{"refrec":{"BRefID":337916,"RR":"<b>Kumar, A.; Buia, M.C.; Palumbo, A.; Mohany, M.; Wadaan, M.A.M.; Hozzein, W.N.; Beemster, G.T.S.; AbdElgawad, H.</b> (2020). Ocean acidification affects biological activities of seaweeds: a case study of <i>Sargassum vulgare</i> from Ischia volcanic CO<sub>2</sub> vents. <i>Environ. Pollut. 259</i>: 113765. <a href=\"https://hdl.handle.net/10.1016/j.envpol.2019.113765\" target=\"_blank\">https://hdl.handle.net/10.1016/j.envpol.2019.113765</a>","BEntID":334540,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":1,"RefStringPartII":". <i>Environ. Pollut. 259</i>: 113765. <a href=\"https://hdl.handle.net/10.1016/j.envpol.2019.113765\" target=\"_blank\">https://hdl.handle.net/10.1016/j.envpol.2019.113765</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Kumar, A.; Buia, M.C.; Palumbo, A.; Mohany, M.; Wadaan, M.A.M.; Hozzein, W.N.; Beemster, G.T.S.; AbdElgawad, H.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Kumar, A. <i>et al.</i>","Englishabstract":"We utilized volcanic CO<sub>2</sub> vents at Castello Aragonese off Ischia Island as a natural laboratory to investigate the effect of lowered pH/elevated CO<sub>2</sub> on the bioactivities of extracts from fleshy brown algae <em>Sargassum vulgare</em> C. Agardh. We analysed the carbohydrate levels, antioxidant capacity, antibacterial, antifungal, antiprotozoal, anticancer properties and antimutagenic potential of the algae growing at the acidified site (pH ∼ 6.7) and those of algae growing at the nearby control site Lacco Ameno (pH∼8.1). The results of the present study show that the levels of polysaccharides fucoidan and alginate were higher in the algal population at acidified site. In general, extracts for the algal population from the acidified site showed a higher antioxidant capacity, antilipidperoxidation, antibacterial, antifungal, antiprotozoal, anticancer activities and antimutagenic potential compared to the control population. The increased bioactivity in acidified population could be due to elevated levels of bioactive compounds of algae and/or associated microbial communities. In this snapshot study, we performed bioactivity assays but did not characterize the chemistry and source of presumptive bioactive compounds. 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