,"Pagination":"40-46","XtraPublOfAnaID":null,"ISBN":null,"Volume":"113","Issue":null,"BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":43622,"SerRR":"Pesticide biochemistry and physiology. 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